Molecular Biology of Prostate Cancer / / ed. by B. Schmitz-Dräger, J. E. Altwein, Manfred Wirth, S. Kuptz.

• Superior document: Title is part of eBook package: De Gruyter DGBA Medicine and Life Sciences 1990 - 1999
• MitwirkendeR: Ackermann, R.,; Alken, P.,; Altwein, J. E.,; Bartsch, G.,; Beduschi, M. C.,; Beduschi, R.,; Bendhack, M.,; Bova, G. S.,; Brewster, S. F.,; Bruchovsky, N.,; Bussemakers, M. J. G.,; Buttyan, R.,; Cato, A. C. Β.,; Chung, L. W. K.,; Culig, Z.,; Ellis, W. J.,; Furr, B. J. A.,; Gleave, M.,; Goldenberg, S. L.,; Greschner, M.,; Griffiths, K.,; Heicappell, R.,; Hittmair, A.,; Hobisch, A.,; Isaacs, W. B.,; Kao, C.,; Klocker, H.,; Kurth, K.-H.,; Köhrmann, K.-U.,; Lange, P. H.,; Licht, Th.,; Marmé, D.,; Melchior, S. W.,; Oesterling, J. E.,; Olsson, C. A.,; Paul, R.,; Peehl, D. M.,; Peterziel, H.,; Pilarsky, Ch. P.,; Rennie, P.,; Sauter, G.,; Schalken, J. A.,; Schamhart, D. H. J.,; Schmidt, B.,; Schmitz-Dräger, Β. J.,; Schummer, Β.,; Siegsmund, M. J.,; Sikes, R. A.,; Steidler, A.,; Vessella, R. L.,; Zhau, H. E.,
• HerausgeberIn: Altwein, J. E.,; Kuptz, S.,; Schmitz-Dräger, B.,; Wirth, Manfred,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2013]; ©1998
• Year of Publication: 2013
• Edition: Reprint 2013
• Language: English
• Physical Description: 1 online resource (208 p.)

Table of Contents

• Frontmatter
• Preface
• Contents
• List of first-mentioned contributors
• Cytogenetic alterations in prostate cancer
• The regulation of prostatic growth
• Current concepts of oncogenes in prostate cancer
• Tumour suppressor genes in prostate cancer
• The use of differential display PCR for the detection of new tumor suppressor genes in prostate cancer
• Molecular alterations associated with prostate cancer development
• Dysfunction of the cell-cell adhesion complex in lethal prostate cancer
• Heparan sulfate proteoglycans and prostate cancer: a conceptual framework
• Androgen receptor mutations in prostate cancer
• Antiandrogen binding to androgen receptors and the consequences
• Expression of the MDR1 gene in prostate carcinoma
• Human prostate cancer progression models and therapeutic intervention
• Tumor angiogenesis: the VEGF signalling system is a novel target for prostate cancer therapy
• Antimetastatic approaches to therapy of prostate cancer
• Intermittent androgen suppression: rationale and clinical experience
• Resistance to drug therapy in cancer: gene therapy approaches to overcome anticancer drug resistance
• PSA RT-PCR: current status and future potential
• Special aspects of PSMA and PSA RT-PCR for the detection of disseminated prostate cells
• Molecular forms of PSA, PSA density, age-/racespecific reference ranges, and PSA velocity
• Reverse transcriptase-polymerase chain reaction assays used for molecular staging of prostate cancer patients
• Concluding remarks