The Target of Penicillin : : The Murein Sacculus of Bacterial Cell Walls Architecture and Growth. Proceedings International FEMS Symposium Berlin (West), Germany, March 13–18, 1983 / / ed. by H. Labischinski, J. V. Höltje, R. Hakenbeck.

• Superior document: Title is part of eBook package: De Gruyter DGBA Physical Sciences <1990
• MitwirkendeR: Aran, V.,; Arán, Vicente,; Ayala, J. A.,; Baddiley, James,; Barbas, Julio A.,; Bardin, C.,; Barnickel, Gerhard,; Barrett, John,; Barrie Ward, J.,; Bender, Gary R.,; Berenguer, José,; Beveridge, T.J.,; Billot-Klein, Danielle,; Blundell, J. Keith,; Bläsi, U.,; Blümel, Peter,; Botta, Giuseppe A.,; Bradaczek, Hans,; Brandt, Cyrille,; Braun, V.,; Braun, Volkmar,; Briese, Thomas,; Briquet, J.-J.,; Broome-Smith, J.,; Broome-Smith, Jenny,; Brown, D. F. J.,; Buchanan, Christine E.,; Burghaus, Petra,; Burman, Lars G.,; Canepari, P.,; Canepari, Pietro,; Carstensen, Edwin L.,; Chapman, Stephen J.,; Charlier, Paulette,; Child, Sally Z.,; Costa, Alessandro,; Coyette, J.,; Criegee, Hildegard,; Daneo-Moore, L.,; Daneo-Moore, Lolita,; Dideberg, Otto,; Dive, Georges,; Dolinger, David,; Dreher, R.,; Drews, Gerhart,; Dusart, Jean,; Edelman, A.,; Edelman, Alex,; Ellerbrok, Heinz,; Ferrero, M.,; Fischer, Erwin,; Fischer, Helene,; Fischer, Werner,; Flouret, B.,; Folkening, W. Joseph,; Fontana, R.,; Fontana, Roberta,; Formanek, Helmut,; Fouts, Rebecca L.,; Franken, Norbert,; Frère, Jean-Marie,; Fréhel, Claude,; Geisen, R.,; Ghuysen, J.-M.,; Ghuysen, Jean-Marie,; Gibson, Carolyn W.,; Giesbrech, Peter,; Giesbrecht, Peter,; Ginsburg, Isaac,; Glauner, B.,; Glauner, Bernd,; Gmeiner, Jobst,; Goodell, E. Wm.,; Gutmann, Laurent,; Hakenbeck, Regine,; Hammes, Walter P.,; Hara, Hiroshi,; Harrington, Charles E.,; Hayes, Michael V.,; Heijenoort, J. van,; Heijenoort, Yveline van,; Henning, Susanne,; Henrich, B.,; Henrich, Bernhard,; Higgins, Michael L.,; Hirota, Y.,; Holtje, J. -V.,; Höltje, J. -V.,; Höltje, J.-V.,; Höltje, Joachim-Volker,; Inbar, Livia,; Ishiguro, Edward E.,; Ishino, F.,; Johannsen, Lars,; Joris, Bernard,; Jürgens, Uwe Johannes,; Kalomiris, E.,; Kandier, Otto,; Karamata, Dimitri,; Kasra, Rouha,; Kawamura, Takashi,; Kelly, Judith A.,; Kersten, Thomas,; Koch, Arthur L.,; Koch, Hans Uwe,; Kraus, W.,; Krüger, Dominique,; Kwa, Elli,; Labischinski, Harald,; Lahav, Meir,; Lamotte-Brasseur, Josette,; Lapidot, Aviva,; Laynez, Jose,; Lederer, Edgar,; Leduc, Mireille,; Leps, Bernd,; Leyh-Bouille, Mélina,; Lleὸ, Maria del Mar,; Lubitz, Werner,; Lubitzt, W.,; Markiewicz, Zdzislaw,; Marquis, Robert E.,; Maruyama, J.N.,; Maruyama, T.,; Matsuhashi, M.,; Mengin-Lecreulx, D.,; Mett, H.,; Metz, Renate,; Meyer, P. D.,; Meyer, P.D.,; Mirelman, D.,; Mollner, Stefan,; Monod, Michel,; Montilla, Juan-Carlos,; Morioka, Hiroyuki,; Nakagawa, J.,; Nanninga, N.,; Nanninga, Nanne,; Naumann, Dieter,; Nederlof, Petra M.,; Neuhaus, F.,; Nguyen-Distèche, Martine,; Nöthling, Roswitha,; Olijhoek, A. J. M.,; Park, James T.,; Park, W.,; Parquet, C.,; Pedro, M. A. de,; Pedro, Miguel A. de,; Pelzer, Helmut,; Perkins, Harold R.,; Petersen, Bruce H.,; Phadke, Kalindi,; Plapp, R.,; Plapp, Roland,; Pooley, Harold M.,; Pooley, Harold,; Pucci, M.,; Qoronfleh, M. Walid,; Raible, Angelika,; Rao, V.S.R.,; Reinicke, Bernhard,; Reusch, Victor M.,; Reynolds, P. E.,; Reynolds, Peter E.,; Rodriguez-Tebar, A.,; Rodriguez-Tébar, Alfredo,; Rodríguez-Tébar, Alfredo,; Rogers, H. J.,; Rosa, E. J. de la,; Rosenthal, Raoul S.,; Rönspeck, Wolfgang,; Said, I. Mohamed,; Salton, Milton R. J.,; Sarnow, Elke,; Satta, G.,; Satta, Giuseppe,; Schleifer, Karl H.,; Schleifer, Karl Heinz,; Schrinner, E.,; Schwarz, U.,; Schwarz, Uli,; Seeger, K.,; Seidl, Peter H.,; Shockman, Gerald D.,; Sinha, R.,; Somze, A.,; Sowell, Margaret O.,; Spratt, B. G.,; Spratt, Brian G.,; Stoker, N. G.,; Strominger, Jack L.,; Sudo, A.,; Suzuki, Hideho,; Swim, Scott C.,; Tamaki, S.,; Thurman, P. F.,; Tomasz, Alexander,; Tomioka, S.,; Ueda, Taro,; Vazquez, D.,; Vázquez, David,; Wecke, Jörg,; Weckesser, Jürgen,; Wientjes, F. B.,; Wilkinson, Brian J.,; Williamson, Russell,; Wolf, Gudrun,; Wouters, J. T. M.,; Wouters, J.T.M.,; Wyke, Anne W.,; Yamamoto, A.,; Zito, E.,; de Boer, Piet,; den Blaauwen, Tanneke,; van Heijenoort, Jean,; ßarnickel, Gerhard,
• HerausgeberIn: Hakenbeck, R.,; Höltje, J. V.,; Labischinski, H.,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2019]; ©1983
• Year of Publication: 2019
• Edition: Reprint 2019
• Language: English
• Physical Description: 1 online resource (663 p.) :; Num. figs.

Table of Contents

Frontmatter -- Preface -- CONTENTS -- CONTRIBUTORS AND PARTICIPANTS -- INTRODUCTION -- THE BACTERIAL CELL WALL - STRUCTURE AND FUNCTION -- PART I. PRIMARY AND THREE DIMENSIONAL STRUCTURE OF MUREIN -- PRIMARY STRUCTURES OF MUREIN AND PSEUDOMUREIN -- STRUCTURE OF THE PEPTIDOGLYCAN OF THE CYANOBACTERIUM SYNECHOCYSTIS PCC 6714 -- CHARACTERIZATION OF MUROPEPTIDES RELEASED FROM MUREIN OF CAULO-BACTER CRESCENTUS BY ENDO-N-ACETYLMURAMIDASE -- THE ANALYSIS OF MUREIN COMPOSITION WITH HIGH-PRESSURE-LIQUID CHROMATOGRAPHY -- THE ANIONIC NATURE AND SOME PERMEABILITY CHARACTERISTICS OF MUREIN -- ELECTROCHEMICAL AND MECHANICAL INTERACTIONS IN BACILLUS SPORE AND VEGETATIVE MUREINS -- THE STATE OF ORDER OF BACTERIAL PEPTIDOGLYCAN -- A THREE DIMENSIONAL MODEL OF THE MUREIN LAYER EXPLAINING ONE STEP OF ITS BIOSYNTHESIS BY SELF-ASSEMBLY -- COMPUTER AIDED MOLECULAR MODELLING OF THE THREEDIMENSIONAL STRUCTURE OF BACTERIAL PEPTIDOGLYCAN -- COMPARISON BETWEEN THE SUGAR CHAIN CONFORMATION IN MUREIN AND PSEUDOMUREIN -- THE CONFORMATIONAL BEHAVIOUR OF THE PEPTIDE PART OF MUREIN - AN INFRARED AND RAMAN SPECTROSCOPIC STUDY -- DYNAMIC ASPECTS OF BACTERIAL CELL WALLS PROBED BY IN VIVO 15N NMR -- A NOVEL AND RAPID METHOD FOR IDENTIFYING IMPORTANT CELL WALL PARAMETERS: FOURIER-TRANSFORM INFRARED SPECTROSCOPY -- CALORIMETRIC STUDIES ON THE BINDING OF VANCOMYCIN - LIKE ANTIBIOTICS TO PEPTIDOGLYCAN -- PART II. MODELS FOR THE GROWTH OF THE MUREIN SACCULUS -- THE SHAPES OF GRAM-NEGATIVE ORGANISMS: VARI ABLE-T MODELS -- MUREIN RING STRICTURE AND BIOSYNTHESIS IN GRAM-NEGATIVE BACTERIA: SOME TENTATIVE CONTEMPLATIONS -- REGULATION OF THE INITIA1ICN AND OCMPLETICK OF ENVELOPE GRCWIH SITES IN STREPTOCOCCUS FAECIUM (ATCC 9790) -- A NEW MODEL FDR GROWTH OF THE MUREIN SACCULUS -- PEPTIDE CROSSBRIDGES IN THE MUREIN OF ESCHERICHIA COLI ARE BROKEN AND REFORMED AS THE BACTERIUM GROWS -- A NOVEL HYPOTHESIS TO EXPLAIN REGULATION OF THE MUREIN SACCULUS SHAPE -- GENERAL PROPERTIES OF TEMPERATURE-SENSITIVE CELL DIVISION MUTANTS OF STREPTOCOCCUS FAECIUM -- PREMATURE DIVISION IN ESCHERICHIA COLI IN THE PRESENCE OF TRIS-EDTA -- PART III. FUNCTION OF MUREIN HYDROLASES AND CONTROL OF MUREIN DEGRADATION -- MUREIN HYDROLASES - ENZYMES IN SEARCH OF A PHYSIOLOGICAL FUNCTION? -- THE AUTOLYTIC SYSTEM OF STREPTOCOCCUS FAECIUM -- INTERACTION BETWEEN CHOLINE AND THE N-ACETYL-MURAMYL-L-ALANINEAMIDASE OF STREPTOCOCCUS PNEUMONIAE -- THE INFLUENCE OF LIPOTEICHOIC ACIDS ON THE AUTOLYTIC ACTIVITY OF STAPHYLOCOCCUS AUREUS -- COENZYME A-GLUTATHIONE DISULFIDE: AN ENDOGENOUS INHIBITOR OF THE LYTIC ENZYMES IN ESCHERICHIA COLI -- AUTOLYSIS OF ESCHERICHIA COLI INDUCTION AND CONTROL -- EXPRESSION OF ØX174 LYSIS GENE CLONED INTO DIFFERENT PLASMIDS -- LOCALISATION OF THE BACTERIOPHAGE ØX1.74 LYSIS GENE PRODUCT IN THE CELL ENVELOPE OF ESCHERICHIA COLI -- INDUCTION OF CELL LYSIS BY MECILLINAM PLUS NOCARDICIN A: ISOLATION AND PROPERTIES OF A TOLERANT MUTANT -- INCREASED WALL AUTOLYSIS AND DECREASED PEPTIDOGLYCAN CROSSLINKING IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS GROWN IN THE PRESENCE OF METHICILLIN -- MORPHOLOGICAL STUDY OF THERMOSENSITIVE LYSIS MUTANTS OF BACILLUS SUBTILIS -- CHARACTERISTICS OF TOLERANT GROUP A STREPTOCOCCI -- CELL WALL METABOLISM IN LYT-MUTANTS OF BACILLUS SUBTILIS -- RESTORATION OF PENICILLIN-DAMAGED CELL WALLS BY DE NOVO MUREIN SYNTHESIS AND SUCCESSIVE MUREIN DEGRADATION IN STAPHYLOCOCCI, REVEALING A HITHERTO UNKNOWN MECHANISM OF PENICILLIN ACTION: BLOCKAGE OF AUTOLYTIC WALL PROCESSES BY PENICILLIN -- β-LACTAM ANTIBIOTICS DO NOT TRIGGER THE ACTIVITIES OF AUTOLYSINS IN ETHER PERMEABILIZED ESCHERICHIA COLI -- O-ACETYLATION AND HYDROLASES OF GONOCOCCAL PEPTIDOGLYCAN -- ACETYLATION IN DIFFERENT PHASES OF GROWTH OF STAPHYLOCOCCI AND THEIR RELATION TO CELL WALL DEGRADABILITY BY LYSOZYME -- EFFECT OF PENICILLIN"AND CHLORAMPHENICOL-TREATMENT ON THE MUREIN IN STREPTOCOCCUS PNEUMONIAE : ALTERATION IN STRUCTURE AND SUSCEPTIBILITY TO MUREIN HYDROLASES -- MICROCALORIMETRIC AND ELECTRON MICROSCOPIC INVESTIGATION ON STAPHYLOCOCCI BEFORE AND AFTER TREATMENT WITH PENICILLIN AND CHLORAMPHENICOL AND THEIR COMBINATIONS -- CORRELATION OF CELL WALL TURNOVER AND AUTOLYTIC ACTIVITY IN FLA AND SUPERMOTILE MUTANTS OF BACILLUS SUBTILIS -- B. SUBTILIS W23/168 RECOMBINANTS WITH HYBRID CELL WALLS AND PHAGE RESISTANCE PATTERNS -- PART IV. BIOLOGICAL PROPERTIES AND MEDICAL ASPECTS OF MUREIN -- IMMUNOMODULATING PROPERTIES OE NATURAL AND SYNTHETIC MUROPEPTIDES -- THE IMMUNOCHEMISTRY OF PEPTIDOGLYCAN -- A NEW MUREIN HYDROLASE IN HUMAN SERUM -- LYSOZYME-RESISTANT Q-ACETYLATED PEPTIDOGLYCAN OF NEISSERIA GONORRHOEAE : STRAIN VARIATION, RESISTANCE TO HUMAN PEPTIDOGLYCAN HYDROLASES, AND PATHOBIOLOGICAL PROPERTIES -- THE INFLUENCE OF DIFFERENT ANTIBIOTICS ON THE DEGREE OF O-ACETYLATION OF STAPHYLOCOCCAL CELL WALLS -- CELL WALL DEGRADATION OF STAPHYLOCOCCUS AUREUS BY AUTOLYSINS AND LYSOZYME -- CELL WALL DEGRADATION OF ANTIBIOTIC-TREATED STAPHYLOCOCCI UNDER PHAGOCYTE-SPECIFIC CONDITIONS: Distinction between Penicillin-Induced Lytic Effects and Wall Alterations Caused by Anticoagulants -- INDUCED AUTOLYTIC WALL PROCESSES IN HEAT-INACTIVATED STAPHYLOCOCCUS AUREUS -- CATIONIC POLYELECTROLYTES ACTIVATE AUTOLYTIC WALL ENZYMES IN STAPHYLOCOCCUS AUREUS: Modulation by anionic polyelectrolytes in relation to the survival of bacterial constituents in tissues -- PART V. STRUCTURE AND FUNCTION OF PENICILLIN-BINDING PROTEINS -- PENICILLIN BINDING PROTEINS AS TARGETS OF THE LETHAL EFFECTS OF β-LACTAM ANTIBIOTICS -- BINDING SPECIFICITIES OF PENICILLIN BINDING PROTEINS - A CONFORMATIONAL APPROACH -- THE ACTIVE SITES OF THE D-ALANYL-D-ALANINE-CLEAVING PEPTIDASES -- X-RAY STRUCTURE OF A PENICILLIN TARGET ENZYME -- THE FINE ARCHITECTURE AND FUNCTION OF THE GENE CODING FOR PBP-3 OF ESCHERICHIA COLI -- SEQUENCE OF PENICILLIN-BINDING PROTEIN 5 OF ESCHERICHIA COLI -- PURIFICATION AND IDENTIFICATION OF THE Pseudomonas aeruginosa DD-ENDOPEPTIDASE AS A PENICILLIN-BINDING PROTEIN -- PURIFICATION OF PENICILLIN BINDING PROTEINS FROM STREPTOCOCCUS PNEUMONIAE -- CHARACTERIZATION OF PENICILLIN BINDING PROTEINS FROM STREPTOCOCCUS PNEUMONIAE BY PROTEOLYSIS -- DISTRIBUTION OF PENICILLIN-BINDING PROTEINS WITHIN THE CELL ENVELOPE OF Escherichia coli -- LABELLING AND CROSS-LINKING OF E. COLI PBPs WITH BIS-B-LACTAM AND PHOTOREACTIVE DERIVATIVES OF B-LACTAM ANTIBIOTICS -- TOPOLOGICAL INTERRELATION OF PENICILLIN-BINDING PROTEINS IN E. COLI - A STUDY USING CLEAVABLE CROSS-LINKERS -- ELECTROFOCUSING OF INTEGRAL BACTERIAL MEMBRANE PROTEINS WITH SPECIAL REGARD TO PBPs. -- CHARACTERIZATION OF THE CHANGES IN PENICILLIN-BINDING PROTEINS THAT OCCUR DURING SPORULATION OF BACILLUS SUBTILIS -- PATTERN OF PENICILLIN-BINDING PROTEINS DURING THE LIFE CYCLE OF ESCHERICHIA COLI -- GROWTH DEPENDENT MODIFICATIONS OF THE PENICILLIN BINDING PROTEINS OF Escherichia coli : INFORMATION SUPPORTING THE GENERALITY OF THE PROCESS AND THE MULTIPLICITY OF MECHANISMS -- RECOMBINANT PLASMIDS CARRYING PENICILLIN-BINDING PROTEIN/CELL SHAPE GENES FROM THE lip-leuS REGION OF THE ESCHERICHIA COLI CHROMOSOME -- SOME ASPECTS OF THE MECHANISM OF EXPRESSION OF PBP 3 IN E.coli -- THE INTERDEPENDENCE OF BACTERIAL SHAPE AND SIMULTANEOUS BLOCKING OF PBP 2 AND 3 IN ESCHERICHIA COLI SP 45 AND ESCHERICHIA COLI SP 63 -- BENZYLPENICILLIN-RESISTANT MUTANTS OF CLOSTRIDIUM PERFRINGENS -- STUDIES OF ß-LACTAM RESISTANCE IN STREPTOCOCCUS FAECIUM -- BIOSYNTHESIS OF MUREIN (PEPTIDOGLYCAN) -- ENZYMATIC SYNTHESIS OF PEPTIDOGLYCAN-CROSSBRIDGES IN E. COLI -- NEW INSIGHTS IN THE PROCESS OF IN VITRO MUREIN SYNTHESIS IN E. COLI REVEALED BY MUREIN-ANALYSIS WITH HIGH-PRESSURE-LIQUIDCHROMATOGRAPHY -- PENICILLIN-BINDING PROTEINS AND PEPTIDOGLYCAN BIOSYNTHESIS IN BACILLUS MEGATERIUM -- FUNCTION OF PENICILLIN-BINDING PROTEIN 3 IN STREPTOCOCCUS FAECIUM -- THE ROLE OF A PROTEIN THAT BINDS PENICILLIN WITH SLOW KINETICS IN PHYSIO LOGY AND RESPONSE TO PENICILLIN OF STREPTOCOCCUS FAECIUM ATCC 9790 -- TRANSPEPTIDATION IN STAPHYLOCOCCUS AUREUS WITH INTRINSIC RESISTANCE TO ß-LACTAM ANTIBIOTICS ("METHICILLIN RESISTANCE") -- PENICILLIN-SENSITIVE ENZYMES IN STAPHYLOCOCCUS AUREUS -- VI. BIOSYNTHESIS OF MUREIN -- PEPTIDOGLYCAN BIOSYNTHESIS : CONTROL OF PRECURSOR SYNTHESIS AND INTERMEDIATES IN ASSEMBLY -- CYTOPLASMIC STEPS OF PEPTIDOGLYCAN SYNTHESIS IN E.

coli K 12 -- EFFECT OF DRUGS ON THE FORMATION AND STRUCTURE OF INTERMEDIATES OF ESCHERICHIA COLI MUREIN BIOSYNTHESIS -- THE EFFECT OF 6-LACTAM ANTIBIOTICS ON MUREIN SYNTHESIS IN ETHER TREATED ESCHERICHIA COLI -- COMPARISON OF THE EFFECTS ON MUREIN SYNTHESIS OF ß-LACTAM ANTIBIOTICS AND D-AMINO ACIDS -- Hildegard Criegee and Walter P. Hammes -- BIOSYNTHESIS OF PEPTIDOGLYCAN IN GAFFKYA HOMARI: Processing of nascent glycan by reactivated membranes -- THE INHIBITION OF IN VITRO SYNTHESIS OF MUREIN IN GAFFKYA HOMARI BY MONOCYCLIC ß-LACTAM ANTIBIOTICS NOCARDICIN B,E AND AZTHREONAM -- PEPTIDOGLYCAN SYNTHESIS IN VITRO BY PARTICULATE PREPARATION FROM Streptococcus sangui s 34 -- SYNTHESIS OF PEPTIDOGLYCAN FROM EXTEENALLY SUPPLIED PBECUESOES BY PARTLY AUTOLYSED CELLS OP Bacillus subtilis W23 -- O-ACETYLATION OF MURAMIC ACID, BIOSYNTHESIS OF MUREIN AND THE EFFECT OF PENICILLIN G IN VIVO IN SYNCHRONIZED CELLS OF PROTEUS MIRABILIS -- PEPTIDOGLYCAN SYNTHESIS AND TURNOVER IN BACILLUS SUBTILIS -- POTENTIAL SITES FOR THE COORDINATE CONTROL OF MUREIN AND TEICHOIC ACID BIOSYNTHESIS IN S. PNEUMONIAE -- MECHANISM OF STRINGENT CONTROL OF PEPTIDOGLYCAN SYNTHESIS IN ESCHERICHIA COLI -- INTERRELATIONSHIPS BETWEEN WALL AND MEMBRANE BIOSYNTHESIS -- FUNCTIONAL DOMAINS OF COLICIN M -- Author Index -- Subject Index -- Backmatter