Proteases of Retroviruses : : Proceedings of the Colloquium C 52, 14th International Congress of Biochemistry, Prague, Czechoslovakia, July 10–15, 1988 / / ed. by Vladimír Kostka.

• Superior document: Title is part of eBook package: De Gruyter DGBA Reference Works <1990
• MitwirkendeR: Adachi, M.,; Billich, S.,; Bláha, I.,; Brenner, J.,; Bu, M.,; Danho, W.,; Dayton, Brian D.,; Debouck, Christine,; Everitt, L.,; Farmerie, W. G.,; Feng, Ya-Xiong,; Foundling, S. I.,; Fusek, M.,; Gorniak, Joseiina,; Graves, M. C.,; Grice, S. Le,; Hatanaka, M.,; Hatfield, Dolph L.,; Helm, K. von der,; Hutchison, C. A.,; Ikai, A.,; Ikawa, Y.,; Ikuta, K.,; Jaskolski, M.,; Kaprálek, F.,; Katoh, I.,; Knoop, M. T.,; Konvalinka, J.,; Korant, B. D.,; Kostka, V.,; Kotier, M.,; Lee, Byeong J.,; Leis, J.,; Leuthardt, A.,; Levin, Judith G.,; Lim, J. J.,; Loeb, D. D.,; Luftig, R. B.,; Meek, Thomas D.,; Metcalf, Brian W.,; Miedel, M. C.,; Miller, M.,; Mills, J.,; Moelling, K.,; Moore, Michael L.,; Mous, J.,; Nalin, C. M.,; Nam, S. H.,; Oroszlan, Stephen,; Pal, Ranajit,; Pan, Y.-C. E.,; Pavlíčková, L.,; Pearl, Laurence H.,; Pichová, I.,; Rao, M.,; Rein, Alan,; Reutener, S.,; Rosenberg, Martin,; Sarngadharan, M. G.,; Schmidt, H.,; Sedláček, J.,; Seelmeier, S.,; Souček, M.,; Stoller, T. J.,; Strickler, James E.,; Swanstrom, R.,; Trávníček, M.,; Velek, J.,; Wlodawer, A.,; Yamamoto, N.,; Yoshinaka, Y.,; Zehnle, R.,; Zicopoulos, M. A.,; Štrop, P.,
• HerausgeberIn: Kostka, Vladimír,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2019]; ©1989
• Year of Publication: 2019
• Edition: Reprint 2019
• Language: English
• Physical Description: 1 online resource (XI, 206 p.) :; Num. figs.

Table of Contents

Frontmatter -- Preface -- Acknowledgments -- Contents -- Introduction -- Characteristics of Viral Proteases -- Retrovirus Gene Products and Their Processing -- Morphogenesis of Retroviruses in the Presence and Absence of Protease Inhibitors -- Processing of the Envelope and Core Proteins of Human Immunodeficiency Virus Type 1 -- Biosynthesis and Biochemical Characteristics of Retroviral Proteases -- Mechanisms of Ribosomal Frameshifting for Synthesis of the Protease in HIV and other Retroviruses and the Possible Use of Hypomodified tRNAs in the Frameshift Event -- Biochemical characterization of retrovirus protease -- Bacterial Expression, Processing and Characterization of Recombinant Retroviral Proteases -- Expression and Processing of p15gag Protease of Myeloblastosis Associated Virus in E. coli -- Isolation and Characterization of p15gag Protease of Myeloblastosis Associated Virus Expressed in E. coli -- Biochemical Characterization of HIV-1 Protease Purified from a Bacterial Expression System -- Expression and Characterization of Human Immunodeficiency Virus-1 Protease -- Mutational Analyses of Retroviral Proteases -- Analysis of HIV-1 Protease Via Deletion and In Vitro Mutagenesis Studies -- In Vitro Mutation of the Asp-25 Blocks and Pepstatin A Inhibits the Activity of the Human Immunodeficiency Virus (HIV) Encoded Protease -- Mutational Analysis of the HIV-1 Protease: Importance for Function of Sequences within and Flanking the Protease Domain -- Synthesis and Activity of HTLV-1 Protease and its Muteins -- Structure, Function and Evolution of Retroviral Proteases -- Activation and Regulation of Avian Sarcoma Leukemia Virus (ASLV) Protease -- Characterization of pl5 Protease of Myeloblastosis Associated Virus by Specificity and Inhibition Studies -- Characterization of HIV-1 Protease Substrate Specificity by Use of Synthetic Peptides -- Preliminary crystallographic investigation of a protease from rous sarcoma virus -- Structure and Evolution of Retroviral Proteinases -- Author Index -- Abbreviations -- Subject Index -- Backmatter