Mathematical Modeling of Evolution. / Volume 1, : One-Locus and Multi-Locus Theory and Recombination / / Igor M. Rouzine.

• Superior document: Title is part of eBook package: De Gruyter DG Ebook Package English 2021
• VerfasserIn: Rouzine, Igor M.,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2020]; ©2021
• Year of Publication: 2020
• Language: English
• Series: De Gruyter Series in Mathematics and Life Sciences , 8/1
• Physical Description: 1 online resource (X, 171 p.)
• Other title: Frontmatter --; Preface --; Contents --; Chapter 1 Basic theory of one-locus evolution --; Chapter 2 Multi-locus theory of asexual populations --; Chapter 3 Multi-site evolution with recombination --; References --; De Gruyter Series in Mathematics and Life Sciences
• Format: Mode of access: Internet via World Wide Web.
• ISBN: 9783110615456; 9783110750720; 9783110750706; 9783110659061; 9783110704716; 9783110704518; 9783110704846; 9783110704662
• ISSN: 2195-5530
• DOI: 10.1515/9783110615456
• Access: restricted access
• Hierarchical level: Monograph
• Statement of Responsibility: Igor M. Rouzine.

The book will benefit a reader with a background in physical sciences and applied mathematics interested in the mathematical models of genetic evolution. In the first chapter, we analyze several thought experiments based on a basic model of stochastic evolution of a single genomic site in the presence of the factors of random mutation, directional natural selection, and random genetic drift. In the second chapter, we present a more advanced theory for a large number of linked loci. In the third chapter, we include the effect of genetic recombination into account and find out the advantage of sexual reproduction for adaptation. These models are useful for the evolution of a broad range of asexual and sexual populations, including virus evolution in a host and a host population.