Progress in Tryptophan and Serotonin Research : : Proceedings. Fourth Meeting of the International Study Group for Tryptophan Research ISTRY, Martinsried, Federal Republic of Germany, April 19-22, 1983 / / ed. by H. G. Schlossberger, H. Steinhart, International Study Group for Tryptophan Research, W. Kochen, B. Linzen.

• Superior document: Title is part of eBook package: De Gruyter DGBA Medicine and Life Sciences - <1990
• MitwirkendeR: Adell, Albert,; Affiah, I. U.,; Affolter, Hubert,; Agarwal, D. P.,; Allegri, G.,; Allegri, Graziella,; Anderson, George M.,; Angi, Mario R.,; Angst, J.,; Annable, L.,; Aratô, Mihâly,; Arendt, Josephine,; Arimanana, L.,; Arslan, M.,; Artigas, Francesc,; Ashley, D. V.,; Ashley, D.,; Badawy, A. A. -B.,; Badawy, Abdulla A. -B.,; Balogh-Hergovich, É.,; Banki, Csaba M.,; Bardou, Louis-Georges,; Baumann, P.,; Baumert, Alfred,; Baumgarten, Hans Georg,; Beaton, David W.,; Bender, D. A.,; Bender, David A.,; Besson, Jean-Marie,; Bettero, Antonio,; Biekert, E.,; Bigot, Jean-Claude,; Bineau-Thurotte, Magali,; Birnbaum, D.,; Bodammer, G.,; Bode, R.,; Bos, Klaas D.,; Bousquet, Bernard,; Bouthier, A. E.,; Breeze, R. G.,; Brown, Gregory M.,; Brüning, G.,; Burns, Timothy G.,; Butler, Stephen H.,; Byrd, D. J.,; Bückmann, D.,; Caleri, Daniela,; Cardin dè Stefani, E.,; Carlson, J. R.,; Ceccherelli, Francesco,; Cesura, Andrea M.,; Chouinard, G.,; Collard, Keith J.,; Cook, J. S.,; Cooke, Helen J.,; Corkin, Suzanne,; Costa, C.,; Costa, Carlo,; Crokaert, R.,; Curtius, H. -Ch.,; Curzon, G.,; Dacey, Anthony,; Dalzoppo, D.,; Danielczyk, W.,; De Antoni, A.,; De Bruin, E. P.,; De Clerck, Fred,; De Luca, G.,; Del Re, Paola,; Dewart, Dorothy,; Di Stazio, G.,; Dreux, Claude,; Duine, J. A.,; Einhäupl, Karl,; Erne, Paul,; Ervin, F. R.,; Escande, Christine,; Esumi, M.,; Evans, Myrddin,; Fanciullacci, Marcello,; Ferenci, P.,; Fernstrom, John D.,; Finot, P. -A.,; Finot, P. A.,; Fleury, M.,; Fontana, A.,; Frank, J.,; Friedman, Mendel,; Fujiki, H.,; Fujimoto, H.,; Furniss, D.,; Garnier, Jean-Pierre,; Geeraerts, F.,; Gelpí, Emili,; Ghosh, D.,; Gieren, A.,; Glowinski, J.,; Goda, Kiyoshi,; Godefroy, Françoise,; Goedde, H. W.,; Gommeren, Walter,; Graaff, W. van der,; Grahn, H.,; Grandi, C.,; Greef, Jan van der,; Greenwald, Daniel,; Grimm, Ulrich,; Grota, Lee J.,; Große, Wolfgang,; Gruber, Friedrich,; Grätz, R.,; Gröger, Detlef,; Guilford, J.,; Hamasaki, T.,; Hankes, L. V.,; Hardwick, S.,; Hartmann, E.,; Hartmann, Ernest,; Hattori, Masayasu,; Hayaishi, O.,; Hayaishi, Osamu,; Hecker, E.,; Henderson, L. L.,; Hiruma, K.,; Huether, G.,; Huether, Gerald,; Hunneman, D.,; Hurrell, R. F.,; Hurrell, Richard F.,; Ikeda, Sayoko,; Inada, J.,; Inoue, S.,; Inoue, Shintaro,; Ishiguro, I.,; Jackson, Eric,; Jaenicke, Lothar,; Jansen, C. R.,; Jellinger, K.,; Jenner, P.,; Jirgensons, Jánis,; Johnson, J. A.,; Jongejan, J. A.,; Joseph, M. H.,; Joseph, Michael H.,; Jzn,,; Kadota, K.,; Kalyanasundaram, S.,; Kennett, G. A.,; Kennett, Guy A.,; Kido, R.,; Kienzl, E.,; Kimura, M.,; Kissinger, P. T.,; Klemm, Hans Peter,; Knapp, Alwin,; Koeb, L.,; Korićanac, Zagorka,; Kotake, Yahito,; Kotake, Yazo,; Kröger, H.,; Kumagai, R.,; Kurcz, Mihâly,; Lamm, V.,; Langenbach-Schmidt, D.,; Leathwood, P. D.,; Leathwood, P.,; Leathwood, Peter,; Leupold, D.,; Levin, Carol E.,; Levine, R. A.,; Leysen, Josée E.,; Leysen, Josée,; Liardon, R.,; Lieberman, Harris R.,; Lingens, Franz,; Lise, M.,; Lovenberg, W.,; Magboul, B. I.,; Magnenat, E.,; Majumdar, A. P. N.,; Mancusi, Ludovico,; Marin, Gino,; Marston, A.,; Martínez, Emili,; Materazzi, M.,; Menez, Jean-François,; Menke, Karl-Heinz,; Meuter, H.,; Milech, U.,; Milovanović, Dragoslav,; Milovanović, Ljiljana,; Miyake, Akio,; Moennoz, D.,; Moineau, Marie-Pierre,; Montague, William C.,; Morand, C.,; Mori, Terutoshi,; Moroder, L.,; Munoz-Clares, R. A.,; Müldner, H.,; Müller, Kurt,; Müller, R.,; Nagao, M.,; Nagarnura, Y.,; Naito, J.,; Nedopil, Norbert,; Neuhoff, V.,; Nicholas, A.,; Niederwieser, A.,; Nielsen, H. K.,; Nielsen, Henrik K.,; Nitti, D.,; Nocerini, M. R.,; Noma, Amy T.,; Nomura, S.,; Ogawa, H.,; Ohta, V.,; Okuno, E.,; Osborne, Neville N.,; Otsuka, H.,; Otsuka, Hidetsugu,; Palamara, G.,; Papp, Zsuzsa,; Patel, Saraswati,; Philippu, G.,; Pletscher, Alfred,; Pogson, Ch. I.,; Pogson, Ch.,; Politi, V.,; Pollack, Robert L.,; Pollet, Patricia,; Pratt, J.,; Price, Christopher J.,; Psarakis, Stella,; Pée, K.-H. van,; Raba, M.,; Ramanamurthy, P. S. V.,; Reiter, Russel J.,; Rembold, H.,; Reynolds, E. H.,; Riddiford, L. M.,; Riederer, P.,; Rivier, L.,; Rommelspacher, H.,; Roth, E.,; Rudzite, Vera,; Rüther, Eckart,; Salmon, Silvia,; Sarna, G. S.,; Sasai, Y.,; Sasaki, A.,; Sasaki, Atuko,; Schaik, Frank van,; Schimpfessel, L.,; Schlossberger, Hans Georg,; Schmaeler, M.,; Schott, H.-H.,; Schott, K.,; Schrappe, O.,; Schreurs, Wil H. P.,; Schrijver, Jaap,; Seemann, D.,; Seltzer, Samuel,; Shibata, Y.,; Shibata, Yukio,; Shinohara, R.,; Shorvon, S. D.,; Sicuteri, Federigo,; Sileniece, Gunta,; Smith, S. A.,; Soubrié, P.,; Speier, G.,; Stanković, Branka,; Stanley, J.,; Steinberg, Reinhard,; Steinhart, Hans,; Sturm, M.,; Stöckigt, J.,; Stützle, Petra,; Suganuma, M.,; Sugimura, T.,; Sullivan, D. T.,; Suter, Hugh A.,; Suzuki, T.,; Suzuki, Takeshi,; Suñol, Cristina,; Tahira, T.,; Takahashi, Hitoshi,; Takai, K.,; Takai, Katsuji,; Takayama, S.,; Takeuchi, F.,; Takikawa, O.,; Takikawa, Osamu,; Talsky, Gerhard,; Thompson, I.,; Tichy, Sibylle,; Toulmé, Jean-Jacques,; Tran, Gilles,; Trpković, Dragan,; Tusell, Josep M.,; Ueda, Takashi,; Uemura, T.,; Ugata, M.,; Umebachi, Y.,; Umebachi, Yoshishige,; Votisky, Erika,; Wakabayashi, K.,; Weil-Fugazza, Jeanne,; Wieland, Th.,; Wilkinson, Lawrence S.,; Witkop, Bernhard,; Woggon, B.,; Wolf, H.,; Wurtman, Richard J.,; Wünsch, E.,; Xhonneux, Benoit,; Yagi, S.,; Yasuhira, K.,; Yasui, H.,; Yasui, Hiroaki,; Yatnada, M.,; Yokomine, R.,; Yoshida, R.,; Yoshida, Ryotaro,; Young, S. N.,; Young, Simon N.,; Yuyama, S.,; Yuyama, Shunsuke,; Zahnley, James C.,; Zambonin, M.,; Zavala, F.,; Ziemsen, B.,; Zigman, S.,; Zinke, K.,; Zogno, A.,
• HerausgeberIn: International Study Group for Tryptophan Research, ,; Kochen, W.,; Linzen, B.,; Schlossberger, H. G.,; Steinhart, H.,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2019]; ©1984
• Year of Publication: 2019
• Edition: Reprint 2019
• Language: English
• Physical Description: 1 online resource (889 p.) :; Num. figs.

Table of Contents

• Frontmatter
• Preface
• CONTENTS
• OPENING SESSION
• Adolf Butenandt's Work on the Metabolism of Tryptophan
• Tryptophan, the Heart of the Toxic Peptides from Amanita Mushrooms
• Forty Years of Trypto-Fun
• Indoleamine Dioxygenase - a Possible Biological Function
• QUALITATIVE AND QUANTITATIVE ANALYSIS OF TRYPTOPHAN AND ITS METABOLITES
• Liquid Chromatography/Electrochemistry Determination of Biogenic Amines: Improved Performance Using Low Dead Volume Multiple Electrode Transducers
• GLC and HPLC Analysis of Tryptophan, Kynurenine and Related Metabolites
• Monitoring of Tryptophan Levels in Biological Fluids by HPLC: An Improved Method
• Rapid Determination of Tryptophan and its Metabolitesalong the Kynurenine Pathway by HPLC
• HPLC-Analysis of Xanthurenic Acid and its 8-Methyl-Ether
• Free and Total Tryptophan Microdetermination by an Automated Fluorometric Method
• Comparison of HPLC and GC-MS Methods for the Determination of Tryptophan and its Indole Metabolites in Biological Samples
• Pineal Indoles: Their Determination by High Performance Liquid Chromatography and the Influence of Diurnal Variation and Tryptophan Administration on their Level in the Rat
• Higher-Order Derivative Spectrophotometry for the Quantitative Determination of Tryptophan, Tyrosine and Phenylalanine in Two- and Three-Component Mixtures, Peptides and Proteins
• The Application of a Spectrofluorometer-Optical- Multichannel Analyzer System to the Determination of Tryptophan
• Picomole Determination of Tryptophan by Derivatization to 9-Hydroxymethyl-ß-Carboline
• Determination of Tryptophan in Food after Alkaline Hydrolysis: An Evaluation
• Colorimetric Determination of Tryptophan in Corn-Cob Mix (CCM)
• Comparison of Tryptophan Assays for Food Proteins
• WORKSHOP: ANALYSIS OF TRYPTOPHAN
• Discussion at the Workshop on "Analysis of Tryptophan"
• TRYPTOPHAN AND SEROTONIN: NEUROBIOLOGY
• Tryptophan Transport to the Brain: Newer Findings and Older Ones Reconsidered
• Tryptophan Availability and Serotonin Synthesis in Rat Brain: Effects of Experimental Diabetes
• Anatomy and Function of Central Serotoninergic Neurons
• Serotonin Receptor Binding Sites: Localization and Role in the Brain and Peripheral Tissues
• Involvement of 5-HT2 (S2)- Receptor Sites in the Serotonin-Induced Activation of Cat Platelets
• The Regulation of 5-Hydroxytryptamine Release from Superfused Synaptosomes by Tryptophan
• Selective Increases in High Affinity Tryptophan Transport in Synaptosomes from Different Brain Areas Incubated in Sodium-Free Media
• Formation and Function of Tetrahydro-ß-Carbolines with Special Reference to their Action on [3H] - Tryptamine Binding Sites
• Regulations of Serotonergic Neurons Innervating the Basal Ganglia: In vivo Release Studies
• Blood Platelets as Models for Neurons: Similarities of the 5-Hydroxytryptamine Systems
• In vivo Metabolism of 14C-5-HT, 14C-5.6-DHT and 14C-5.7-DHT by MAO/COMT/Aldehyde Dehydrogenase in Rat Brain
• Tryptophan Metabolism in the Pineal Gland
• Some Physiological Responses and Effects of the Pineal Indoleamine Melatonin
• Pharmacologic Regulation of Serum N-Acetylserotonin
• N-Acetyltryptophan: Biochemical and Pharmacological Studies
• Serotonin, a Major Metabolite of Tryptophan in the Rabbit Retina
• Effect of 5-Hydroxyanthranilic Acid on Arachidonate Metabolites Function in Platelet Aggregation System
• WORKSHOP: CLINICAL AND BEHAVIOURAL EFFECTS OF TRYPTOPHAN
• Introduction to Workshop
• Tryptophan and Human Sleep: An Analysis of 43 Studies
• L-Tryptophan in Chronic Insomnia
• Tryptophan (500 mg) Decreases Subjectively Perceived Sleep Latency and Increases Sleep Depth in Man
• Further Evidence of the Hypnotic Properties of Tryptophan
• The Therapeutic Action of Tryptophan in Depression, Mania, and Aggression
• The Effects of Dietary Tryptophan on Chronic Maxillofacial Pain Tolerance
• PATHOLOGY, CLINICAL ASPECTS
• Modulation of Serotonin Receptors by L-Valine in Hepatic Encephalopathy
• Effect of a B-Vitamin on Tryptophan Metabolism in South African Bantu with Pellagra
• Studies on the Urinary Excretion of Xanthurenic Acid in Diabetics
• Urinary Excretion of Xanthurenic Acid and Zinc in Diabetes
• Studies of the Clinical Importance and Molecular Defect of Hereditary Vitamin B6 Dependent Xanthurenic Aciduria
• Tryptophan - Nicotinic Acid Pathway in Cardiovascular Diseases
• The Dependence of Stress Induced Increases in Functional 5HT Activity on Increased Tryptophan Availability: Evidence that in vivo Electrochemistry Monitors 5-Hydroxyindole Release
• Increased Availability of Tryptophan to the Brain in Stress is not Mediated via Changes in Competing Amino Acids
• Free and Bound Plasma Tryptophan Levels in Psychiatric Disorders
• Cerebrospinal Fluid 5HIAA and Tryptophan in Depression and Suicide
• The Influence of L5-Hydroxytryptophan (L5-HTP) on Clinical and Biochemical Parameters in Depressive Patients
• Plasma Tryptophan Levels and 5-Hydroxytryptamine Synthesis in the Brain and the Spinal Cord in "Arthritic" Rats
• Effects of Antirheumatic Drugs and Tricyclic Antidepressants on Total and Free Serum Tryptophan Levels in Arthritic Rats
• Tryptophan, Serotonin and 5-Hydroxyindoleacetic Acid Levels in Human CSF in Relation to Pain
• Dynamics of Plasma Tryptophan Following Antimigraine Drugs
• Comparison of Morphine and Meptazinol Effects on Rat Tryptophan Disposition and Metabolism
• Decreased Concentrations of Tryptophan and Serotonin in the Brain of Developing Hyperphenylalaninemic Rats - A Contribution to the Understanding of the Metabolic Effects in Phenylketonuria
• Cofactor Dependency of Serotonin and Catecholamine Biosynthesis in Patients with Atypical Phenylketonuria and Endogenous Depression
• Tryptophan, 5-Hydroxytryptophan and Dopa Metabolism in the Rat with Experimental Phenylketonuria
• The Role of Tryptophan Oxidation in Ocular Tissue Damage
• Tryptophan and Kynurenine in Senile Cataract
• Urinary 5-Hydroxyindoleacetic Acid and Serum Phénobarbital of Children Suffering from Epilepsy
• Anticonvulsant Drugs Produce Different Effects on Plasma Tryptophan Concentrations in Epileptic Patients
• The Role of Metabolism in 3-Methylindole-Induced Acute Lung Injury
• Beta-Carboline Levels in Blood of Smokers and Non-Smokers
• The Relationship between Tryptophan, Tryptophan Metabolites and Bladder Cancer
• Role of Indoleamine 2,3-Dioxygenase in the Defence Mechanism against Tumor Growth
• The Relationship between Plasma Kynurenine and Indoleamine 2,3-Dioxygenase Activity in the Extrahepatic Tissues
• L-Tryptophan Metabolism along the Kynurenine Pathway in Human Malignant Melanoma
• NUTRITIONAL ASPECTS
• Content and Stability of Tryptophan in Foods
• Increased Aromatic Amine (Kynurenine) in Dried Fish Meat under Sunlight
• Tryptophan Requirement of Farm Animals
• Pattern of Radioactivity from Endogenous 3H-Tryptophan Excreted in the Urine of Fasted or Rats Fed Diets Containing Different Levels of Casein
• Protein/Carbohydrate Selection in Rats Following Administration of Tryptophan, Glucose or a Mixture of Amino Acids
• Influence of Tryptophan on Gastric Mucosal Protein Synthesis
• Tryptophan and Intestinal Secretion
• Tryptophan Metabolism in Undernourished Developing Rat Brain
• Effect of Tryptophan on Protein Utilization and Energy Intake of Pigs
• A High Carbohydrate, Protein-Free Meal, either at Breakfast or in the Evening Does not Alter Plasma Tryptophan to Large Neutral Amino Acid Ratios in Healthy Men
• Effects of Large Neutral Amino Acids on Tryptophan Transport into the Brain during Development
• Contribution of Exegenous N15 -Tryptophan to Plasma and Red Blood Cell Tryptophan and Kynurenine in Healthy Humans
• Carbohydrate Meal Increases Brain 5-Hydroxytryptamine Synthesis in the Adult Rat only after Prolonged Fasting
• Exogenous Tryptophan: A Study of its Effects on the Levels of Aromatic Amine(s) in Cerebral and Hepatic Tissues in Mice
• Influence of Excess Leucine Intake on the Conversion of Tryptophan to NAD in Rats Fed Low Protein Diet
• The Pellagragenic Action of a Dietary Excess of Leucine: Effects of a High-Leucine Diet on Tryptophan Metabolism
• Effect of Cadmium on some Key Enzymes of Tryptophan - NAD
• Pathway in Rats in vivo
• The Influence of Increased Availability of Tryptophan on the Formation of Tryptamine and Serotonin during Early Ontogenesis
• TRYPTOPHAN METABOLISM IN MAMMALS
• Tryptophan Metabolism and its Control in Mammalian Liver
• Tryptophan Metabolism by the Isolated, Perfused Liver and Kidney of Rat (Quantification of the Metabolism by the Compartmental Analysis)
• Effects of Oestrogens on the Metabolism of Tryptophan Implications for the Interpretation of the Tryptophan Load Test for Vitamin B6 Nutritional Status
• The Functions and Regulation of Tryptophan Pyrrolase
• Kynurenine Aminotransferase Activity in Human and other Mammalian Tissues
• Intracellular Localization and Characterization of 3-Hydroxykynureninase in Human Liver
• Time-Course of 5-HTP Metabolism in Rabbits: Relevance of Transaminating Pathway
• Tryptophan Aminotransferase Activity in Rat Liver
• The Oxygenation of Tryptophan and Indoles with Superoxide Ion and Dioxygen in the Presence of Copper and Ruthenium Catalysts
• Serotonin- and Melatonin-Dependent Light Emission Induced by Xanthine Oxidase
• The in vivo Effect of Sodium Fluoride on the Key Enzymes of Tryptophan Metabolism
• Roles of Active Oxygen and Superoxide Dismutase in Anthranilatnide Hydroxylation and its Derived Phenoxazinone-Like Pigment Formation by Rat Liver Microsomal Monooxygenase System
• Protective Effect of Tryptophan upon the Influence of N-Methylformamide on the Development, the NAD Synthesis, and the Activity of the Adenosine Diphosphate Ribosyl Transferase of Rat Embryos
• Induction of Tyrosine Aminotransferase by Tryptophan in Rat Liver
• TRYPTOPHAN METABOLISM IN INSECTS
• Tryptophan Metabolism in Drosophila
• Roles of Active Oxygen and Catalase in the Formation of Phenoxazinone Pigments Catalysed by Manganese Ion
• Ommochrome-Potassium Urate Complex as Pigment of Red Faeces of Locusta migratoria (Insecta, Orthoptera, Acrididae)
• Changes in Fluorescence and Size of the Cytoplasmic Granules in the Malpighian Tubules of Drosophila melanogaster Linked with Tryptophan Metabolism
• Hormonal Control of Pigmentation in Manduca sexta
• Tryptophan Metabolism and Morphological Color Change in Insects
• The Structure of Papiliochrome II, the Yellow Wing Pigment of the Papilionid Butterflies
• Some Chemical Properties of Papiliochrome R
• TRYPTOPHAN METABOLISM IN PLANTS AND MICROORGANISMS
• Metabolism of Tryptophan in Pseudomonas aureofaciens
• Does Tryptophan Side Chain Oxidase from Pseudomonas ATCC 29574 Contain a Quinoprotein?
• Tryptophan Side Chain Oxidase (TSO) - Structure and Reaction Mechanism
• Characterization of three Tryptophan Aminotransferases from Candida maltosa
• Anthranilate Hydroxylase and the Short-Cut-Pathway for the Biosynthesis of Nicotinamide Nucleotides in Aspergillus niger
• Biosynthesis of Tryptophan Derived Alkaloids in Higher Plants: Enzymati Formation of the Sarpagine-Ajmaline Group
• Acridone Alkaloid Biosynthesis in Tissue Cultures of Ruta graveolens
• Isolation and Biological Activities of Diterpene Anthraniloyl and 3-Hydroxyanthraniloyl Peptide Esters from Euphorbia mi Iii
• New Biological Significance of Indole-Containing Compounds as Initiators or Tumor Promoters in Chemical Carcinogenesis
• Biosynthesis of Serotonin and Auxin in Seeds of Juglans regia
• Blepharismone: a Conjugation-Inducing Tryptophan Derivative in the Ciliate Blepharisma
• Biological Activity of Blepharismone Derivatives - An Approach Towards Biogenesis of the Hormone
• TRYPTOPHAN IN PROTEINS AND PEPTIDES
• Advances in the Chemical Modification of Tryptophan in Peptides and Proteins
• Peptide Bond Cleavage at Tryptophan with Cyanogen Bromide - Mechanism of the Reaction
• Tryptophan, a Pitfall for the Peptide Chemist
• Photochemical arid Radiochemical Reactions of Tryptophan: Modification of a Single-Strand Binding Protein from Bacteriophage T4
• X-Ray Structure Analyses of Tryptophan Derivatives as Models for Stereochemical Aspects of the Toxic Peptides from Amanita Mushrooms
• AUTHOR INDEX
• SUBJECT INDEX
• ABBREVATIONS
• Backmatter