Mammalian Cell Biotechnology in Protein Production /

Mammalian Cell Biotechnology in Protein Production / / ed. by Hansjörg Hauser, Roland Wagner.

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“Hauser and Wagner have presented the new possibilities of Mammalian Cell Biology in a very informative and stimulating manner.” Prof. Dr. Hans Fritz, Ludwig-Maximilians-University Munich

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Bibliographic Details
Superior document:Title is part of eBook package: De Gruyter DGBA Medicine and Life Sciences 1990 - 1999
MitwirkendeR:
Allgaier, Hermann,
Chalmers, Jeffrey J.,
Chattopadhyay, Devamita,
Dorner, Friedrich,
Engasser, Jean-Marc,
Falkner, Falko G.,
Freitag, Ruth,
Garcia-Briones, Miguel,
Goergen, Jean-Louis,
Hauser, Hansjörg,
Himmelspach, Michèle,
Jungbauer, Alois,
Kaluza, Brigitte,
Lieber, Andre,
Marc, Annie,
Onions, David,
Sandig, Volker,
Savage, Angela,
Scheper, Thomas,
Schlokat, Uwe,
Schäffner, Michaela,
Scrienc, Friedrich,
Strauss, Michael,
Tokashiki, Michiyuki,
Venkat, Raghavan,
Wagner, Roland,
Walter, Joachim,
Weidle, Ulrich Η.,
Wirth, Manfred,
Wurm, Florian Μ.,
Yokoyama, Seiichi,
HerausgeberIn:
Hauser, Hansjörg,
Wagner, Roland,
Place / Publishing House:Berlin ;, Boston : : De Gruyter, , [2011]
©1997
Year of Publication:2011
Language:English
Online Access:
Physical Description:1 online resource (491 p.)
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Table of Contents:
  • I-IV
  • Preface
  • Contents
  • Contributors List
  • 1. Genetic Manipulation of Mammalian Cells
  • 1.1 Heterologous Expression of Genes in Mammalian Cells
  • 1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection
  • 1.3 Vectors for Gene Transfer and Expression in Animal Cells
  • 1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells
  • 1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene
  • 1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells
  • 1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines
  • 2. Biological Aspects of Animal Cells
  • 2.1 Metabolic Control of Animal Cell Culture Processes
  • 2.2 Glycosylation: A Post-Translational Modification
  • 3. Cell Cultivation Technology
  • 3.1 Bioreactors Designed for Animal Cells
  • 3.2 Hydrodynamic Properties in Bioreactors
  • 3.3 Kinetics and Simulation of Animal Cell Processes
  • 3.4 On-line and Off-line Process Analysis
  • 4. Down-Stream Processing
  • 4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins
  • 4.2 Validation of Downstream Processes
  • Index
  • 492

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