Stem Cell-Dependent Therapies : : Mesenchymal Stem Cells in Chronic Inflammatory Disorders /

Stem Cell-Dependent Therapies : : Mesenchymal Stem Cells in Chronic Inflammatory Disorders / / ed. by Gerhard Gross, Thomas Häupl.

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Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activitie...

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Superior document:Title is part of eBook package: De Gruyter DGBA Backlist Complete English Language 2000-2014 PART1
MitwirkendeR:
Abdi, Reza,
Almeida, Danilo Candido de,
Almeida-Porada, Graça,
Bassi, Ênio Jose,
Bergfeld, Scott A.,
Bocelli-Tyndall, Chiara,
Bühler, Léo H.,
Chang, Astra I.,
Charbord, Pierre,
Cordano, Christian,
DeClerck, Yves A.,
Dennis, James E.,
Durand, Charles,
Gonelle-Gispert, Carmen,
Gross, Gerhard,
Hoffmann, Andrea,
Hollander, Anthony P.,
Häupl, Thomas,
Kastrup, Jens,
Kerlero de Rosbo, Nicole,
Kurtz, Andreas,
Laggies, Sandra,
Lord, James D.,
Magee, Ciara N.,
Mounayar, Marwan,
Nolta, Jan A.,
Oh, Su-Jun,
Olsen Saraiva Câmara, Niels,
Pileggi, Antonello,
Porada, Christopher D.,
Qayyum, Abbas Ali,
Ricordi, Camillo,
Ringdén, Olle,
Rojas, Mauricio,
Sadeghi, Behnam,
Seiffart, Virginia,
Taemi Origassa, Clarice Silvia,
Tan, Jianming,
Tyndall, Alan,
Uccelli, Antonio,
Weiss, Daniel J.,
Wraith, David C.,
Wu, Jian,
Xu, Xiumin,
Zhang, Shang,
TeilnehmendeR:
Almeida-Porada, Graca.
Bühler, Leo.
Camara, Niels Olsen Saraiva.
Charbord, Pierre .
DeClerck, Yves A.
Dennis, James E.
Gonelle-Gispert, Carmen.
Kastrup, Jens.
Kurtz, Andreas .
Pileggi, Antonello.
Ringdén, Olle.
Rojas, Mauricio .
Tyndall, Alan.
Uccelli, Antonio.
Weiss, Daniel.
Wraith, David.
Wu, Jian.
HerausgeberIn:
Gross, Gerhard,
Häupl, Thomas,
Place / Publishing House:Berlin ;, Boston : : De Gruyter, , [2013]
©2013
Year of Publication:2013
Language:English
Online Access:
Physical Description:1 online resource (408 p.)
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019 |a (OCoLC)1013939086 
019 |a (OCoLC)1029820630 
019 |a (OCoLC)1032683215 
019 |a (OCoLC)1037982165 
019 |a (OCoLC)1041976955 
019 |a (OCoLC)1046613280 
019 |a (OCoLC)1047011520 
019 |a (OCoLC)1048336065 
020 |a 9783110298307 
024 7 |a 10.1515/9783110298307  |2 doi 
035 |a (DE-B1597)178984 
035 |a (OCoLC)979750441 
040 |a DE-B1597  |b eng  |c DE-B1597  |e rda 
041 0 |a eng 
044 |a gw  |c DE 
050 0 0 |a RB131  |b .S73 2013 
050 4 |a QH588.S83  |b S84 2013 
072 7 |a MED009000  |2 bisacsh 
082 0 4 |a 616/.0473  |2 23 
245 0 0 |a Stem Cell-Dependent Therapies :  |b Mesenchymal Stem Cells in Chronic Inflammatory Disorders /  |c ed. by Gerhard Gross, Thomas Häupl. 
264 1 |a Berlin ;  |a Boston :   |b De Gruyter,   |c [2013] 
264 4 |c ©2013 
300 |a 1 online resource (408 p.) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 0 |t Frontmatter --   |t Preface --   |t Contributing authors --   |t Table of Contents --   |t 1 Mesenchymal stem cells in the context of stem cell biology --   |t 2 Are mesenchymal stem cells immune privileged? --   |t 3 Mesenchymal stem cell therapies for autoimmune diseases --   |t 4 Mesenchymal stem cells in osteoarthritis and rheumatic disease --   |t 5 Mesenchymal stem cells in enthesis formation and repair --   |t 6 Mesenchymal stem cells for clinical/therapeutic interventions of graft-versus-host disease --   |t 7 Mesenchymal stem cells for graft-versus-host disease in experimental animal models --   |t 8 Mesenchymal stem cells and organ transplantation : initial clinical results --   |t 9 Stem cell therapy in patients with ischemic heart disease --   |t 10 Mesenchymal stem cells as a strategy for the treatment of multiple sclerosis and other diseases of the central nervous system --   |t 11 Mesenchymal stem cells for the treatment of inflammatory bowel disease --   |t 12 Mesenchymal stem cells in chronic lung diseases: COPD and lung fibrosis --   |t 13 Mesenchymal stem cells as therapeutics for liver repair and regeneration --   |t 14 Mesenchymal stem cells attenuate renal fibrosis --   |t 15 Immunomodulation by mesenchymal stem cells – a potential therapeutic strategy for type 1 diabetes --   |t 16 Fibrogenic potential of human multipotent mesenchymal stem cells in inflammatory environments --   |t 17 Mesenchymal stem cells and the tumor microenvironment --   |t 18 Mesenchymal stem cells as a carrier for tumor-targeting therapeutics --   |t 19 Systems biology approach to stem cells, tissues and inflammation --   |t Index 
506 0 |a restricted access  |u http://purl.org/coar/access_right/c_16ec  |f online access with authorization  |2 star 
520 |a Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation. 
538 |a Mode of access: Internet via World Wide Web. 
546 |a In English. 
588 0 |a Description based on online resource; title from PDF title page (publisher's Web site, viewed 30. Aug 2021) 
650 0 |a Chronic Disease  |x therapy. 
650 0 |a Inflammation  |x Immunological aspects. 
650 0 |a Inflammation  |x Treatment. 
650 0 |a Mesenchymal Stem Cell Transplantation. 
650 4 |a Autoimmunkrankheit. 
650 4 |a Chronische Entzündung. 
650 4 |a Regenerative Medizin. 
650 4 |a Stammzellen. 
650 7 |a MEDICAL / Biotechnology.  |2 bisacsh 
653 |a Autoimmune Disorders. 
653 |a Immunomodulation. 
653 |a Inflammation. 
653 |a Regenerative Medicine. 
653 |a Stem Cells. 
700 1 |a Abdi, Reza,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Almeida, Danilo Candido de,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Almeida-Porada, Graca. 
700 1 |a Almeida-Porada, Graça,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Bassi, Ênio Jose,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Bergfeld, Scott A.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Bocelli-Tyndall, Chiara,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Bühler, Leo. 
700 1 |a Bühler, Léo H.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Camara, Niels Olsen Saraiva. 
700 1 |a Chang, Astra I.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Charbord, Pierre . 
700 1 |a Charbord, Pierre,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Cordano, Christian,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a DeClerck, Yves A. 
700 1 |a DeClerck, Yves A.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Dennis, James E. 
700 1 |a Dennis, James E.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Durand, Charles,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Gonelle-Gispert, Carmen,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Gonelle-Gispert, Carmen. 
700 1 |a Gross, Gerhard,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Gross, Gerhard,   |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Hoffmann, Andrea,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Hollander, Anthony P.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Häupl, Thomas,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Häupl, Thomas,   |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Kastrup, Jens,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Kastrup, Jens. 
700 1 |a Kerlero de Rosbo, Nicole,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Kurtz, Andreas . 
700 1 |a Kurtz, Andreas,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Laggies, Sandra,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Lord, James D.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Magee, Ciara N.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Mounayar, Marwan,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Nolta, Jan A.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Oh, Su-Jun,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Olsen Saraiva Câmara, Niels,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Pileggi, Antonello,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Pileggi, Antonello. 
700 1 |a Porada, Christopher D.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Qayyum, Abbas Ali,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Ricordi, Camillo,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Ringdén, Olle,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Ringdén, Olle. 
700 1 |a Rojas, Mauricio . 
700 1 |a Rojas, Mauricio,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Sadeghi, Behnam,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Seiffart, Virginia,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Taemi Origassa, Clarice Silvia,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Tan, Jianming,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Tyndall, Alan,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Tyndall, Alan. 
700 1 |a Uccelli, Antonio,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Uccelli, Antonio. 
700 1 |a Weiss, Daniel J.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Weiss, Daniel. 
700 1 |a Wraith, David C.,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Wraith, David. 
700 1 |a Wu, Jian,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Wu, Jian. 
700 1 |a Xu, Xiumin,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
700 1 |a Zhang, Shang,   |e contributor.  |4 ctb  |4 https://id.loc.gov/vocabulary/relators/ctb 
773 0 8 |i Title is part of eBook package:  |d De Gruyter  |t DGBA Backlist Complete English Language 2000-2014 PART1  |z 9783110238570 
773 0 8 |i Title is part of eBook package:  |d De Gruyter  |t DGBA Backlist Medicine and Life Sciences 2000-2014 (EN)  |z 9783110238495 
773 0 8 |i Title is part of eBook package:  |d De Gruyter  |t DGBA Medicine and Life Sciences 2000 - 2014  |z 9783110637915  |o ZDB-23-GML 
773 0 8 |i Title is part of eBook package:  |d De Gruyter  |t E-BOOK GESAMTPAKET / COMPLETE PACKAGE 2013  |z 9783110317350  |o ZDB-23-DGG 
773 0 8 |i Title is part of eBook package:  |d De Gruyter  |t E-BOOK PACKAGE CHEMISTRY, MATERIALS SC., BIOL., GEOSC. 2013  |z 9783110317176 
773 0 8 |i Title is part of eBook package:  |d De Gruyter  |t E-BOOK PAKET CHEMIE, MATERIALWISS., BIOLOGIE, GEOWISS. 2013  |z 9783110317169  |o ZDB-23-DCM 
776 0 |c print  |z 9783110298260 
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912 |a 978-3-11-023857-0 DGBA Backlist Complete English Language 2000-2014 PART1  |c 2000  |d 2014 
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