Metal-Carbon Bonds in Enzymes and Cofactors / / ed. by Helmut Sigel, Astrid Sigel, Roland K.O. Sigel.

• Superior document: Title is part of eBook package: De Gruyter DGBA Backlist Complete English Language 2000-2014 PART1
• MitwirkendeR: Brunold, Thomas C.,; Ermler, Ulrich,; Fontecilla-Camps, Juan C.,; Hille, Russ,; Jaun, Bernhard,; Karlin, Kenneth D.,; Kroneck, Peter M. H.,; Kräutler, Bernhard,; Lindahl, Paul A.,; Liptak, Matthew D.,; Lucas, Heather R.,; Matthews, Rowena G.,; Peters, John W.,; Rivera, Mario,; Rodríguez, Juan C.,; Shima, Seigo,; Sigel, Astrid,; Sigel, Helmut,; Sigel, Roland K. O.,; Sosa-Torres, Martha E.,; Thauer, Rudolf K.,; Van Heuvelen, Katherine M.,
• HerausgeberIn: Sigel, Astrid,; Sigel, Helmut,; Sigel, Roland K.O.,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2015]; ©2009
• Year of Publication: 2015
• Language: English
• Series: Metal Ions in Life Sciences , 6
• Physical Description: 1 online resource (510 p.)

The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic.

Table of Contents

Frontmatter -- Historical Development and Perspectives of the Series -- Preface to Volume 6: Metal-Carbon Bonds in Enzymes and Cofactors -- Contents -- Contributors to Volume 6 -- Titles of Volumes 1–44 in the Metal Ions in Biological Systems Series -- 1 Organometallic Chemistry of B12 Coenzymes -- 2 Cobalamin- and Corrinoid-Dependent Enzymes -- 3 Nickel-Alkyl Bond Formation in the Active Site of Methyl-Coenzyme M Reductase -- 4 Nickel-Carbon Bonds in Acetyl-Coenzyme A Synthases/Carbon Monoxide Dehydrogenases -- 5 Structure and Function of [NiFe]-Hydrogenases -- 6 Carbon Monoxide and Cyanide Ligands in the Active Site of [FeFe]-Hydrogenases -- 7 Carbon Monoxide as Intrinsic Ligand to Iron in the Active Site of [Fe]-Hydrogenase -- 8 The Dual Role of Heme as Cofactor and Substrate in the Biosynthesis of Carbon Monoxide -- 9 Copper-Carbon Bonds in Mechanistic and Structural Probing of Proteins as well as in Situations where Copper is a Catalytic or Receptor Site -- 10 Interaction of Cyanide with Enzymes Containing Vanadium, Manganese, Non-Heme Iron, and Zinc -- 11 The Reaction Mechanism of the Molybdenum Hydroxylase Xanthine Oxidoreductase: Evidence Against the Formation of Intermediates Having Metal-Carbon Bonds -- 12 Computational Studies of Bioorganometallic Enzymes and Cofactors -- Subject Index -- Author Index of Contributors to MIBS and MILS