Herpesviridae / / edited by Joseph Ongrádi.
Herpesviruses are unique among viruses as they encode for a complex self-regulatory system, aggressively invade and persist in the host, evade immune defense, alter all regulatory mechanisms of the macroorganism and modify the replication of heterologous viruses. Environmental factors influence thes...
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| Place / Publishing House: | Rijeka, Croatia : : IntechOpen,, [2016] ©2016 |
| Year of Publication: | 2016 |
| Language: | English |
| Physical Description: | 1 online resource (272 pages) :; illustrations |
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| Summary: | Herpesviruses are unique among viruses as they encode for a complex self-regulatory system, aggressively invade and persist in the host, evade immune defense, alter all regulatory mechanisms of the macroorganism and modify the replication of heterologous viruses. Environmental factors influence these unconventional relationships. Consequently, a single herpesvirus species can be attributed to a wide range of diseases as etiological agents or cofactors. This book is intended to give an overview on selected clinical hot topics: herpes simplex virus encephalitis, persistent infection in the gingiva, thymidine kinase gene expression causing male infertility, and pharmaceutical reactivation of Epstein-Barr virus for oncolysis. Immune evasion mechanisms and new ways to formulate vaccines are exhaustively reviewed. Finally, a surprise: bovine herpesviruses could serve as models to study the pathomechanism of herpesviruses. |
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| Bibliography: | Includes bibliographical references. |
| ISBN: | 9535141856 9535126113 |
| Hierarchical level: | Monograph |
| Statement of Responsibility: | edited by Joseph Ongrádi. |