Mass Spectrometry in Biopharmaceutical Analysis / / Igor A. Kaltashov, Guanbo Wang, Shunhai Wang.

• Superior document: Title is part of eBook package: De Gruyter DG Plus DeG Package 2022 Part 1
• VerfasserIn: Kaltashov, Igor A.,; Wang, Guanbo,; Wang, Shunhai,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2021]; ©2022
• Year of Publication: 2021
• Language: English
• Physical Description: 1 online resource (X, 270 p.)
• Other title: Frontmatter --; Preface --; Contents --; Chapter 1 Analytical chemistry in biopharma --; Chapter 2 A brief overview of biological mass spectrometry: concepts and definitions --; Chapter 3 Characterization of covalent structure of protein therapeutics --; Chapter 4 Characterization of higher order structure and protein interactions --; Chapter 5 Biosimilars and comparability studies --; Chapter 6 Characterization of impurities in biopharmaceutical products --; Chapter 7 Quantitation of protein therapeutics in biological samples --; Chapter 8 Non-protein biopharmaceuticals and related macromolecular drugs --; Chapter 9 What is next? --; Index
• Format: Mode of access: Internet via World Wide Web.
• ISBN: 9783110546187; 9783110766820; 9783110616859; 9783110754001; 9783110753776; 9783110754162; 9783110753936
• DOI: 10.1515/9783110546187
• Access: restricted access
• Hierarchical level: Monograph
• Statement of Responsibility: Igor A. Kaltashov, Guanbo Wang, Shunhai Wang.

Biopharmaceuticals are a unique class of compounds due to their extreme structural complexity. The current text puts together a variety of the state-of-the art approaches that use mass spectrometry to evaluate various aspects of biopharmaceutical products ranging from monitoring stress-related structural changes to their quantitation in pharmacokinetic studies.