Heparin. New biochemical and medical aspects : : Proceedings of the symposium of the Deutsche Gesellschaft für Klinische Chemie, Titisee, Breisgau, Germany June 29th–July 1st, 1981 / / ed. by Irene Witt.
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Table of Contents:
- Frontmatter
- Preface
- Introductory Welcome
- List Of Participants
- Contents
- I. Heparin: Structure, Mechanism of Action, Biosynthesis and Catabolism
- The Function and Structure of the Heparin Molecule
- Biosynthesis of Heparin
- Physiological Heparin - its Function and Fate
- Mechanism of Heparin Rebound and Heparin-Protamine Interactions
- II. Methods for the Determination of Heparin
- Overview on Methods for the Determination of Heparin
- Control of Heparin Therapy by Measurement of the Antithrombin III-Heparin-Complex
- Determination of Heparin by a Fluorogenic Synthetic Substrate
- Properties of the Coatest ® Heparin As say
- A Sensitive Competitive Binding Assay for Heparin
- Determination of Low Dose Heparin Activities in Plasma
- Characterization of Heparin Preparations in Vivo by Different Test Systems
- Determination of Heparin and Fractionated Heparin with Different Molecular Weights
- III. Clinical Usage of Heparin
- Low Molecular Weight Heparin and the Prevention of Postoperative Deep Vein Thrombosis
- The Effect of Heparins on Platelet Release Reaction
- Characterization of a New Potent Heparin
- Side Effects of Heparin
- Role of Heparin-Like Molecules in Atherogenesis
- Unresolved Problems in the Use of Heparin
- IV. Experience with "Monitoring of Heparin Therapy"
- Heparin Treatment of Deep Venous Thrombosis: Correlation Between Clinical Effects and Heparin Assays
- Heparin-, Heparin Cofactor- and Platelet Factor 4 Plasma Levels Under Heparin Treatment
- Determination of Heparin, Partial Thromboplastin Time and Antithrombin III after Subcutaneous Heparin Administration
- Monitoring of Heparin During Extracorporal Circulation in Open Heart Surgery
- Chromogenic and Fluorogenic Assays - A Challenge for Conventional Monitoring of Heparin Therapy?
- V. Concluding Discussion
- Introduction
- Subject Index
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