Culture Techniques : : Applicability for Studies on Prenatal Differentiation and Toxicity. Fifth Symposium on Prenatal Development, May 1981, Berlin / / Diether Neubert, Hans J. Merker, J. Klein-Friedrich, R. Kreft.
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Superior document: | Title is part of eBook package: De Gruyter DGBA Medicine and Life Sciences - <1990 |
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HerausgeberIn: | |
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Place / Publishing House: | Berlin ;, Boston : : De Gruyter, , [2019] ©1981 |
Year of Publication: | 2019 |
Edition: | Reprint 2019 |
Language: | French |
Online Access: | |
Physical Description: | 1 online resource (621 p.) :; Num. figs. |
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Other title: | Frontmatter -- Dedication -- Preface -- Table of Contents -- Introduction / I. Studies on Whole-Embryo Culture -- Differentiation of Embryonic Tissues in Whole-Embryo Cultures as Compared to the Development In Vivo / The Differentiation Between Teratogenic Action on Mother, Fetal Membranes and Embryos Using the Whole-Embryo Culture Method / Trypan Blue Teratogenesis in the Rat In Vitro / Studies on Embryotoxic Effects of Thallium Using the Whole-Embryo Culture Technique / Evaluation of Serum Teratogenic Activity Using Rat Embryo Cultures / Regulation of Mouse Embryogenesis by Exogenous Growth Factors / Preliminary Communication on the Feasibility of Culturing Whole Embryos in a Chemically Defined Medium / In Vitro Development of the Heart Under Influence of Retinole Acid / II. Studies on Organ Cultures -- A. Differentiation of the Skeleton (predominantly Extremities) -- Simulation of Limb Bud Skeletogenesis In Vitro / Comparison of the Differentiation of Muscle and Connective Tissue of Mouse Limb Buds in Culture and In Vivo: A Morphological Study by Indirect Immunofluorescence / Quantification of Collagen Types I and II in Mouse Limbs during Differentiation In Vitro and In Vivo / Feasibility of Storing Embryonic Tissues for Subsequent Use in Organ Culture / Limb Bud Organ Cultures from Mouse Embryos after Apparent Induction of Monooxygenases In Utero. Effects of Cyclophosphamide, Dimethylnitrosamine and Some Thalidomide Derivatives / On the Significance of Ascorbate and of Cysteine on Differentiation of Limb Buds in Organ Culture / Effects of Some "Indirectly" Alkylating Agents on Differentiation of Limb Buds in Organ Culture / Comparison of Effects on Limb Development In Vivo and In Vitro Using Methyl(acetoxymethyl)nitrosamine / Development of Limb Buds in Organ Culture: Examination of Hydroxyurea Enhancement of Bromodeoxyuridine Toxicity Using Image Analysis / Biochemical Characterization of Mouse Hereditary Chondrodystrophies in Organ Culture / Effect of Teratogens on Human Embryonic Skeletal Tissue In Vitro / Aspirin Induced Polydactyly in Rats Mediated by Inhibition of Prostaglandin Synthesis / B. Differentiation of other Organ Anlagen (kidneys, lungs, heart, prostate gland, haematopoetic system, and intestine) -- The Developing Kidney as a Model System for Normal and Impaired Organogenesis / The Embryonic Lung as In Vitro Model for Testing Teratogenic Substances / The Toxic Effects of Metal Dusts on Human Foetal Lungs In Vitro / Effects of Substances Influencing Glycosaminoglycan Synthesis on Lung Development in Culture / Effects of L-azetidine-2-carboxylic Acid and ß-D-xylosides on Lung Development In Vitro / Interaction of Epithelium and Mesenchyme in the Induction of Foetal Rat and Mouse Prostate Glands by Androgens in Organ Culture / In Vivo and In Vitro Assays of Trisomie Cells Isolated from the Fetal Organism or Rescued by Transfer to Non-Trisomic Hosts / Effects of Gliadin-derived Peptides from Bread and Durum Wheat on Small Intestine Cultures from Rat Fetus and Coeliac Children / III. Studies on Preimplantation Embryos -- Differential Adhesiveness as a Mechanism of Cell Allocation to Inner Cell.Mass and Trophectoderm in the Mouse Blastocyst / Inefficient Capacity for Oxidative Phosphorylation of the Trophoblast as a Cause of Delayed Implantation in the Mouse / Influence of Micromanipulation of Ova on the Postnatal Development of Mice (AKR) / Investigations on the Mechanism of Action and on the Pharmacokinetics of Cyclophosphamide Treatment during the Preimplantation Period in the Mouse / Benzo(a)pyrene Metabolism in Early Mouse Embryos / IV. Studies on Cell and Tissue Cultures -- Influence of Different Antisera on Mouse Epiphyseal Chondrocytes in Monolayer Culture / Cell Movement during Blastema Formation. Effect of Cytochalasin B on Cartilage Development In Vitro / Cell-Substrate Adhesion of Fibroblast-like Cells Under Different In Vitro Conditions. A Scanning and Transmission Electron-Microscopic Study / Development of Cytochrome P-450-Dependent Drug Metabolizing Enzyme Activities in Mouse and Human Tissues In Vitro / In Vitro Treatment with Metallocene Dichlorides: Determination of the Intracellular Distribution of the Metal Atoms by Use of the Electron Energy Loss Spectroscopy / Morphological Changes Induced by 2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD) in Epithelial Monolayer Culture Using Human and Rodent Fetal Tissues / V. Studies on Non-mammalian Tissues -- The Chick Embryo: A Standard Against Which to Judge In Vitro Systems / Experimental Manipulation Leading to Cardiac Malformation in Chick Embryo / Morphogenese Systems and In Vitro Techniques in Teratology / VI. Culture Techniques for "Screening" on Teratogenicity -- An Assessment of the Available In Vitro Techniques for Detecting Teratogens / On the Predictability of Developmental Toxicity -especially Prenatal Toxicity - On the Basis of Culture Experiments / VII. Some Methods Used for Culturing Embryonic Tissues -- A. Whole-Embryo-Culture: Beck; Anschiitz -- B. Limb Bud Method: Blankenburg -- C. Trowell Method: Zimmermann -- D. "Micro-Mass Culture": Zimmermann -- E. Preimplantation-Embryo Culture -- F. Teratogenicity Testing Method (Chick) -- G. CHEST I and II (Chick): Jelinek and Peterka -- Glossary -- List of Participants -- Index -- Backmatter |
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Format: | Mode of access: Internet via World Wide Web. |
ISBN: | 9783110858242 9783110637861 |
DOI: | 10.1515/9783110858242 |
Access: | restricted access |
Hierarchical level: | Monograph |
Statement of Responsibility: | Diether Neubert, Hans J. Merker, J. Klein-Friedrich, R. Kreft. |