Chemotherapy of gliomas : : Basic research, experiences and results / / ed. by C. Langmaid, D. Voth, P. Glees, P. Krauseneck.

• Superior document: Title is part of eBook package: De Gruyter DGBA Medicine and Life Sciences - <1990
• MitwirkendeR: Ahyai, A.,; Al-Hami, S.,; Ali-Osman, F.,; Alth, G.,; Altmannsberger, M.,; Ardenne, M. von,; Arnason, O.,; Bamberg, M.,; Beaney, R. P.,; Beneditsson, G.,; Berthelsen, A.,; Beuningen, D. van,; Bilzer, Th.,; Blech, M.,; Bloom, H. J. G.,; Blümel, G.,; Bogdahn, U.,; Bohl, J.,; Boker, D.K.,; Brandt, M.,; Brenner, R.,; Brock, M.,; Brooks, D. J.,; Bruggmoser, G.,; Brun, A.,; Budach, V.,; Busch, H.,; Chatel, M.,; Darcel, F.,; Dawson, K. B.,; Eggert, H. R.,; Elgen, K.,; Ernst, H.,; Falk, W.,; Fankhauser, R.,; Ferbert, A.,; Flament, H.,; Ganz, J.,; Garis, S. T . de,; Gerhard, L.,; Gilsbach, J.,; Glees, J. P.,; Glees, P.,; Gobel, H. H.,; Goebel, H.,; Grisold, W.,; Gronbsek, E.,; Gullotta, F.,; Gutjahr, P.,; Haase, J.,; Hagen, S.,; Halama, J.,; Halves, E.,; Hammer, R.,; Hassel, M. Ben,; Hatlevoll, R.,; Haßler, W.,; Heikkinen, M.,; Heiss, W.-D.,; Herbst, M.,; Herter, Th.,; Hildebrand, J.,; Hinkelbein, W.,; Holme, I.,; Holzgraefe, M.,; Huwel, N.,; Härders, A.,; Hürter, T.,; Hüwel, N.,; Ilsen, H. W.,; Jaksche, H.,; Jellinger, K.,; Jensen,,; Johansson, L.,; Jörg, J.,; Kappos, L.,; Kargl, W.,; Kass, W.,; Kefiel, G.,; Keim, H.,; Keiper, E.,; Kirsch, J .,; Kleihues, P.,; Klug, W.,; Kogelnik, H. D.,; Krauseneck, P.,; Kristiansen, K.,; Kuhnert, A.,; Kärcher, K. H.,; Lambretsen, E.,; Lederer, T.,; Leenders, K. L.,; Lindegaard, K. F.,; Lindgren, S.,; Lipecki, M.,; Littbrand, S.,; Luginbuhl, H.,; Mahlmann, E.,; Matheson, I.,; Mauersberger, W.,; Mella, O.,; Mennel, H. D.,; Mertens, H. G.,; Midholm, S.,; Moll, R.,; Mundinger, F.,; Màntylà, M.,; Müller, H.,; Nahser, H.C.,; Neiss, A.,; Nesbakken, R.,; Notter, G.,; Nystram, S.,; Oehr, P.,; Pecker, J.,; Pegg, A. E.,; Pobloth, A.,; Polar Salinas, E.,; Potthoff, P. C.,; Radebold, K.,; Rama, B.,; Rebmann, A.,; Richard, K. E.,; Richter, E.,; Ringkjob, R.,; Roggendorf, W.,; Rosenblum, M. L.,; Rosengren, B.,; Rupniak, H. T. R.,; Rygard, J.,; Scarabin, J. M.,; Schandelmaier, C.,; Scheef, W.,; Schlechtingen, J.,; Schlie, M.,; Schmidt, M.,; Schwarz, M.,; Seeger, W.,; Sehested, P.,; Seybold, D.,; Spaar, F.W.,; Spoerri, O.,; Sprich, M.,; Spànnare, B.,; Stadler, B.,; Stavrou, D.,; Stochdorph, O.,; Streffer, C.,; Szepesi, T.,; Sàterborg, N. E.,; Taskinen, P.,; Thomas, D. G. T.,; Torvik, A.,; Trappe, A.,; Vandevelde, M.,; Vole, D.,; Voth, D.,; Wannenmacher, M.,; Weigel, K.,; Weiss, R.,; Wessely, P.,; Wiestler, O. D.,; Wilhelm, H.,; Wober, G.,; Wöber, G.,; Zeile, G.,; Zänker, K. S.,
• HerausgeberIn: Glees, P.,; Krauseneck, P.,; Langmaid, C.,; Voth, D.,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2019]; ©1984
• Year of Publication: 2019
• Edition: Reprint 2019
• Language: English
• Physical Description: 1 online resource (439 p.)

Table of Contents

Frontmatter -- Foreword -- Contents -- I. Special and comparative pathology of the gliomas – experimental findings -- Classification of supratentorial gliomas -- Remarks on classification and "grading" (Brief communication) -- Problems in the histological grading of human gliomas -- Comparative aspects of spontaneous gliomas in animals (Brief communications) -- Cell-mediated immune response during progressive glioma growth -- Application of immunohistological techniques to the diagnosis of gliomas -- Flow cytometry and micronucleus formation in brain tumours -- Comparative impulsecytophotometric DNA investigations of glioblastomas, oligodendrogliomas and astrocytomas -- Repair of O6-alkylguanine in cellular DNA: significance for tumour induction and chemotherapy -- Escape phenomenon of glioma cells to allogenic lymphocytes and rhythmically altered protein synthesis encoded by signal transfer -- Microscopical investigations on cell death in experimental gliomas in rats -- Human glioma xenografts in nude mice: experimental model for pre-clinical chemo-radiotherapy studies -- Mononuclear infiltrates in human brain tumours – possible morphological equivalence of an immunological defence reaction -- II. General and specialised diagnostic methods for intrinsic brain tumours -- Correlation between grade of malignancy of gliomas and their computer tomographic density values -- Cerebral gliomas studied with positron emission tomography -- Remarks on the follow-up of cerebellar astrocytomas (Brief communication) -- Cerebral cysticercosis – a contribution to the differential diagnosis of supratentorial and infratentorial gliomas -- Measurement of intracranial pressure. Technique and indications -- Intracranial pressure monitoring in postoperative treatment of supratentorial and infratentorial gliomas (Brief communication) -- EEG, SEP and VEP examinations during the treatment of malignant gliomas -- CEA and TPA in plasma and cerebrospinal fluid of patients with intracranial tumours -- Sensitivity of human malignant brain tumours to chemotherapeutic agents as detected by the pro-assay: preliminary results of an in vivo/in vitro correlation -- III. Principles of operative treatment and radiation therapy -- Changes induced in anaplastic gliomas and brain tissue as a result of treatment -- Microsurgical management of gliomas -- Management of malignant gliomas. A ten year survey at the Neurosurgical Department of Rennes -- Re-operating on malignant gliomas: Indications, problems and results -- The Ommaya reservoir and its significance for intrathecal cytostatic treatment. Surgical aspects and complications -- The significance of age as a factor in the prognosis of surgically treated cerebral gliomas (Brief communication) -- Quality of life following microsurgical removal of glioblastomas (Brief communication) -- Neuropsychological studies under the therapy of malignant gliomas -- Quality of life in patients with malignant brain tumours -- Postoperative rapid course irradiation of the glioblastoma -- CT-stereotactic interstitial irradiation therapy of non resectable and reentrant intracranial tumour in children and adolescents -- Treatment of astrocymatomas grade DI and IV with high-dose irradiation and misonidazole: preliminary report -- Reflections on the radiation treatment of gliomas -- Therapeutic results in malignant gliomas with special respect to radiotherapy -- Pseudo-recurrence in malignant brain tumours -- Histological-cytological study of the effects of misonidazole and some related substances on the nervous system -- Local, intratumoral chemotherapy of brain gliomas in the rat, using adriamycin – a preliminary report -- IV. Chemotherapy: Basic principles, experiences, results and alternative procedures -- Principles of cancer treatment with cytostatic agents (Brief communication) -- Chemotherapy of malignant gliomas – present state of treatment (Brief communication) -- Chemotherapy of malignant supratentorial gliomas in adult: a ten-year experience of the EORTC Brain Tumour Group -- Characterization of human malignant brain tumour cells in vitro and comparison of three different in vitro assays to determine their sensitivity to BCNU -- Combined modality treatment of operated astrocytomas grade 3–4. A prospective and randomized study of misonidazole and radiotherapy with two different radiation schedules and subsequent CCNU chemotherapy -- Chemotherapy of gliomas in adults and of medulloblastoma in children -- Combined radiation and polychemotherapy (COMP) in the postoperative treatment of high-grade supratentorial gliomas -- Combined chemotherapy of inoperable and operable malignant gliomas -- Mono-treatment of malignant glioma with a derivate of nitrosourea, ACNU (first results) -- Retrospective study on the effect of CCNU and radiotherapy in 44 patients with malignant glioma -- The treatment of brain tumours and brain metastases with a combination of Ifosfamid, BCNU and radiotherapy – preliminary results (Brief communication) -- Intra-arterial therapy of malignant gliomas with ACNU and BCNU in combination with phénobarbital protection (preliminary results) -- Critical analysis of therapy in long-term surviving patients with glioblastoma multiforme -- Preoperative chemo- and/or radiotherapy: its possible role in the treatment of malignant brain gliomas (Brief communication) -- The present state of development of multistage treatment of cancer. Fundamental principles of the two-stage regional hyperthermia technique, using the "Selectotherm" procedure, as well as the heat sensitisation of cancer tissue by means of hyperglycaemia (Brief communication) -- Hyperthermia-radiotherapy of the gliomas – a critical report -- Planning, realization and evaluation of clinical trials: some statistical aspects -- V. Summary of the present state of chemotherapy of the supratentorial gliomas -- List of contributors -- Author's index -- Subject index