Culture Techniques : : Applicability for Studies on Prenatal Differentiation and Toxicity. Fifth Symposium on Prenatal Development, May 1981, Berlin / / Diether Neubert, Hans J. Merker, J. Klein-Friedrich, R. Kreft.

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Bibliographic Details
Superior document:Title is part of eBook package: De Gruyter DGBA Medicine and Life Sciences - <1990
HerausgeberIn:
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Place / Publishing House:Berlin ;, Boston : : De Gruyter, , [2019]
©1981
Year of Publication:2019
Edition:Reprint 2019
Language:French
Online Access:
Physical Description:1 online resource (621 p.) :; Num. figs.
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Description
Other title:Frontmatter --
Dedication --
Preface --
Table of Contents --
Introduction /
I. Studies on Whole-Embryo Culture --
Differentiation of Embryonic Tissues in Whole-Embryo Cultures as Compared to the Development In Vivo /
The Differentiation Between Teratogenic Action on Mother, Fetal Membranes and Embryos Using the Whole-Embryo Culture Method /
Trypan Blue Teratogenesis in the Rat In Vitro /
Studies on Embryotoxic Effects of Thallium Using the Whole-Embryo Culture Technique /
Evaluation of Serum Teratogenic Activity Using Rat Embryo Cultures /
Regulation of Mouse Embryogenesis by Exogenous Growth Factors /
Preliminary Communication on the Feasibility of Culturing Whole Embryos in a Chemically Defined Medium /
In Vitro Development of the Heart Under Influence of Retinole Acid /
II. Studies on Organ Cultures --
A. Differentiation of the Skeleton (predominantly Extremities) --
Simulation of Limb Bud Skeletogenesis In Vitro /
Comparison of the Differentiation of Muscle and Connective Tissue of Mouse Limb Buds in Culture and In Vivo: A Morphological Study by Indirect Immunofluorescence /
Quantification of Collagen Types I and II in Mouse Limbs during Differentiation In Vitro and In Vivo /
Feasibility of Storing Embryonic Tissues for Subsequent Use in Organ Culture /
Limb Bud Organ Cultures from Mouse Embryos after Apparent Induction of Monooxygenases In Utero. Effects of Cyclophosphamide, Dimethylnitrosamine and Some Thalidomide Derivatives /
On the Significance of Ascorbate and of Cysteine on Differentiation of Limb Buds in Organ Culture /
Effects of Some "Indirectly" Alkylating Agents on Differentiation of Limb Buds in Organ Culture /
Comparison of Effects on Limb Development In Vivo and In Vitro Using Methyl(acetoxymethyl)nitrosamine /
Development of Limb Buds in Organ Culture: Examination of Hydroxyurea Enhancement of Bromodeoxyuridine Toxicity Using Image Analysis /
Biochemical Characterization of Mouse Hereditary Chondrodystrophies in Organ Culture /
Effect of Teratogens on Human Embryonic Skeletal Tissue In Vitro /
Aspirin Induced Polydactyly in Rats Mediated by Inhibition of Prostaglandin Synthesis /
B. Differentiation of other Organ Anlagen (kidneys, lungs, heart, prostate gland, haematopoetic system, and intestine) --
The Developing Kidney as a Model System for Normal and Impaired Organogenesis /
The Embryonic Lung as In Vitro Model for Testing Teratogenic Substances /
The Toxic Effects of Metal Dusts on Human Foetal Lungs In Vitro /
Effects of Substances Influencing Glycosaminoglycan Synthesis on Lung Development in Culture /
Effects of L-azetidine-2-carboxylic Acid and ß-D-xylosides on Lung Development In Vitro /
Interaction of Epithelium and Mesenchyme in the Induction of Foetal Rat and Mouse Prostate Glands by Androgens in Organ Culture /
In Vivo and In Vitro Assays of Trisomie Cells Isolated from the Fetal Organism or Rescued by Transfer to Non-Trisomic Hosts /
Effects of Gliadin-derived Peptides from Bread and Durum Wheat on Small Intestine Cultures from Rat Fetus and Coeliac Children /
III. Studies on Preimplantation Embryos --
Differential Adhesiveness as a Mechanism of Cell Allocation to Inner Cell.Mass and Trophectoderm in the Mouse Blastocyst /
Inefficient Capacity for Oxidative Phosphorylation of the Trophoblast as a Cause of Delayed Implantation in the Mouse /
Influence of Micromanipulation of Ova on the Postnatal Development of Mice (AKR) /
Investigations on the Mechanism of Action and on the Pharmacokinetics of Cyclophosphamide Treatment during the Preimplantation Period in the Mouse /
Benzo(a)pyrene Metabolism in Early Mouse Embryos /
IV. Studies on Cell and Tissue Cultures --
Influence of Different Antisera on Mouse Epiphyseal Chondrocytes in Monolayer Culture /
Cell Movement during Blastema Formation. Effect of Cytochalasin B on Cartilage Development In Vitro /
Cell-Substrate Adhesion of Fibroblast-like Cells Under Different In Vitro Conditions. A Scanning and Transmission Electron-Microscopic Study /
Development of Cytochrome P-450-Dependent Drug Metabolizing Enzyme Activities in Mouse and Human Tissues In Vitro /
In Vitro Treatment with Metallocene Dichlorides: Determination of the Intracellular Distribution of the Metal Atoms by Use of the Electron Energy Loss Spectroscopy /
Morphological Changes Induced by 2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD) in Epithelial Monolayer Culture Using Human and Rodent Fetal Tissues /
V. Studies on Non-mammalian Tissues --
The Chick Embryo: A Standard Against Which to Judge In Vitro Systems /
Experimental Manipulation Leading to Cardiac Malformation in Chick Embryo /
Morphogenese Systems and In Vitro Techniques in Teratology /
VI. Culture Techniques for "Screening" on Teratogenicity --
An Assessment of the Available In Vitro Techniques for Detecting Teratogens /
On the Predictability of Developmental Toxicity -especially Prenatal Toxicity - On the Basis of Culture Experiments /
VII. Some Methods Used for Culturing Embryonic Tissues --
A. Whole-Embryo-Culture: Beck; Anschiitz --
B. Limb Bud Method: Blankenburg --
C. Trowell Method: Zimmermann --
D. "Micro-Mass Culture": Zimmermann --
E. Preimplantation-Embryo Culture --
F. Teratogenicity Testing Method (Chick) --
G. CHEST I and II (Chick): Jelinek and Peterka --
Glossary --
List of Participants --
Index --
Backmatter
Format:Mode of access: Internet via World Wide Web.
ISBN:9783110858242
9783110637861
DOI:10.1515/9783110858242
Access:restricted access
Hierarchical level:Monograph
Statement of Responsibility: Diether Neubert, Hans J. Merker, J. Klein-Friedrich, R. Kreft.