Signal Transduction and Smooth Muscle

• Superior document: Methods in Signal Transduction Ser.
• Author: Trebak, Mohamed.
• TeilnehmendeR: Earley, Scott.
• Year of Publication: 2018
• Language: English
• Series: Methods in Signal Transduction Ser.
• Physical Description: 1 online resource (chapter 9, pages 173-190) :; charts; digital file(s).
• Notes: Description based upon print version of record.

All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling.

Table of Contents

Cover; Half Title; Title Page; Copyright Page; Table of Contents; Series Preface; Preface; Editors; Contributors; Chapter 1: Elucidation of Vasopressin Signal Transduction Pathways in Vascular Smooth Muscle; Chapter 2: Investigating Chloride Channels in Smooth Muscle; Chapter 3: Methods for the Isolation of and Study of Ca2+ Signaling in Arteriolar Smooth Muscle Cells; Chapter 4: Ion Channel Trafficking in Arterial Smooth Muscle Cells and Functional Significance; Chapter 5: Total Internal Reflection Fluorescence Microscopy in Vascular Smooth Muscle

Chapter 6: T-Type Ca2+ Channels in Vascular Smooth Muscle: Properties, Regulation, and FunctionChapter 7: Calcium Sensitization in Smooth Muscle Involving Regulation of Myosin Light Chain Phosphatase Activity; Chapter 8: Approaches for Investigating the Functional Significance of Transient Receptor Potential Cation Channels in Smooth Muscle Cells; Chapter 9: Mitochondria Structure and Position in the Local Control of Calcium Signals in Smooth Muscle Cells; Chapter 10: ORAI Channels in Vascular Smooth Muscle

Chapter 11: G Protein-Coupled Receptors in Airway Smooth Muscle Function and Obstructive Lung DiseaseChapter 12: Brain-Derived Neurotrophic Factor in Airway Smooth Muscle: Contributions to Asthma; Chapter 13: Antibody-Based Approaches for Protein Analysis of Smooth Muscles; Chapter 14: Role of Ion Channels in Urinary Bladder Smooth Muscle Function; Chapter 15: Methods for Investigating the Regulation of Smooth Muscle Excitability by Interstitial Cells; Chapter 16: Electrical Pacemaking in Lymphatic Vessels; Chapter 17: NADPH Oxidase, Redox Signaling, and Vascular Smooth Muscle Function; Index