Dendritic cell control of immune responses / / topic editors, Penelope Anne Morel, University of Pittsburgh, USA, Lisa Helene Butterfield, University of Pittsburgh, USA.
Dendritic cells (DC) are among the first cells to encounter pathogens and damage in peripheral tissues and, upon activation, DC migrate to lymph nodes where they activate and educate T cells to initiate and shape the immune response. DC present pathogen-derived antigen to T cells and drive T cell di...
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Superior document: | Frontiers Research Topics |
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Year of Publication: | 2016 |
Language: | English |
Series: | Frontiers Research Topics
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Physical Description: | 1 electronic resource (121 p.) |
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Dendritic cell control of immune responses / topic editors, Penelope Anne Morel, University of Pittsburgh, USA, Lisa Helene Butterfield, University of Pittsburgh, USA. Frontiers Media SA 2016 1 electronic resource (121 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics Dendritic cells (DC) are among the first cells to encounter pathogens and damage in peripheral tissues and, upon activation, DC migrate to lymph nodes where they activate and educate T cells to initiate and shape the immune response. DC present pathogen-derived antigen to T cells and drive T cell differentiation into particular effector cells through the expression and secretion of co-stimulatory molecules and cytokines respectively. The study of DC biology has included the identification of multiple DC subsets in tissues and lymphoid organs, the differentiation and plasticity of DC subsets, the functional consequences of DC interaction with pathogen, control of DC migratory properties and the impact of DC on T cell activation and differentiation. In recent years sophisticated systems biology approaches have been developed to deepen our understanding of DC function. These studies have identified differences between DC subsets located in various tissues and critical factors that drive the outcome of the interaction between DC and T cells. DC are currently being used in in various clinical therapeutic settings, including as vaccines for cancer and autoimmune disease. A clear understanding of DC factors that contribute to specific immune responses is vital to the success of DC based therapies. This research topic will give a comprehensive overview of current issues in DC biology and provides an update on the clinical uses of DC in the therapy of autoimmunity and cancer. English Creative Commons NonCommercial-NoDerivs https://creativecommons.org/licenses/http://journal.frontiersin.org/researchtopic/1458/dendritic-cell-control-of-immune-responses Description based on online resource ; title from PDF title page (viewed on 03/14/2021) Unrestricted online access star Autoimmunity Dendritic Cells Immune Regulation T cells Cancer Dendritic cells Immunology. 2-88919-868-5 Butterfield, Lisa Helene, editor. Morel, Penelope Anne, editor. |
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English |
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eBook |
author2 |
Butterfield, Lisa Helene, Morel, Penelope Anne, |
author_facet |
Butterfield, Lisa Helene, Morel, Penelope Anne, |
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l h b lh lhb p a m pa pam |
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TeilnehmendeR TeilnehmendeR |
title |
Dendritic cell control of immune responses / |
spellingShingle |
Dendritic cell control of immune responses / Frontiers Research Topics |
title_full |
Dendritic cell control of immune responses / topic editors, Penelope Anne Morel, University of Pittsburgh, USA, Lisa Helene Butterfield, University of Pittsburgh, USA. |
title_fullStr |
Dendritic cell control of immune responses / topic editors, Penelope Anne Morel, University of Pittsburgh, USA, Lisa Helene Butterfield, University of Pittsburgh, USA. |
title_full_unstemmed |
Dendritic cell control of immune responses / topic editors, Penelope Anne Morel, University of Pittsburgh, USA, Lisa Helene Butterfield, University of Pittsburgh, USA. |
title_auth |
Dendritic cell control of immune responses / |
title_new |
Dendritic cell control of immune responses / |
title_sort |
dendritic cell control of immune responses / |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
publisher |
Frontiers Media SA |
publishDate |
2016 |
physical |
1 electronic resource (121 p.) |
isbn |
2-88919-868-5 |
callnumber-first |
Q - Science |
callnumber-subject |
QR - Microbiology |
callnumber-label |
QR185 |
callnumber-sort |
QR 3185.8 D45 |
illustrated |
Not Illustrated |
dewey-hundreds |
600 - Technology |
dewey-tens |
610 - Medicine & health |
dewey-ones |
616 - Diseases |
dewey-full |
616.07/9 |
dewey-sort |
3616.07 19 |
dewey-raw |
616.07/9 |
dewey-search |
616.07/9 |
work_keys_str_mv |
AT butterfieldlisahelene dendriticcellcontrolofimmuneresponses AT morelpenelopeanne dendriticcellcontrolofimmuneresponses |
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(CKB)3710000001092124 (oapen)https://directory.doabooks.org/handle/20.500.12854/44725 (EXLCZ)993710000001092124 |
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hierarchy_parent_title |
Frontiers Research Topics |
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Dendritic cell control of immune responses / |
container_title |
Frontiers Research Topics |
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