The CliniBook : : Clinical gene transfer state of the art / / Odile Cohen-Haguenauer.
This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory is...
Saved in:
Superior document: | Title is part of eBook package: De Gruyter EDP Sciences Backlist eBook Package 2000-2013 |
---|---|
VerfasserIn: | |
MitwirkendeR: | |
Place / Publishing House: | Les Ulis : : EDP Sciences, , [2012] ©2012 |
Year of Publication: | 2012 |
Language: | English |
Online Access: | |
Physical Description: | 1 online resource (589 p.) |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
9782842542375 |
---|---|
ctrlnum |
(DE-B1597)634993 (OCoLC)834607434 |
collection |
bib_alma |
record_format |
marc |
spelling |
Cohen-Haguenauer, Odile, author. aut http://id.loc.gov/vocabulary/relators/aut The CliniBook : Clinical gene transfer state of the art / Odile Cohen-Haguenauer. Les Ulis : EDP Sciences, [2012] ©2012 1 online resource (589 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Frontmatter -- CliniGene Partners and Boards -- ACKNOWLEDGMENTS -- List of authors -- Contents -- INTRODUCTION -- In-1 Foreword -- In-2 Main achievements and prospects downstream of the CliniGene-NoE -- PART I: TECHNOLOGIES AND PRE-CLINICAL STUDIES -- TECHNOLOGIES - Highlights on AAV mediated gene transfer -- A1-1 Highlights on AAV mediated gene transfer: introduction -- A1-2 Preclinical studies of AAV gene therapy for inherited retinal dystrophies -- A1-3 AAV-mediated gene therapy for MPS VI -- A1-4 Microdystrophin and myostatin gene therapy for Duchenne muscular dystrophy using adeno-associated virus vectors -- A1-5 AAV gene therapy for cardiovascular disorders -- A1-6 AAV gene therapy for diabetes mellitus -- A1-7 Approaches to large scale production of AAV-vectors -- A1-8 Reference materials for the characterization of adeno-associated viral vectors -- TECHNOLOGIES - Retrovirus mediated gene transfer state-of-the-art -- A2-1 Highlights on retrovirus mediated gene transfer -- A2-2 Retroviral vector development: reducing genotoxicity of integrated DNA and creating virus-like particles for transient cell modification -- A2-3 Replication-competent y-retroviral vectors for tumor therapy -- A2-4 Modular retroviral producer cell lines -- TECHNOLOGIES - Highlights on lentivirus mediated gene transfer -- A3-1 Introduction -- A3-2 MicroRNAs detargeting technology in the context of CNS applications -- A3-3 Development of SIVsmmPBj vectors for gene transfer into myeloid cells -- A3-4 Insulated retrovirus vectors using novel synthetic genetic insulator elements to circumvent enhancer-mediated genotoxicity -- A3-5 Facing the challenges of downstream processing of lentiviral vectors -- A3-6 Restrictions and requirements for stable lentiviral vector production in HEK293 cells -- A3-7 Novel lentiviral vector pseudotypes for stable gene transfer into resting hematopoietic cells -- TECHNOLOGIES - Highlights on gene-modified cell therapy -- A4-1 Cell therapy Introduction -- A4-2 Ex-vivo expansion of human mesenchymal stem cells -- A4-3 Closed bag cultivation systems for the production of gene modified dendritic cells and MSC for clinical use -- A4-4 Genetically modified NK cells for cancer treatment: facts and visions -- A4-5 Regulatory T lymphocyte depletion for cancer immunotherapies -- A4-6 Gene therapy of Fanconi’s anaemia aplastic syndrome -- TECHNOLOGIES - Adenovirus mediated gene transfer: current developments -- A5-1 Overview on adenovirus vectors -- A5-2 Tumour barriers influencing adenovirus vector delivery and therapeutic efficacy -- A5-3 Tumor imaging with adenoviral vectors -- A5-4 Treatment of brain tumors with adenoviruses: preclinical development -- A5-5 Production and purification of Ad vectors: current status and future needs for adenovirus vector production -- TECHNOLOGIES - Non-viral based gene transfer: a new era -- A6-1 Non viral plasmid delivery and imaging of transgene expression A6-1 Non viral plasmid delivery and imaging of transgene expression -- A6-2 Overview of novel plasmid vectors and preclinical applications -- A6-3 Filling a gap: S/MAR-based replicating minicircles -- A6-4 Manufacturing and QC of plasmid based vectors -- A6-5 Sleeping Beauty transposon based gene therapy -- A6-6 Development of minicircle vectors -- A6-7 Exon skipping therapy for DMD using antisense oligomer technology -- TECHNOLOGIES - Highlights on emerging technologies, iPS induction and genetic stability -- A7-1 Induction of pluripotency from adult somatic cells: a review -- A7-2 Genetic modification of adult stem cells and induced pluripotent stem cells with emerging transposon technologies -- A7-3 Targeted genome engineering approaches based on rare-cutting endonucleases: a tentative summary -- A7-4 Targeted genome modifications with designer nucleases -- PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - Preclinical assessment tools -- B1-1 Preclinical assessment tools: imaging gene transfer to the brain -- B1-2 Persistent luminescence nanoparticles for in vivo imaging: characteristics and targeting -- B1-3 Ex-vivo evaluation of gene-transfer vectors: efficacy, tropism and safety -- PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - General biosafety: immune responses, immunotoxicity and genotoxicity -- B2-1 Assessing and taming unwanted immune responses induced by AAV gene transfer: current status, ongoing questions and future prospects -- B2-2 Predicting immune responses to viral vectors and transgenes in gene therapy and vaccination: the coming of systems biology -- B2-3 Biosafety analysis in preclinical and clinical studies -- PART II Clinical trials and regulatory issues -- CLINICAL TRIALS -- C1-1 A clinical trial of AAV-mediated gene therapy for Leber congenital amaurosis 2 -- C1-2 Gene therapy for X-linked adrenoleukodystrophy based on lentiviral correction of hematopoietic stem cells -- C1-3 Immune reconstitution after gene therapy for adenosine deaminase severe combined immunodeficiency (ADA-SCID) -- C1-4 Gene therapy in Alzheimer disease patients -- C1-5 Cardiovascular gene therapy trials -- C1-6 AAV-mediated gene therapy for haemophilia B -- C1-7 ProSavin®: a lentiviral vector approach for the treatment of Parkinson’s disease -- ETHICAL AND REGULATORY ISSUES -- C2-1 Ethics in translation from research to therapy -- C2-2 Centralised regulation of gene therapy in Europe -- C2-3 The necessity for data sharing towards advancement of clinical translation Building up sample IMPD* and substantiating master files -- INTEGRATION AND DISSEMINATION -- C3-1 European Union support to gene transfer and gene therapy -- C3-2 Database of clinical trials -- C3-3 CliniGene and ESGCT shared vision for gene therapy in Europe: past, present and future prospects -- AUTHOR INDEX restricted access http://purl.org/coar/access_right/c_16ec online access with authorization star This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation. Mode of access: Internet via World Wide Web. In English. Description based on online resource; title from PDF title page (publisher's Web site, viewed 01. Dez 2022) Genetic transformation. MEDICAL / Laboratory Medicine. bisacsh Aiuti, Alessandro, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Ali, Robin R., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Alici, Evren, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Almqvist, Per, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Annunziata, Patrizia, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Anton, Martina, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Artus, Alexandre, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Athanasopoulos, Takis, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Aubourg, Patrick, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Auregan, Gwennaelle, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Auricchio, Alberto, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bandeira, Vanessa, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bartholomae, Cynthia C., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Baum, Christopher, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bayart, Émilie, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bednarski, Christien, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bellier, Bertrand, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Biasco, Luca, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bigey, Pascal, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Blouin, Véronique, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bode, Juergen, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bonvento, Gilles, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bosch, Fatima, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bougnères, Pierre, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Brigida, Immacolata, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Broll, Sandra, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Buchholz, Christian J., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bureau, Michel-Francis, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Bárcia, Rita N., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Callejas, David, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Carina Silva, Ana, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Carrondo, Manuel J.T., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cartier, Nathalie, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cathomen, Toni, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cavazzana-Calvo, Marina, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Chuah, Marinee K.L., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cichutek, Klaus, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cohen-Haguenauer, Odile, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Colin, Angélique, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cordova, Gonzalo, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Coroadinha, Ana Sofia, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cosset, François-Loïc, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cotugno, Gabriella, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cruz, Helder J.S, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Cruz, Pedro E., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Darmon, Christophe, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Davidoff, Andrew M., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Dickson, George, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Dittmar, Kurt E.J., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Draghia-Akli, Ruxandra, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Dufour, Noëlle, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Duros, Caroline, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Déglon, Nicole, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Dürner, Lydia, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Eriksdotter-Jönhagen, Maria, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Escartin, Carole, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Escriou, Virginie, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Eyjolfsdottir, Helga, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Faideau, Mathilde, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Fischer, Alain, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Foster, Helen, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Foster, Keith, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Gahrton, Gösta, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Galla, Melanie, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Galy, Anne, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Gama-Norton, Leonor, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Garritsen, Henk S.P., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Georgiadis, Anastasios, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Giacca, Mauro, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Gilljam, Mari, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Gänsbacher, Bernd, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Hacein-Bey-Abina, Salima, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Hantraye, Philippe, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Haskins, Mark, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Hassig, Raymonde, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Hauser, Hansjörg, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Heinz, Niels, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Händel, Eva-Maria, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Ivics, Zoltán, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Izsvák, Zsuzsanna, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Jacobs, Andreas H., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Jarmin, Susan, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Jimenez, Veronica, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Kalle, Christof von, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Kang, Jagjeet, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Kent, Alastair, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Khalaileh, Abed, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Kichler, Antoine, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb King, Nancy M.P., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Klatzmann, David, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Kochanek, Stefan, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Kolodkin-Gal, Dror, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Koo, Taeyoung, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Kunicher, Nikolai, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Lachmann, Kristina, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Laufs, Stephanie, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Lemaire, Stéphanie, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Lemoine, François, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Lind, Göran, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Lindenmaier, Werner, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Linderoth, Bengt, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Lock, Martin, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Lucas, Tanja, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Luzzatto, Lucio, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Macke, Lars, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Maetzig, Tobias, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Maldiney, Thomas, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Malerba, Alberto, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Mann, Christopher, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Marie, Corinne, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Marques Alves, Paula, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Merten, Otto-Wilhelm, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Meyring, Wilhelm, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Mignet, Nathalie, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Mingozzi, Federico, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Mitrophanous, Kyriacos, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Modlich, Ute, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Monfared, Parisa, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Montini, Eugenio, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Moullier, Philippe, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Naldini, Luigi, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Nathwani, Amit C., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Nienhuis, Arthur W., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Palfi, Stéphane, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Panet, Amos, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Peixoto, Cristina, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Pohl, Susanne, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Popplewell, Linda, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Pâques, Frédéric, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Raj, Deepak, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Ralph, R. Scott, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Reiss, Ulrike, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Richard, Cyrille, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Rischmüller, Anja, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Rodrigues, Ana F., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Rosenzwajg, Michelle, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Santos, Jorge M., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Schambach, Axel, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Schaser, Thomas, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Scherman, Daniel, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Schleef, Martin, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Schmeer, Marco, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Schmidt, Manfred, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Schweizer, Matthias, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Schäfers, Sonja, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Seiger, Åke, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Simão, Daniel, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Six, Adrien, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Smith, Alexander J, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Smith, Alexander J., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Smith, Julianne, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Snyder, Richard O., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Sofia Coroadinha, Ana, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Sousa, Marcos F.Q., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Suerth, Julia D., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Sundström, Erik, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Tayeb, Shay, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Thomas, Michael, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Thomas-Vaslin, Véronique, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Tuddenham, Edward G.D., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb VandenDriessche, Thierry, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Verhoeyen, Els, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Verma, Inder M., contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Viel, Thomas, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Waerzeggers, Yannic, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Wahlberg, Lars, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Winkeler, Alexandra, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Wirth, Dagmar, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Ylä-Herttuala, Seppo, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Zacchigna, Serena, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Zamir, Gidi, contributor. ctb https://id.loc.gov/vocabulary/relators/ctb Title is part of eBook package: De Gruyter EDP Sciences Backlist eBook Package 2000-2013 9783111024110 https://doi.org/10.1051/978-2-84254-237-5 https://www.degruyter.com/isbn/9782842542375 Cover https://www.degruyter.com/document/cover/isbn/9782842542375/original |
language |
English |
format |
eBook |
author |
Cohen-Haguenauer, Odile, Cohen-Haguenauer, Odile, |
spellingShingle |
Cohen-Haguenauer, Odile, Cohen-Haguenauer, Odile, The CliniBook : Clinical gene transfer state of the art / Frontmatter -- CliniGene Partners and Boards -- ACKNOWLEDGMENTS -- List of authors -- Contents -- INTRODUCTION -- In-1 Foreword -- In-2 Main achievements and prospects downstream of the CliniGene-NoE -- PART I: TECHNOLOGIES AND PRE-CLINICAL STUDIES -- TECHNOLOGIES - Highlights on AAV mediated gene transfer -- A1-1 Highlights on AAV mediated gene transfer: introduction -- A1-2 Preclinical studies of AAV gene therapy for inherited retinal dystrophies -- A1-3 AAV-mediated gene therapy for MPS VI -- A1-4 Microdystrophin and myostatin gene therapy for Duchenne muscular dystrophy using adeno-associated virus vectors -- A1-5 AAV gene therapy for cardiovascular disorders -- A1-6 AAV gene therapy for diabetes mellitus -- A1-7 Approaches to large scale production of AAV-vectors -- A1-8 Reference materials for the characterization of adeno-associated viral vectors -- TECHNOLOGIES - Retrovirus mediated gene transfer state-of-the-art -- A2-1 Highlights on retrovirus mediated gene transfer -- A2-2 Retroviral vector development: reducing genotoxicity of integrated DNA and creating virus-like particles for transient cell modification -- A2-3 Replication-competent y-retroviral vectors for tumor therapy -- A2-4 Modular retroviral producer cell lines -- TECHNOLOGIES - Highlights on lentivirus mediated gene transfer -- A3-1 Introduction -- A3-2 MicroRNAs detargeting technology in the context of CNS applications -- A3-3 Development of SIVsmmPBj vectors for gene transfer into myeloid cells -- A3-4 Insulated retrovirus vectors using novel synthetic genetic insulator elements to circumvent enhancer-mediated genotoxicity -- A3-5 Facing the challenges of downstream processing of lentiviral vectors -- A3-6 Restrictions and requirements for stable lentiviral vector production in HEK293 cells -- A3-7 Novel lentiviral vector pseudotypes for stable gene transfer into resting hematopoietic cells -- TECHNOLOGIES - Highlights on gene-modified cell therapy -- A4-1 Cell therapy Introduction -- A4-2 Ex-vivo expansion of human mesenchymal stem cells -- A4-3 Closed bag cultivation systems for the production of gene modified dendritic cells and MSC for clinical use -- A4-4 Genetically modified NK cells for cancer treatment: facts and visions -- A4-5 Regulatory T lymphocyte depletion for cancer immunotherapies -- A4-6 Gene therapy of Fanconi’s anaemia aplastic syndrome -- TECHNOLOGIES - Adenovirus mediated gene transfer: current developments -- A5-1 Overview on adenovirus vectors -- A5-2 Tumour barriers influencing adenovirus vector delivery and therapeutic efficacy -- A5-3 Tumor imaging with adenoviral vectors -- A5-4 Treatment of brain tumors with adenoviruses: preclinical development -- A5-5 Production and purification of Ad vectors: current status and future needs for adenovirus vector production -- TECHNOLOGIES - Non-viral based gene transfer: a new era -- A6-1 Non viral plasmid delivery and imaging of transgene expression A6-1 Non viral plasmid delivery and imaging of transgene expression -- A6-2 Overview of novel plasmid vectors and preclinical applications -- A6-3 Filling a gap: S/MAR-based replicating minicircles -- A6-4 Manufacturing and QC of plasmid based vectors -- A6-5 Sleeping Beauty transposon based gene therapy -- A6-6 Development of minicircle vectors -- A6-7 Exon skipping therapy for DMD using antisense oligomer technology -- TECHNOLOGIES - Highlights on emerging technologies, iPS induction and genetic stability -- A7-1 Induction of pluripotency from adult somatic cells: a review -- A7-2 Genetic modification of adult stem cells and induced pluripotent stem cells with emerging transposon technologies -- A7-3 Targeted genome engineering approaches based on rare-cutting endonucleases: a tentative summary -- A7-4 Targeted genome modifications with designer nucleases -- PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - Preclinical assessment tools -- B1-1 Preclinical assessment tools: imaging gene transfer to the brain -- B1-2 Persistent luminescence nanoparticles for in vivo imaging: characteristics and targeting -- B1-3 Ex-vivo evaluation of gene-transfer vectors: efficacy, tropism and safety -- PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - General biosafety: immune responses, immunotoxicity and genotoxicity -- B2-1 Assessing and taming unwanted immune responses induced by AAV gene transfer: current status, ongoing questions and future prospects -- B2-2 Predicting immune responses to viral vectors and transgenes in gene therapy and vaccination: the coming of systems biology -- B2-3 Biosafety analysis in preclinical and clinical studies -- PART II Clinical trials and regulatory issues -- CLINICAL TRIALS -- C1-1 A clinical trial of AAV-mediated gene therapy for Leber congenital amaurosis 2 -- C1-2 Gene therapy for X-linked adrenoleukodystrophy based on lentiviral correction of hematopoietic stem cells -- C1-3 Immune reconstitution after gene therapy for adenosine deaminase severe combined immunodeficiency (ADA-SCID) -- C1-4 Gene therapy in Alzheimer disease patients -- C1-5 Cardiovascular gene therapy trials -- C1-6 AAV-mediated gene therapy for haemophilia B -- C1-7 ProSavin®: a lentiviral vector approach for the treatment of Parkinson’s disease -- ETHICAL AND REGULATORY ISSUES -- C2-1 Ethics in translation from research to therapy -- C2-2 Centralised regulation of gene therapy in Europe -- C2-3 The necessity for data sharing towards advancement of clinical translation Building up sample IMPD* and substantiating master files -- INTEGRATION AND DISSEMINATION -- C3-1 European Union support to gene transfer and gene therapy -- C3-2 Database of clinical trials -- C3-3 CliniGene and ESGCT shared vision for gene therapy in Europe: past, present and future prospects -- AUTHOR INDEX |
author_facet |
Cohen-Haguenauer, Odile, Cohen-Haguenauer, Odile, Aiuti, Alessandro, Aiuti, Alessandro, Ali, Robin R., Ali, Robin R., Alici, Evren, Alici, Evren, Almqvist, Per, Almqvist, Per, Annunziata, Patrizia, Annunziata, Patrizia, Anton, Martina, Anton, Martina, Artus, Alexandre, Artus, Alexandre, Athanasopoulos, Takis, Athanasopoulos, Takis, Aubourg, Patrick, Aubourg, Patrick, Auregan, Gwennaelle, Auregan, Gwennaelle, Auricchio, Alberto, Auricchio, Alberto, Bandeira, Vanessa, Bandeira, Vanessa, Bartholomae, Cynthia C., Bartholomae, Cynthia C., Baum, Christopher, Baum, Christopher, Bayart, Émilie, Bayart, Émilie, Bednarski, Christien, Bednarski, Christien, Bellier, Bertrand, Bellier, Bertrand, Biasco, Luca, Biasco, Luca, Bigey, Pascal, Bigey, Pascal, Blouin, Véronique, Blouin, Véronique, Bode, Juergen, Bode, Juergen, Bonvento, Gilles, Bonvento, Gilles, Bosch, Fatima, Bosch, Fatima, Bougnères, Pierre, Bougnères, Pierre, Brigida, Immacolata, Brigida, Immacolata, Broll, Sandra, Broll, Sandra, Buchholz, Christian J., Buchholz, Christian J., Bureau, Michel-Francis, Bureau, Michel-Francis, Bárcia, Rita N., Bárcia, Rita N., Callejas, David, Callejas, David, Carina Silva, Ana, Carina Silva, Ana, Carrondo, Manuel J.T., Carrondo, Manuel J.T., Cartier, Nathalie, Cartier, Nathalie, Cathomen, Toni, Cathomen, Toni, Cavazzana-Calvo, Marina, Cavazzana-Calvo, Marina, Chuah, Marinee K.L., Chuah, Marinee K.L., Cichutek, Klaus, Cichutek, Klaus, Cohen-Haguenauer, Odile, Cohen-Haguenauer, Odile, Colin, Angélique, Colin, Angélique, Cordova, Gonzalo, Cordova, Gonzalo, Coroadinha, Ana Sofia, Coroadinha, Ana Sofia, Cosset, François-Loïc, Cosset, François-Loïc, Cotugno, Gabriella, Cotugno, Gabriella, Cruz, Helder J.S, Cruz, Helder J.S, Cruz, Pedro E., Cruz, Pedro E., Darmon, Christophe, Darmon, Christophe, Davidoff, Andrew M., Davidoff, Andrew M., Dickson, George, Dickson, George, Dittmar, Kurt E.J., Dittmar, Kurt E.J., Draghia-Akli, Ruxandra, Draghia-Akli, Ruxandra, Dufour, Noëlle, Dufour, Noëlle, Duros, Caroline, Duros, Caroline, Déglon, Nicole, Déglon, Nicole, Dürner, Lydia, Dürner, Lydia, Eriksdotter-Jönhagen, Maria, Eriksdotter-Jönhagen, Maria, Escartin, Carole, Escartin, Carole, Escriou, Virginie, Escriou, Virginie, Eyjolfsdottir, Helga, Eyjolfsdottir, Helga, Faideau, Mathilde, Faideau, Mathilde, Fischer, Alain, Fischer, Alain, Foster, Helen, Foster, Helen, Foster, Keith, Foster, Keith, Gahrton, Gösta, Gahrton, Gösta, Galla, Melanie, Galla, Melanie, Galy, Anne, Galy, Anne, Gama-Norton, Leonor, Gama-Norton, Leonor, Garritsen, Henk S.P., Garritsen, Henk S.P., Georgiadis, Anastasios, Georgiadis, Anastasios, Giacca, Mauro, Giacca, Mauro, Gilljam, Mari, Gilljam, Mari, Gänsbacher, Bernd, Gänsbacher, Bernd, Hacein-Bey-Abina, Salima, Hacein-Bey-Abina, Salima, Hantraye, Philippe, Hantraye, Philippe, Haskins, Mark, Haskins, Mark, Hassig, Raymonde, Hassig, Raymonde, Hauser, Hansjörg, Hauser, Hansjörg, Heinz, Niels, Heinz, Niels, Händel, Eva-Maria, Händel, Eva-Maria, Ivics, Zoltán, Ivics, Zoltán, Izsvák, Zsuzsanna, Izsvák, Zsuzsanna, Jacobs, Andreas H., Jacobs, Andreas H., Jarmin, Susan, Jarmin, Susan, Jimenez, Veronica, Jimenez, Veronica, Kalle, Christof von, Kalle, Christof von, Kang, Jagjeet, Kang, Jagjeet, Kent, Alastair, Kent, Alastair, Khalaileh, Abed, Khalaileh, Abed, Kichler, Antoine, Kichler, Antoine, King, Nancy M.P., King, Nancy M.P., Klatzmann, David, Klatzmann, David, Kochanek, Stefan, Kochanek, Stefan, Kolodkin-Gal, Dror, Kolodkin-Gal, Dror, Koo, Taeyoung, Koo, Taeyoung, Kunicher, Nikolai, Kunicher, Nikolai, Lachmann, Kristina, Lachmann, Kristina, Laufs, Stephanie, Laufs, Stephanie, Lemaire, Stéphanie, Lemaire, Stéphanie, Lemoine, François, Lemoine, François, Lind, Göran, Lind, Göran, Lindenmaier, Werner, Lindenmaier, Werner, Linderoth, Bengt, Linderoth, Bengt, Lock, Martin, Lock, Martin, Lucas, Tanja, Lucas, Tanja, Luzzatto, Lucio, Luzzatto, Lucio, Macke, Lars, Macke, Lars, Maetzig, Tobias, Maetzig, Tobias, Maldiney, Thomas, Maldiney, Thomas, Malerba, Alberto, Malerba, Alberto, Mann, Christopher, Mann, Christopher, Marie, Corinne, Marie, Corinne, Marques Alves, Paula, Marques Alves, Paula, Merten, Otto-Wilhelm, Merten, Otto-Wilhelm, Meyring, Wilhelm, Meyring, Wilhelm, Mignet, Nathalie, Mignet, Nathalie, Mingozzi, Federico, Mingozzi, Federico, Mitrophanous, Kyriacos, Mitrophanous, Kyriacos, Modlich, Ute, Modlich, Ute, Monfared, Parisa, Monfared, Parisa, Montini, Eugenio, Montini, Eugenio, Moullier, Philippe, Moullier, Philippe, Naldini, Luigi, Naldini, Luigi, Nathwani, Amit C., Nathwani, Amit C., Nienhuis, Arthur W., Nienhuis, Arthur W., Palfi, Stéphane, Palfi, Stéphane, Panet, Amos, Panet, Amos, Peixoto, Cristina, Peixoto, Cristina, Pohl, Susanne, Pohl, Susanne, Popplewell, Linda, Popplewell, Linda, Pâques, Frédéric, Pâques, Frédéric, Raj, Deepak, Raj, Deepak, Ralph, R. Scott, Ralph, R. Scott, Reiss, Ulrike, Reiss, Ulrike, Richard, Cyrille, Richard, Cyrille, Rischmüller, Anja, Rischmüller, Anja, Rodrigues, Ana F., Rodrigues, Ana F., Rosenzwajg, Michelle, Rosenzwajg, Michelle, Santos, Jorge M., Santos, Jorge M., Schambach, Axel, Schambach, Axel, Schaser, Thomas, Schaser, Thomas, Scherman, Daniel, Scherman, Daniel, Schleef, Martin, Schleef, Martin, Schmeer, Marco, Schmeer, Marco, Schmidt, Manfred, Schmidt, Manfred, Schweizer, Matthias, Schweizer, Matthias, Schäfers, Sonja, Schäfers, Sonja, Seiger, Åke, Seiger, Åke, Simão, Daniel, Simão, Daniel, Six, Adrien, Six, Adrien, Smith, Alexander J, Smith, Alexander J, Smith, Alexander J., Smith, Alexander J., Smith, Julianne, Smith, Julianne, Snyder, Richard O., Snyder, Richard O., Sofia Coroadinha, Ana, Sofia Coroadinha, Ana, Sousa, Marcos F.Q., Sousa, Marcos F.Q., Suerth, Julia D., Suerth, Julia D., Sundström, Erik, Sundström, Erik, Tayeb, Shay, Tayeb, Shay, Thomas, Michael, Thomas, Michael, Thomas-Vaslin, Véronique, Thomas-Vaslin, Véronique, Tuddenham, Edward G.D., Tuddenham, Edward G.D., VandenDriessche, Thierry, VandenDriessche, Thierry, Verhoeyen, Els, Verhoeyen, Els, Verma, Inder M., Verma, Inder M., Viel, Thomas, Viel, Thomas, Waerzeggers, Yannic, Waerzeggers, Yannic, Wahlberg, Lars, Wahlberg, Lars, Winkeler, Alexandra, Winkeler, Alexandra, Wirth, Dagmar, Wirth, Dagmar, Ylä-Herttuala, Seppo, Ylä-Herttuala, Seppo, Zacchigna, Serena, Zacchigna, Serena, Zamir, Gidi, Zamir, Gidi, |
author_variant |
o c h och o c h och |
author_role |
VerfasserIn VerfasserIn |
author2 |
Aiuti, Alessandro, Aiuti, Alessandro, Ali, Robin R., Ali, Robin R., Alici, Evren, Alici, Evren, Almqvist, Per, Almqvist, Per, Annunziata, Patrizia, Annunziata, Patrizia, Anton, Martina, Anton, Martina, Artus, Alexandre, Artus, Alexandre, Athanasopoulos, Takis, Athanasopoulos, Takis, Aubourg, Patrick, Aubourg, Patrick, Auregan, Gwennaelle, Auregan, Gwennaelle, Auricchio, Alberto, Auricchio, Alberto, Bandeira, Vanessa, Bandeira, Vanessa, Bartholomae, Cynthia C., Bartholomae, Cynthia C., Baum, Christopher, Baum, Christopher, Bayart, Émilie, Bayart, Émilie, Bednarski, Christien, Bednarski, Christien, Bellier, Bertrand, Bellier, Bertrand, Biasco, Luca, Biasco, Luca, Bigey, Pascal, Bigey, Pascal, Blouin, Véronique, Blouin, Véronique, Bode, Juergen, Bode, Juergen, Bonvento, Gilles, Bonvento, Gilles, Bosch, Fatima, Bosch, Fatima, Bougnères, Pierre, Bougnères, Pierre, Brigida, Immacolata, Brigida, Immacolata, Broll, Sandra, Broll, Sandra, Buchholz, Christian J., Buchholz, Christian J., Bureau, Michel-Francis, Bureau, Michel-Francis, Bárcia, Rita N., Bárcia, Rita N., Callejas, David, Callejas, David, Carina Silva, Ana, Carina Silva, Ana, Carrondo, Manuel J.T., Carrondo, Manuel J.T., Cartier, Nathalie, Cartier, Nathalie, Cathomen, Toni, Cathomen, Toni, Cavazzana-Calvo, Marina, Cavazzana-Calvo, Marina, Chuah, Marinee K.L., Chuah, Marinee K.L., Cichutek, Klaus, Cichutek, Klaus, Cohen-Haguenauer, Odile, Cohen-Haguenauer, Odile, Colin, Angélique, Colin, Angélique, Cordova, Gonzalo, Cordova, Gonzalo, Coroadinha, Ana Sofia, Coroadinha, Ana Sofia, Cosset, François-Loïc, Cosset, François-Loïc, Cotugno, Gabriella, Cotugno, Gabriella, Cruz, Helder J.S, Cruz, Helder J.S, Cruz, Pedro E., Cruz, Pedro E., Darmon, Christophe, Darmon, Christophe, Davidoff, Andrew M., Davidoff, Andrew M., Dickson, George, Dickson, George, Dittmar, Kurt E.J., Dittmar, Kurt E.J., Draghia-Akli, Ruxandra, Draghia-Akli, Ruxandra, Dufour, Noëlle, Dufour, Noëlle, Duros, Caroline, Duros, Caroline, Déglon, Nicole, Déglon, Nicole, Dürner, Lydia, Dürner, Lydia, Eriksdotter-Jönhagen, Maria, Eriksdotter-Jönhagen, Maria, Escartin, Carole, Escartin, Carole, Escriou, Virginie, Escriou, Virginie, Eyjolfsdottir, Helga, Eyjolfsdottir, Helga, Faideau, Mathilde, Faideau, Mathilde, Fischer, Alain, Fischer, Alain, Foster, Helen, Foster, Helen, Foster, Keith, Foster, Keith, Gahrton, Gösta, Gahrton, Gösta, Galla, Melanie, Galla, Melanie, Galy, Anne, Galy, Anne, Gama-Norton, Leonor, Gama-Norton, Leonor, Garritsen, Henk S.P., Garritsen, Henk S.P., Georgiadis, Anastasios, Georgiadis, Anastasios, Giacca, Mauro, Giacca, Mauro, Gilljam, Mari, Gilljam, Mari, Gänsbacher, Bernd, Gänsbacher, Bernd, Hacein-Bey-Abina, Salima, Hacein-Bey-Abina, Salima, Hantraye, Philippe, Hantraye, Philippe, Haskins, Mark, Haskins, Mark, Hassig, Raymonde, Hassig, Raymonde, Hauser, Hansjörg, Hauser, Hansjörg, Heinz, Niels, Heinz, Niels, Händel, Eva-Maria, Händel, Eva-Maria, Ivics, Zoltán, Ivics, Zoltán, Izsvák, Zsuzsanna, Izsvák, Zsuzsanna, Jacobs, Andreas H., Jacobs, Andreas H., Jarmin, Susan, Jarmin, Susan, Jimenez, Veronica, Jimenez, Veronica, Kalle, Christof von, Kalle, Christof von, Kang, Jagjeet, Kang, Jagjeet, Kent, Alastair, Kent, Alastair, Khalaileh, Abed, Khalaileh, Abed, Kichler, Antoine, Kichler, Antoine, King, Nancy M.P., King, Nancy M.P., Klatzmann, David, Klatzmann, David, Kochanek, Stefan, Kochanek, Stefan, Kolodkin-Gal, Dror, Kolodkin-Gal, Dror, Koo, Taeyoung, Koo, Taeyoung, Kunicher, Nikolai, Kunicher, Nikolai, Lachmann, Kristina, Lachmann, Kristina, Laufs, Stephanie, Laufs, Stephanie, Lemaire, Stéphanie, Lemaire, Stéphanie, Lemoine, François, Lemoine, François, Lind, Göran, Lind, Göran, Lindenmaier, Werner, Lindenmaier, Werner, Linderoth, Bengt, Linderoth, Bengt, Lock, Martin, Lock, Martin, Lucas, Tanja, Lucas, Tanja, Luzzatto, Lucio, Luzzatto, Lucio, Macke, Lars, Macke, Lars, Maetzig, Tobias, Maetzig, Tobias, Maldiney, Thomas, Maldiney, Thomas, Malerba, Alberto, Malerba, Alberto, Mann, Christopher, Mann, Christopher, Marie, Corinne, Marie, Corinne, Marques Alves, Paula, Marques Alves, Paula, Merten, Otto-Wilhelm, Merten, Otto-Wilhelm, Meyring, Wilhelm, Meyring, Wilhelm, Mignet, Nathalie, Mignet, Nathalie, Mingozzi, Federico, Mingozzi, Federico, Mitrophanous, Kyriacos, Mitrophanous, Kyriacos, Modlich, Ute, Modlich, Ute, Monfared, Parisa, Monfared, Parisa, Montini, Eugenio, Montini, Eugenio, Moullier, Philippe, Moullier, Philippe, Naldini, Luigi, Naldini, Luigi, Nathwani, Amit C., Nathwani, Amit C., Nienhuis, Arthur W., Nienhuis, Arthur W., Palfi, Stéphane, Palfi, Stéphane, Panet, Amos, Panet, Amos, Peixoto, Cristina, Peixoto, Cristina, Pohl, Susanne, Pohl, Susanne, Popplewell, Linda, Popplewell, Linda, Pâques, Frédéric, Pâques, Frédéric, Raj, Deepak, Raj, Deepak, Ralph, R. Scott, Ralph, R. Scott, Reiss, Ulrike, Reiss, Ulrike, Richard, Cyrille, Richard, Cyrille, Rischmüller, Anja, Rischmüller, Anja, Rodrigues, Ana F., Rodrigues, Ana F., Rosenzwajg, Michelle, Rosenzwajg, Michelle, Santos, Jorge M., Santos, Jorge M., Schambach, Axel, Schambach, Axel, Schaser, Thomas, Schaser, Thomas, Scherman, Daniel, Scherman, Daniel, Schleef, Martin, Schleef, Martin, Schmeer, Marco, Schmeer, Marco, Schmidt, Manfred, Schmidt, Manfred, Schweizer, Matthias, Schweizer, Matthias, Schäfers, Sonja, Schäfers, Sonja, Seiger, Åke, Seiger, Åke, Simão, Daniel, Simão, Daniel, Six, Adrien, Six, Adrien, Smith, Alexander J, Smith, Alexander J, Smith, Alexander J., Smith, Alexander J., Smith, Julianne, Smith, Julianne, Snyder, Richard O., Snyder, Richard O., Sofia Coroadinha, Ana, Sofia Coroadinha, Ana, Sousa, Marcos F.Q., Sousa, Marcos F.Q., Suerth, Julia D., Suerth, Julia D., Sundström, Erik, Sundström, Erik, Tayeb, Shay, Tayeb, Shay, Thomas, Michael, Thomas, Michael, Thomas-Vaslin, Véronique, Thomas-Vaslin, Véronique, Tuddenham, Edward G.D., Tuddenham, Edward G.D., VandenDriessche, Thierry, VandenDriessche, Thierry, Verhoeyen, Els, Verhoeyen, Els, Verma, Inder M., Verma, Inder M., Viel, Thomas, Viel, Thomas, Waerzeggers, Yannic, Waerzeggers, Yannic, Wahlberg, Lars, Wahlberg, Lars, Winkeler, Alexandra, Winkeler, Alexandra, Wirth, Dagmar, Wirth, Dagmar, Ylä-Herttuala, Seppo, Ylä-Herttuala, Seppo, Zacchigna, Serena, Zacchigna, Serena, Zamir, Gidi, Zamir, Gidi, |
author2_variant |
a a aa a a aa r r a rr rra r r a rr rra e a ea e a ea p a pa p a pa p a pa p a pa m a ma m a ma a a aa a a aa t a ta t a ta p a pa p a pa g a ga g a ga a a aa a a aa v b vb v b vb c c b cc ccb c c b cc ccb c b cb c b cb é b éb é b éb c b cb c b cb b b bb b b bb l b lb l b lb p b pb p b pb v b vb v b vb j b jb j b jb g b gb g b gb f b fb f b fb p b pb p b pb i b ib i b ib s b sb s b sb c j b cj cjb c j b cj cjb m f b mfb m f b mfb r n b rn rnb r n b rn rnb d c dc d c dc s a c sa sac s a c sa sac m j c mj mjc m j c mj mjc n c nc n c nc t c tc t c tc m c c mcc m c c mcc m k c mk mkc m k c mk mkc k c kc k c kc o c h och o c h och a c ac a c ac g c gc g c gc a s c as asc a s c as asc f l c flc f l c flc g c gc g c gc h j c hj hjc h j c hj hjc p e c pe pec p e c pe pec c d cd c d cd a m d am amd a m d am amd g d gd g d gd k e d ke ked k e d ke ked r d a rda r d a rda n d nd n d nd c d cd c d cd n d nd n d nd l d ld l d ld m e j mej m e j mej c e ce c e ce v e ve v e ve h e he h e he m f mf m f mf a f af a f af h f hf h f hf k f kf k f kf g g gg g g gg m g mg m g mg a g ag a g ag l g n lgn l g n lgn h s g hs hsg h s g hs hsg a g ag a g ag m g mg m g mg m g mg m g mg b g bg b g bg s h b shb s h b shb p h ph p h ph m h mh m h mh r h rh r h rh h h hh h h hh n h nh n h nh e m h emh e m h emh z i zi z i zi z i zi z i zi a h j ah ahj a h j ah ahj s j sj s j sj v j vj v j vj c v k cv cvk c v k cv cvk j k jk j k jk a k ak a k ak a k ak a k ak a k ak a k ak n m k nm nmk n m k nm nmk d k dk d k dk s k sk s k sk d k g dkg d k g dkg t k tk t k tk n k nk n k nk k l kl k l kl s l sl s l sl s l sl s l sl f l fl f l fl g l gl g l gl w l wl w l wl b l bl b l bl m l ml m l ml t l tl t l tl l l ll l l ll l m lm l m lm t m tm t m tm t m tm t m tm a m am a m am c m cm c m cm c m cm c m cm a p m ap apm a p m ap apm o w m owm o w m owm w m wm w m wm n m nm n m nm f m fm f m fm k m km k m km u m um u m um p m pm p m pm e m em e m em p m pm p m pm l n ln l n ln a c n ac acn a c n ac acn a w n aw awn a w n aw awn s p sp s p sp a p ap a p ap c p cp c p cp s p sp s p sp l p lp l p lp f p fp f p fp d r dr d r dr r s r rs rsr r s r rs rsr u r ur u r ur c r cr c r cr a r ar a r ar a f r af afr a f r af afr m r mr m r mr j m s jm jms j m s jm jms a s as a s as t s ts t s ts d s ds d s ds m s ms m s ms m s ms m s ms m s ms m s ms m s ms m s ms s s ss s s ss å s ås å s ås d s ds d s ds a s as a s as a j s aj ajs a j s aj ajs a j s aj ajs a j s aj ajs j s js j s js r o s ro ros r o s ro ros c a s ca cas c a s ca cas m f s mf mfs m f s mf mfs j d s jd jds j d s jd jds e s es e s es s t st s t st m t mt m t mt v t v vtv v t v vtv e g t eg egt e g t eg egt t v tv t v tv e v ev e v ev i m v im imv i m v im imv t v tv t v tv y w yw y w yw l w lw l w lw a w aw a w aw d w dw d w dw s y h syh s y h syh s z sz s z sz g z gz g z gz |
author2_role |
MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR MitwirkendeR |
author_sort |
Cohen-Haguenauer, Odile, |
title |
The CliniBook : Clinical gene transfer state of the art / |
title_sub |
Clinical gene transfer state of the art / |
title_full |
The CliniBook : Clinical gene transfer state of the art / Odile Cohen-Haguenauer. |
title_fullStr |
The CliniBook : Clinical gene transfer state of the art / Odile Cohen-Haguenauer. |
title_full_unstemmed |
The CliniBook : Clinical gene transfer state of the art / Odile Cohen-Haguenauer. |
title_auth |
The CliniBook : Clinical gene transfer state of the art / |
title_alt |
Frontmatter -- CliniGene Partners and Boards -- ACKNOWLEDGMENTS -- List of authors -- Contents -- INTRODUCTION -- In-1 Foreword -- In-2 Main achievements and prospects downstream of the CliniGene-NoE -- PART I: TECHNOLOGIES AND PRE-CLINICAL STUDIES -- TECHNOLOGIES - Highlights on AAV mediated gene transfer -- A1-1 Highlights on AAV mediated gene transfer: introduction -- A1-2 Preclinical studies of AAV gene therapy for inherited retinal dystrophies -- A1-3 AAV-mediated gene therapy for MPS VI -- A1-4 Microdystrophin and myostatin gene therapy for Duchenne muscular dystrophy using adeno-associated virus vectors -- A1-5 AAV gene therapy for cardiovascular disorders -- A1-6 AAV gene therapy for diabetes mellitus -- A1-7 Approaches to large scale production of AAV-vectors -- A1-8 Reference materials for the characterization of adeno-associated viral vectors -- TECHNOLOGIES - Retrovirus mediated gene transfer state-of-the-art -- A2-1 Highlights on retrovirus mediated gene transfer -- A2-2 Retroviral vector development: reducing genotoxicity of integrated DNA and creating virus-like particles for transient cell modification -- A2-3 Replication-competent y-retroviral vectors for tumor therapy -- A2-4 Modular retroviral producer cell lines -- TECHNOLOGIES - Highlights on lentivirus mediated gene transfer -- A3-1 Introduction -- A3-2 MicroRNAs detargeting technology in the context of CNS applications -- A3-3 Development of SIVsmmPBj vectors for gene transfer into myeloid cells -- A3-4 Insulated retrovirus vectors using novel synthetic genetic insulator elements to circumvent enhancer-mediated genotoxicity -- A3-5 Facing the challenges of downstream processing of lentiviral vectors -- A3-6 Restrictions and requirements for stable lentiviral vector production in HEK293 cells -- A3-7 Novel lentiviral vector pseudotypes for stable gene transfer into resting hematopoietic cells -- TECHNOLOGIES - Highlights on gene-modified cell therapy -- A4-1 Cell therapy Introduction -- A4-2 Ex-vivo expansion of human mesenchymal stem cells -- A4-3 Closed bag cultivation systems for the production of gene modified dendritic cells and MSC for clinical use -- A4-4 Genetically modified NK cells for cancer treatment: facts and visions -- A4-5 Regulatory T lymphocyte depletion for cancer immunotherapies -- A4-6 Gene therapy of Fanconi’s anaemia aplastic syndrome -- TECHNOLOGIES - Adenovirus mediated gene transfer: current developments -- A5-1 Overview on adenovirus vectors -- A5-2 Tumour barriers influencing adenovirus vector delivery and therapeutic efficacy -- A5-3 Tumor imaging with adenoviral vectors -- A5-4 Treatment of brain tumors with adenoviruses: preclinical development -- A5-5 Production and purification of Ad vectors: current status and future needs for adenovirus vector production -- TECHNOLOGIES - Non-viral based gene transfer: a new era -- A6-1 Non viral plasmid delivery and imaging of transgene expression A6-1 Non viral plasmid delivery and imaging of transgene expression -- A6-2 Overview of novel plasmid vectors and preclinical applications -- A6-3 Filling a gap: S/MAR-based replicating minicircles -- A6-4 Manufacturing and QC of plasmid based vectors -- A6-5 Sleeping Beauty transposon based gene therapy -- A6-6 Development of minicircle vectors -- A6-7 Exon skipping therapy for DMD using antisense oligomer technology -- TECHNOLOGIES - Highlights on emerging technologies, iPS induction and genetic stability -- A7-1 Induction of pluripotency from adult somatic cells: a review -- A7-2 Genetic modification of adult stem cells and induced pluripotent stem cells with emerging transposon technologies -- A7-3 Targeted genome engineering approaches based on rare-cutting endonucleases: a tentative summary -- A7-4 Targeted genome modifications with designer nucleases -- PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - Preclinical assessment tools -- B1-1 Preclinical assessment tools: imaging gene transfer to the brain -- B1-2 Persistent luminescence nanoparticles for in vivo imaging: characteristics and targeting -- B1-3 Ex-vivo evaluation of gene-transfer vectors: efficacy, tropism and safety -- PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - General biosafety: immune responses, immunotoxicity and genotoxicity -- B2-1 Assessing and taming unwanted immune responses induced by AAV gene transfer: current status, ongoing questions and future prospects -- B2-2 Predicting immune responses to viral vectors and transgenes in gene therapy and vaccination: the coming of systems biology -- B2-3 Biosafety analysis in preclinical and clinical studies -- PART II Clinical trials and regulatory issues -- CLINICAL TRIALS -- C1-1 A clinical trial of AAV-mediated gene therapy for Leber congenital amaurosis 2 -- C1-2 Gene therapy for X-linked adrenoleukodystrophy based on lentiviral correction of hematopoietic stem cells -- C1-3 Immune reconstitution after gene therapy for adenosine deaminase severe combined immunodeficiency (ADA-SCID) -- C1-4 Gene therapy in Alzheimer disease patients -- C1-5 Cardiovascular gene therapy trials -- C1-6 AAV-mediated gene therapy for haemophilia B -- C1-7 ProSavin®: a lentiviral vector approach for the treatment of Parkinson’s disease -- ETHICAL AND REGULATORY ISSUES -- C2-1 Ethics in translation from research to therapy -- C2-2 Centralised regulation of gene therapy in Europe -- C2-3 The necessity for data sharing towards advancement of clinical translation Building up sample IMPD* and substantiating master files -- INTEGRATION AND DISSEMINATION -- C3-1 European Union support to gene transfer and gene therapy -- C3-2 Database of clinical trials -- C3-3 CliniGene and ESGCT shared vision for gene therapy in Europe: past, present and future prospects -- AUTHOR INDEX |
title_new |
The CliniBook : |
title_sort |
the clinibook : clinical gene transfer state of the art / |
publisher |
EDP Sciences, |
publishDate |
2012 |
physical |
1 online resource (589 p.) |
contents |
Frontmatter -- CliniGene Partners and Boards -- ACKNOWLEDGMENTS -- List of authors -- Contents -- INTRODUCTION -- In-1 Foreword -- In-2 Main achievements and prospects downstream of the CliniGene-NoE -- PART I: TECHNOLOGIES AND PRE-CLINICAL STUDIES -- TECHNOLOGIES - Highlights on AAV mediated gene transfer -- A1-1 Highlights on AAV mediated gene transfer: introduction -- A1-2 Preclinical studies of AAV gene therapy for inherited retinal dystrophies -- A1-3 AAV-mediated gene therapy for MPS VI -- A1-4 Microdystrophin and myostatin gene therapy for Duchenne muscular dystrophy using adeno-associated virus vectors -- A1-5 AAV gene therapy for cardiovascular disorders -- A1-6 AAV gene therapy for diabetes mellitus -- A1-7 Approaches to large scale production of AAV-vectors -- A1-8 Reference materials for the characterization of adeno-associated viral vectors -- TECHNOLOGIES - Retrovirus mediated gene transfer state-of-the-art -- A2-1 Highlights on retrovirus mediated gene transfer -- A2-2 Retroviral vector development: reducing genotoxicity of integrated DNA and creating virus-like particles for transient cell modification -- A2-3 Replication-competent y-retroviral vectors for tumor therapy -- A2-4 Modular retroviral producer cell lines -- TECHNOLOGIES - Highlights on lentivirus mediated gene transfer -- A3-1 Introduction -- A3-2 MicroRNAs detargeting technology in the context of CNS applications -- A3-3 Development of SIVsmmPBj vectors for gene transfer into myeloid cells -- A3-4 Insulated retrovirus vectors using novel synthetic genetic insulator elements to circumvent enhancer-mediated genotoxicity -- A3-5 Facing the challenges of downstream processing of lentiviral vectors -- A3-6 Restrictions and requirements for stable lentiviral vector production in HEK293 cells -- A3-7 Novel lentiviral vector pseudotypes for stable gene transfer into resting hematopoietic cells -- TECHNOLOGIES - Highlights on gene-modified cell therapy -- A4-1 Cell therapy Introduction -- A4-2 Ex-vivo expansion of human mesenchymal stem cells -- A4-3 Closed bag cultivation systems for the production of gene modified dendritic cells and MSC for clinical use -- A4-4 Genetically modified NK cells for cancer treatment: facts and visions -- A4-5 Regulatory T lymphocyte depletion for cancer immunotherapies -- A4-6 Gene therapy of Fanconi’s anaemia aplastic syndrome -- TECHNOLOGIES - Adenovirus mediated gene transfer: current developments -- A5-1 Overview on adenovirus vectors -- A5-2 Tumour barriers influencing adenovirus vector delivery and therapeutic efficacy -- A5-3 Tumor imaging with adenoviral vectors -- A5-4 Treatment of brain tumors with adenoviruses: preclinical development -- A5-5 Production and purification of Ad vectors: current status and future needs for adenovirus vector production -- TECHNOLOGIES - Non-viral based gene transfer: a new era -- A6-1 Non viral plasmid delivery and imaging of transgene expression A6-1 Non viral plasmid delivery and imaging of transgene expression -- A6-2 Overview of novel plasmid vectors and preclinical applications -- A6-3 Filling a gap: S/MAR-based replicating minicircles -- A6-4 Manufacturing and QC of plasmid based vectors -- A6-5 Sleeping Beauty transposon based gene therapy -- A6-6 Development of minicircle vectors -- A6-7 Exon skipping therapy for DMD using antisense oligomer technology -- TECHNOLOGIES - Highlights on emerging technologies, iPS induction and genetic stability -- A7-1 Induction of pluripotency from adult somatic cells: a review -- A7-2 Genetic modification of adult stem cells and induced pluripotent stem cells with emerging transposon technologies -- A7-3 Targeted genome engineering approaches based on rare-cutting endonucleases: a tentative summary -- A7-4 Targeted genome modifications with designer nucleases -- PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - Preclinical assessment tools -- B1-1 Preclinical assessment tools: imaging gene transfer to the brain -- B1-2 Persistent luminescence nanoparticles for in vivo imaging: characteristics and targeting -- B1-3 Ex-vivo evaluation of gene-transfer vectors: efficacy, tropism and safety -- PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - General biosafety: immune responses, immunotoxicity and genotoxicity -- B2-1 Assessing and taming unwanted immune responses induced by AAV gene transfer: current status, ongoing questions and future prospects -- B2-2 Predicting immune responses to viral vectors and transgenes in gene therapy and vaccination: the coming of systems biology -- B2-3 Biosafety analysis in preclinical and clinical studies -- PART II Clinical trials and regulatory issues -- CLINICAL TRIALS -- C1-1 A clinical trial of AAV-mediated gene therapy for Leber congenital amaurosis 2 -- C1-2 Gene therapy for X-linked adrenoleukodystrophy based on lentiviral correction of hematopoietic stem cells -- C1-3 Immune reconstitution after gene therapy for adenosine deaminase severe combined immunodeficiency (ADA-SCID) -- C1-4 Gene therapy in Alzheimer disease patients -- C1-5 Cardiovascular gene therapy trials -- C1-6 AAV-mediated gene therapy for haemophilia B -- C1-7 ProSavin®: a lentiviral vector approach for the treatment of Parkinson’s disease -- ETHICAL AND REGULATORY ISSUES -- C2-1 Ethics in translation from research to therapy -- C2-2 Centralised regulation of gene therapy in Europe -- C2-3 The necessity for data sharing towards advancement of clinical translation Building up sample IMPD* and substantiating master files -- INTEGRATION AND DISSEMINATION -- C3-1 European Union support to gene transfer and gene therapy -- C3-2 Database of clinical trials -- C3-3 CliniGene and ESGCT shared vision for gene therapy in Europe: past, present and future prospects -- AUTHOR INDEX |
isbn |
9782842542375 9783111024110 |
url |
https://doi.org/10.1051/978-2-84254-237-5 https://www.degruyter.com/isbn/9782842542375 https://www.degruyter.com/document/cover/isbn/9782842542375/original |
illustrated |
Not Illustrated |
doi_str_mv |
10.1051/978-2-84254-237-5 |
oclc_num |
834607434 |
work_keys_str_mv |
AT cohenhaguenauerodile theclinibookclinicalgenetransferstateoftheart AT aiutialessandro theclinibookclinicalgenetransferstateoftheart AT alirobinr theclinibookclinicalgenetransferstateoftheart AT alicievren theclinibookclinicalgenetransferstateoftheart AT almqvistper theclinibookclinicalgenetransferstateoftheart AT annunziatapatrizia theclinibookclinicalgenetransferstateoftheart AT antonmartina theclinibookclinicalgenetransferstateoftheart AT artusalexandre theclinibookclinicalgenetransferstateoftheart AT athanasopoulostakis theclinibookclinicalgenetransferstateoftheart AT aubourgpatrick theclinibookclinicalgenetransferstateoftheart AT auregangwennaelle theclinibookclinicalgenetransferstateoftheart AT auricchioalberto theclinibookclinicalgenetransferstateoftheart AT bandeiravanessa theclinibookclinicalgenetransferstateoftheart AT bartholomaecynthiac theclinibookclinicalgenetransferstateoftheart AT baumchristopher theclinibookclinicalgenetransferstateoftheart AT bayartemilie theclinibookclinicalgenetransferstateoftheart AT bednarskichristien theclinibookclinicalgenetransferstateoftheart AT bellierbertrand theclinibookclinicalgenetransferstateoftheart AT biascoluca theclinibookclinicalgenetransferstateoftheart AT bigeypascal theclinibookclinicalgenetransferstateoftheart AT blouinveronique theclinibookclinicalgenetransferstateoftheart AT bodejuergen theclinibookclinicalgenetransferstateoftheart AT bonventogilles theclinibookclinicalgenetransferstateoftheart AT boschfatima theclinibookclinicalgenetransferstateoftheart AT bougnerespierre theclinibookclinicalgenetransferstateoftheart AT brigidaimmacolata theclinibookclinicalgenetransferstateoftheart AT brollsandra theclinibookclinicalgenetransferstateoftheart AT buchholzchristianj theclinibookclinicalgenetransferstateoftheart AT bureaumichelfrancis theclinibookclinicalgenetransferstateoftheart AT barciaritan theclinibookclinicalgenetransferstateoftheart AT callejasdavid theclinibookclinicalgenetransferstateoftheart AT carinasilvaana theclinibookclinicalgenetransferstateoftheart AT carrondomanueljt theclinibookclinicalgenetransferstateoftheart AT cartiernathalie theclinibookclinicalgenetransferstateoftheart AT cathomentoni theclinibookclinicalgenetransferstateoftheart AT cavazzanacalvomarina theclinibookclinicalgenetransferstateoftheart AT chuahmarineekl theclinibookclinicalgenetransferstateoftheart AT cichutekklaus theclinibookclinicalgenetransferstateoftheart AT colinangelique theclinibookclinicalgenetransferstateoftheart AT cordovagonzalo theclinibookclinicalgenetransferstateoftheart AT coroadinhaanasofia theclinibookclinicalgenetransferstateoftheart AT cossetfrancoisloic theclinibookclinicalgenetransferstateoftheart AT cotugnogabriella theclinibookclinicalgenetransferstateoftheart AT cruzhelderjs theclinibookclinicalgenetransferstateoftheart AT cruzpedroe theclinibookclinicalgenetransferstateoftheart AT darmonchristophe theclinibookclinicalgenetransferstateoftheart AT davidoffandrewm theclinibookclinicalgenetransferstateoftheart AT dicksongeorge theclinibookclinicalgenetransferstateoftheart AT dittmarkurtej theclinibookclinicalgenetransferstateoftheart AT draghiaakliruxandra theclinibookclinicalgenetransferstateoftheart AT dufournoelle theclinibookclinicalgenetransferstateoftheart AT duroscaroline theclinibookclinicalgenetransferstateoftheart AT deglonnicole theclinibookclinicalgenetransferstateoftheart AT durnerlydia theclinibookclinicalgenetransferstateoftheart AT eriksdotterjonhagenmaria theclinibookclinicalgenetransferstateoftheart AT escartincarole theclinibookclinicalgenetransferstateoftheart AT escriouvirginie theclinibookclinicalgenetransferstateoftheart AT eyjolfsdottirhelga theclinibookclinicalgenetransferstateoftheart AT faideaumathilde theclinibookclinicalgenetransferstateoftheart AT fischeralain theclinibookclinicalgenetransferstateoftheart AT fosterhelen theclinibookclinicalgenetransferstateoftheart AT fosterkeith theclinibookclinicalgenetransferstateoftheart AT gahrtongosta theclinibookclinicalgenetransferstateoftheart AT gallamelanie theclinibookclinicalgenetransferstateoftheart AT galyanne theclinibookclinicalgenetransferstateoftheart AT gamanortonleonor theclinibookclinicalgenetransferstateoftheart AT garritsenhenksp theclinibookclinicalgenetransferstateoftheart AT georgiadisanastasios theclinibookclinicalgenetransferstateoftheart AT giaccamauro theclinibookclinicalgenetransferstateoftheart AT gilljammari theclinibookclinicalgenetransferstateoftheart AT gansbacherbernd theclinibookclinicalgenetransferstateoftheart AT haceinbeyabinasalima theclinibookclinicalgenetransferstateoftheart AT hantrayephilippe theclinibookclinicalgenetransferstateoftheart AT haskinsmark theclinibookclinicalgenetransferstateoftheart AT hassigraymonde theclinibookclinicalgenetransferstateoftheart AT hauserhansjorg theclinibookclinicalgenetransferstateoftheart AT heinzniels theclinibookclinicalgenetransferstateoftheart AT handelevamaria theclinibookclinicalgenetransferstateoftheart AT ivicszoltan theclinibookclinicalgenetransferstateoftheart AT izsvakzsuzsanna theclinibookclinicalgenetransferstateoftheart AT jacobsandreash theclinibookclinicalgenetransferstateoftheart AT jarminsusan theclinibookclinicalgenetransferstateoftheart AT jimenezveronica theclinibookclinicalgenetransferstateoftheart AT kallechristofvon theclinibookclinicalgenetransferstateoftheart AT kangjagjeet theclinibookclinicalgenetransferstateoftheart AT kentalastair theclinibookclinicalgenetransferstateoftheart AT khalailehabed theclinibookclinicalgenetransferstateoftheart AT kichlerantoine theclinibookclinicalgenetransferstateoftheart AT kingnancymp theclinibookclinicalgenetransferstateoftheart AT klatzmanndavid theclinibookclinicalgenetransferstateoftheart AT kochanekstefan theclinibookclinicalgenetransferstateoftheart AT kolodkingaldror theclinibookclinicalgenetransferstateoftheart AT kootaeyoung theclinibookclinicalgenetransferstateoftheart AT kunichernikolai theclinibookclinicalgenetransferstateoftheart AT lachmannkristina theclinibookclinicalgenetransferstateoftheart AT laufsstephanie theclinibookclinicalgenetransferstateoftheart AT lemairestephanie theclinibookclinicalgenetransferstateoftheart AT lemoinefrancois theclinibookclinicalgenetransferstateoftheart AT lindgoran theclinibookclinicalgenetransferstateoftheart AT lindenmaierwerner theclinibookclinicalgenetransferstateoftheart AT linderothbengt theclinibookclinicalgenetransferstateoftheart AT lockmartin theclinibookclinicalgenetransferstateoftheart AT lucastanja theclinibookclinicalgenetransferstateoftheart AT luzzattolucio theclinibookclinicalgenetransferstateoftheart AT mackelars theclinibookclinicalgenetransferstateoftheart AT maetzigtobias theclinibookclinicalgenetransferstateoftheart AT maldineythomas theclinibookclinicalgenetransferstateoftheart AT malerbaalberto theclinibookclinicalgenetransferstateoftheart AT mannchristopher theclinibookclinicalgenetransferstateoftheart AT mariecorinne theclinibookclinicalgenetransferstateoftheart AT marquesalvespaula theclinibookclinicalgenetransferstateoftheart AT mertenottowilhelm theclinibookclinicalgenetransferstateoftheart AT meyringwilhelm theclinibookclinicalgenetransferstateoftheart AT mignetnathalie theclinibookclinicalgenetransferstateoftheart AT mingozzifederico theclinibookclinicalgenetransferstateoftheart AT mitrophanouskyriacos theclinibookclinicalgenetransferstateoftheart AT modlichute theclinibookclinicalgenetransferstateoftheart AT monfaredparisa theclinibookclinicalgenetransferstateoftheart AT montinieugenio theclinibookclinicalgenetransferstateoftheart AT moullierphilippe theclinibookclinicalgenetransferstateoftheart AT naldiniluigi theclinibookclinicalgenetransferstateoftheart AT nathwaniamitc theclinibookclinicalgenetransferstateoftheart AT nienhuisarthurw theclinibookclinicalgenetransferstateoftheart AT palfistephane theclinibookclinicalgenetransferstateoftheart AT panetamos theclinibookclinicalgenetransferstateoftheart AT peixotocristina theclinibookclinicalgenetransferstateoftheart AT pohlsusanne theclinibookclinicalgenetransferstateoftheart AT popplewelllinda theclinibookclinicalgenetransferstateoftheart AT paquesfrederic theclinibookclinicalgenetransferstateoftheart AT rajdeepak theclinibookclinicalgenetransferstateoftheart AT ralphrscott theclinibookclinicalgenetransferstateoftheart AT reissulrike theclinibookclinicalgenetransferstateoftheart AT richardcyrille theclinibookclinicalgenetransferstateoftheart AT rischmulleranja theclinibookclinicalgenetransferstateoftheart AT rodriguesanaf theclinibookclinicalgenetransferstateoftheart AT rosenzwajgmichelle theclinibookclinicalgenetransferstateoftheart AT santosjorgem theclinibookclinicalgenetransferstateoftheart AT schambachaxel theclinibookclinicalgenetransferstateoftheart AT schaserthomas theclinibookclinicalgenetransferstateoftheart AT schermandaniel theclinibookclinicalgenetransferstateoftheart AT schleefmartin theclinibookclinicalgenetransferstateoftheart AT schmeermarco theclinibookclinicalgenetransferstateoftheart AT schmidtmanfred theclinibookclinicalgenetransferstateoftheart AT schweizermatthias theclinibookclinicalgenetransferstateoftheart AT schaferssonja theclinibookclinicalgenetransferstateoftheart AT seigerake theclinibookclinicalgenetransferstateoftheart AT simaodaniel theclinibookclinicalgenetransferstateoftheart AT sixadrien theclinibookclinicalgenetransferstateoftheart AT smithalexanderj theclinibookclinicalgenetransferstateoftheart AT smithjulianne theclinibookclinicalgenetransferstateoftheart AT snyderrichardo theclinibookclinicalgenetransferstateoftheart AT sofiacoroadinhaana theclinibookclinicalgenetransferstateoftheart AT sousamarcosfq theclinibookclinicalgenetransferstateoftheart AT suerthjuliad theclinibookclinicalgenetransferstateoftheart AT sundstromerik theclinibookclinicalgenetransferstateoftheart AT tayebshay theclinibookclinicalgenetransferstateoftheart AT thomasmichael theclinibookclinicalgenetransferstateoftheart AT thomasvaslinveronique theclinibookclinicalgenetransferstateoftheart AT tuddenhamedwardgd theclinibookclinicalgenetransferstateoftheart AT vandendriesschethierry theclinibookclinicalgenetransferstateoftheart AT verhoeyenels theclinibookclinicalgenetransferstateoftheart AT vermainderm theclinibookclinicalgenetransferstateoftheart AT vielthomas theclinibookclinicalgenetransferstateoftheart AT waerzeggersyannic theclinibookclinicalgenetransferstateoftheart AT wahlberglars theclinibookclinicalgenetransferstateoftheart AT winkeleralexandra theclinibookclinicalgenetransferstateoftheart AT wirthdagmar theclinibookclinicalgenetransferstateoftheart AT ylaherttualaseppo theclinibookclinicalgenetransferstateoftheart AT zacchignaserena theclinibookclinicalgenetransferstateoftheart AT zamirgidi theclinibookclinicalgenetransferstateoftheart AT cohenhaguenauerodile clinibookclinicalgenetransferstateoftheart AT aiutialessandro clinibookclinicalgenetransferstateoftheart AT alirobinr clinibookclinicalgenetransferstateoftheart AT alicievren clinibookclinicalgenetransferstateoftheart AT almqvistper clinibookclinicalgenetransferstateoftheart AT annunziatapatrizia clinibookclinicalgenetransferstateoftheart AT antonmartina clinibookclinicalgenetransferstateoftheart AT artusalexandre clinibookclinicalgenetransferstateoftheart AT athanasopoulostakis clinibookclinicalgenetransferstateoftheart AT aubourgpatrick clinibookclinicalgenetransferstateoftheart AT auregangwennaelle clinibookclinicalgenetransferstateoftheart AT auricchioalberto clinibookclinicalgenetransferstateoftheart AT bandeiravanessa clinibookclinicalgenetransferstateoftheart AT bartholomaecynthiac clinibookclinicalgenetransferstateoftheart AT baumchristopher clinibookclinicalgenetransferstateoftheart AT bayartemilie clinibookclinicalgenetransferstateoftheart AT bednarskichristien clinibookclinicalgenetransferstateoftheart AT bellierbertrand clinibookclinicalgenetransferstateoftheart AT biascoluca clinibookclinicalgenetransferstateoftheart AT bigeypascal clinibookclinicalgenetransferstateoftheart AT blouinveronique clinibookclinicalgenetransferstateoftheart AT bodejuergen clinibookclinicalgenetransferstateoftheart AT bonventogilles clinibookclinicalgenetransferstateoftheart AT boschfatima clinibookclinicalgenetransferstateoftheart AT bougnerespierre clinibookclinicalgenetransferstateoftheart AT brigidaimmacolata clinibookclinicalgenetransferstateoftheart AT brollsandra clinibookclinicalgenetransferstateoftheart AT buchholzchristianj clinibookclinicalgenetransferstateoftheart AT bureaumichelfrancis clinibookclinicalgenetransferstateoftheart AT barciaritan clinibookclinicalgenetransferstateoftheart AT callejasdavid clinibookclinicalgenetransferstateoftheart AT carinasilvaana clinibookclinicalgenetransferstateoftheart AT carrondomanueljt clinibookclinicalgenetransferstateoftheart AT cartiernathalie clinibookclinicalgenetransferstateoftheart AT cathomentoni clinibookclinicalgenetransferstateoftheart AT cavazzanacalvomarina clinibookclinicalgenetransferstateoftheart AT chuahmarineekl clinibookclinicalgenetransferstateoftheart AT cichutekklaus clinibookclinicalgenetransferstateoftheart AT colinangelique clinibookclinicalgenetransferstateoftheart AT cordovagonzalo clinibookclinicalgenetransferstateoftheart AT coroadinhaanasofia clinibookclinicalgenetransferstateoftheart AT cossetfrancoisloic clinibookclinicalgenetransferstateoftheart AT cotugnogabriella clinibookclinicalgenetransferstateoftheart AT cruzhelderjs clinibookclinicalgenetransferstateoftheart AT cruzpedroe clinibookclinicalgenetransferstateoftheart AT darmonchristophe clinibookclinicalgenetransferstateoftheart AT davidoffandrewm clinibookclinicalgenetransferstateoftheart AT dicksongeorge clinibookclinicalgenetransferstateoftheart AT dittmarkurtej clinibookclinicalgenetransferstateoftheart AT draghiaakliruxandra clinibookclinicalgenetransferstateoftheart AT dufournoelle clinibookclinicalgenetransferstateoftheart AT duroscaroline clinibookclinicalgenetransferstateoftheart AT deglonnicole clinibookclinicalgenetransferstateoftheart AT durnerlydia clinibookclinicalgenetransferstateoftheart AT eriksdotterjonhagenmaria clinibookclinicalgenetransferstateoftheart AT escartincarole clinibookclinicalgenetransferstateoftheart AT escriouvirginie clinibookclinicalgenetransferstateoftheart AT eyjolfsdottirhelga clinibookclinicalgenetransferstateoftheart AT faideaumathilde clinibookclinicalgenetransferstateoftheart AT fischeralain clinibookclinicalgenetransferstateoftheart AT fosterhelen clinibookclinicalgenetransferstateoftheart AT fosterkeith clinibookclinicalgenetransferstateoftheart AT gahrtongosta clinibookclinicalgenetransferstateoftheart AT gallamelanie clinibookclinicalgenetransferstateoftheart AT galyanne clinibookclinicalgenetransferstateoftheart AT gamanortonleonor clinibookclinicalgenetransferstateoftheart AT garritsenhenksp clinibookclinicalgenetransferstateoftheart AT georgiadisanastasios clinibookclinicalgenetransferstateoftheart AT giaccamauro clinibookclinicalgenetransferstateoftheart AT gilljammari clinibookclinicalgenetransferstateoftheart AT gansbacherbernd clinibookclinicalgenetransferstateoftheart AT haceinbeyabinasalima clinibookclinicalgenetransferstateoftheart AT hantrayephilippe clinibookclinicalgenetransferstateoftheart AT haskinsmark clinibookclinicalgenetransferstateoftheart AT hassigraymonde clinibookclinicalgenetransferstateoftheart AT hauserhansjorg clinibookclinicalgenetransferstateoftheart AT heinzniels clinibookclinicalgenetransferstateoftheart AT handelevamaria clinibookclinicalgenetransferstateoftheart AT ivicszoltan clinibookclinicalgenetransferstateoftheart AT izsvakzsuzsanna clinibookclinicalgenetransferstateoftheart AT jacobsandreash clinibookclinicalgenetransferstateoftheart AT jarminsusan clinibookclinicalgenetransferstateoftheart AT jimenezveronica clinibookclinicalgenetransferstateoftheart AT kallechristofvon clinibookclinicalgenetransferstateoftheart AT kangjagjeet clinibookclinicalgenetransferstateoftheart AT kentalastair clinibookclinicalgenetransferstateoftheart AT khalailehabed clinibookclinicalgenetransferstateoftheart AT kichlerantoine clinibookclinicalgenetransferstateoftheart AT kingnancymp clinibookclinicalgenetransferstateoftheart AT klatzmanndavid clinibookclinicalgenetransferstateoftheart AT kochanekstefan clinibookclinicalgenetransferstateoftheart AT kolodkingaldror clinibookclinicalgenetransferstateoftheart AT kootaeyoung clinibookclinicalgenetransferstateoftheart AT kunichernikolai clinibookclinicalgenetransferstateoftheart AT lachmannkristina clinibookclinicalgenetransferstateoftheart AT laufsstephanie clinibookclinicalgenetransferstateoftheart AT lemairestephanie clinibookclinicalgenetransferstateoftheart AT lemoinefrancois clinibookclinicalgenetransferstateoftheart AT lindgoran clinibookclinicalgenetransferstateoftheart AT lindenmaierwerner clinibookclinicalgenetransferstateoftheart AT linderothbengt clinibookclinicalgenetransferstateoftheart AT lockmartin clinibookclinicalgenetransferstateoftheart AT lucastanja clinibookclinicalgenetransferstateoftheart AT luzzattolucio clinibookclinicalgenetransferstateoftheart AT mackelars clinibookclinicalgenetransferstateoftheart AT maetzigtobias clinibookclinicalgenetransferstateoftheart AT maldineythomas clinibookclinicalgenetransferstateoftheart AT malerbaalberto clinibookclinicalgenetransferstateoftheart AT mannchristopher clinibookclinicalgenetransferstateoftheart AT mariecorinne clinibookclinicalgenetransferstateoftheart AT marquesalvespaula clinibookclinicalgenetransferstateoftheart AT mertenottowilhelm clinibookclinicalgenetransferstateoftheart AT meyringwilhelm clinibookclinicalgenetransferstateoftheart AT mignetnathalie clinibookclinicalgenetransferstateoftheart AT mingozzifederico clinibookclinicalgenetransferstateoftheart AT mitrophanouskyriacos clinibookclinicalgenetransferstateoftheart AT modlichute clinibookclinicalgenetransferstateoftheart AT monfaredparisa clinibookclinicalgenetransferstateoftheart AT montinieugenio clinibookclinicalgenetransferstateoftheart AT moullierphilippe clinibookclinicalgenetransferstateoftheart AT naldiniluigi clinibookclinicalgenetransferstateoftheart AT nathwaniamitc clinibookclinicalgenetransferstateoftheart AT nienhuisarthurw clinibookclinicalgenetransferstateoftheart AT palfistephane clinibookclinicalgenetransferstateoftheart AT panetamos clinibookclinicalgenetransferstateoftheart AT peixotocristina clinibookclinicalgenetransferstateoftheart AT pohlsusanne clinibookclinicalgenetransferstateoftheart AT popplewelllinda clinibookclinicalgenetransferstateoftheart AT paquesfrederic clinibookclinicalgenetransferstateoftheart AT rajdeepak clinibookclinicalgenetransferstateoftheart AT ralphrscott clinibookclinicalgenetransferstateoftheart AT reissulrike clinibookclinicalgenetransferstateoftheart AT richardcyrille clinibookclinicalgenetransferstateoftheart AT rischmulleranja clinibookclinicalgenetransferstateoftheart AT rodriguesanaf clinibookclinicalgenetransferstateoftheart AT rosenzwajgmichelle clinibookclinicalgenetransferstateoftheart AT santosjorgem clinibookclinicalgenetransferstateoftheart AT schambachaxel clinibookclinicalgenetransferstateoftheart AT schaserthomas clinibookclinicalgenetransferstateoftheart AT schermandaniel clinibookclinicalgenetransferstateoftheart AT schleefmartin clinibookclinicalgenetransferstateoftheart AT schmeermarco clinibookclinicalgenetransferstateoftheart AT schmidtmanfred clinibookclinicalgenetransferstateoftheart AT schweizermatthias clinibookclinicalgenetransferstateoftheart AT schaferssonja clinibookclinicalgenetransferstateoftheart AT seigerake clinibookclinicalgenetransferstateoftheart AT simaodaniel clinibookclinicalgenetransferstateoftheart AT sixadrien clinibookclinicalgenetransferstateoftheart AT smithalexanderj clinibookclinicalgenetransferstateoftheart AT smithjulianne clinibookclinicalgenetransferstateoftheart AT snyderrichardo clinibookclinicalgenetransferstateoftheart AT sofiacoroadinhaana clinibookclinicalgenetransferstateoftheart AT sousamarcosfq clinibookclinicalgenetransferstateoftheart AT suerthjuliad clinibookclinicalgenetransferstateoftheart AT sundstromerik clinibookclinicalgenetransferstateoftheart AT tayebshay clinibookclinicalgenetransferstateoftheart AT thomasmichael clinibookclinicalgenetransferstateoftheart AT thomasvaslinveronique clinibookclinicalgenetransferstateoftheart AT tuddenhamedwardgd clinibookclinicalgenetransferstateoftheart AT vandendriesschethierry clinibookclinicalgenetransferstateoftheart AT verhoeyenels clinibookclinicalgenetransferstateoftheart AT vermainderm clinibookclinicalgenetransferstateoftheart AT vielthomas clinibookclinicalgenetransferstateoftheart AT waerzeggersyannic clinibookclinicalgenetransferstateoftheart AT wahlberglars clinibookclinicalgenetransferstateoftheart AT winkeleralexandra clinibookclinicalgenetransferstateoftheart AT wirthdagmar clinibookclinicalgenetransferstateoftheart AT ylaherttualaseppo clinibookclinicalgenetransferstateoftheart AT zacchignaserena clinibookclinicalgenetransferstateoftheart AT zamirgidi clinibookclinicalgenetransferstateoftheart |
status_str |
n |
ids_txt_mv |
(DE-B1597)634993 (OCoLC)834607434 |
carrierType_str_mv |
cr |
hierarchy_parent_title |
Title is part of eBook package: De Gruyter EDP Sciences Backlist eBook Package 2000-2013 |
is_hierarchy_title |
The CliniBook : Clinical gene transfer state of the art / |
container_title |
Title is part of eBook package: De Gruyter EDP Sciences Backlist eBook Package 2000-2013 |
author2_original_writing_str_mv |
noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField |
_version_ |
1806144149100953600 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>26314nam a22026775i 4500</leader><controlfield tag="001">9782842542375</controlfield><controlfield tag="003">DE-B1597</controlfield><controlfield tag="005">20221201113901.0</controlfield><controlfield tag="006">m|||||o||d||||||||</controlfield><controlfield tag="007">cr || ||||||||</controlfield><controlfield tag="008">221201t20122012fr fo d z eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9782842542375</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1051/978-2-84254-237-5</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-B1597)634993</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)834607434</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-B1597</subfield><subfield code="b">eng</subfield><subfield code="c">DE-B1597</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="a">fr</subfield><subfield code="c">FR</subfield></datafield><datafield tag="072" ind1=" " ind2="7"><subfield code="a">MED047000</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Cohen-Haguenauer, Odile, </subfield><subfield code="e">author.</subfield><subfield code="4">aut</subfield><subfield code="4">http://id.loc.gov/vocabulary/relators/aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The CliniBook :</subfield><subfield code="b">Clinical gene transfer state of the art /</subfield><subfield code="c">Odile Cohen-Haguenauer.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Les Ulis : </subfield><subfield code="b">EDP Sciences, </subfield><subfield code="c">[2012]</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">©2012</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (589 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="347" ind1=" " ind2=" "><subfield code="a">text file</subfield><subfield code="b">PDF</subfield><subfield code="2">rda</subfield></datafield><datafield tag="505" ind1="0" ind2="0"><subfield code="t">Frontmatter -- </subfield><subfield code="t">CliniGene Partners and Boards -- </subfield><subfield code="t">ACKNOWLEDGMENTS -- </subfield><subfield code="t">List of authors -- </subfield><subfield code="t">Contents -- </subfield><subfield code="t">INTRODUCTION -- </subfield><subfield code="t">In-1 Foreword -- </subfield><subfield code="t">In-2 Main achievements and prospects downstream of the CliniGene-NoE -- </subfield><subfield code="t">PART I: TECHNOLOGIES AND PRE-CLINICAL STUDIES -- </subfield><subfield code="t">TECHNOLOGIES - Highlights on AAV mediated gene transfer -- </subfield><subfield code="t">A1-1 Highlights on AAV mediated gene transfer: introduction -- </subfield><subfield code="t">A1-2 Preclinical studies of AAV gene therapy for inherited retinal dystrophies -- </subfield><subfield code="t">A1-3 AAV-mediated gene therapy for MPS VI -- </subfield><subfield code="t">A1-4 Microdystrophin and myostatin gene therapy for Duchenne muscular dystrophy using adeno-associated virus vectors -- </subfield><subfield code="t">A1-5 AAV gene therapy for cardiovascular disorders -- </subfield><subfield code="t">A1-6 AAV gene therapy for diabetes mellitus -- </subfield><subfield code="t">A1-7 Approaches to large scale production of AAV-vectors -- </subfield><subfield code="t">A1-8 Reference materials for the characterization of adeno-associated viral vectors -- </subfield><subfield code="t">TECHNOLOGIES - Retrovirus mediated gene transfer state-of-the-art -- </subfield><subfield code="t">A2-1 Highlights on retrovirus mediated gene transfer -- </subfield><subfield code="t">A2-2 Retroviral vector development: reducing genotoxicity of integrated DNA and creating virus-like particles for transient cell modification -- </subfield><subfield code="t">A2-3 Replication-competent y-retroviral vectors for tumor therapy -- </subfield><subfield code="t">A2-4 Modular retroviral producer cell lines -- </subfield><subfield code="t">TECHNOLOGIES - Highlights on lentivirus mediated gene transfer -- </subfield><subfield code="t">A3-1 Introduction -- </subfield><subfield code="t">A3-2 MicroRNAs detargeting technology in the context of CNS applications -- </subfield><subfield code="t">A3-3 Development of SIVsmmPBj vectors for gene transfer into myeloid cells -- </subfield><subfield code="t">A3-4 Insulated retrovirus vectors using novel synthetic genetic insulator elements to circumvent enhancer-mediated genotoxicity -- </subfield><subfield code="t">A3-5 Facing the challenges of downstream processing of lentiviral vectors -- </subfield><subfield code="t">A3-6 Restrictions and requirements for stable lentiviral vector production in HEK293 cells -- </subfield><subfield code="t">A3-7 Novel lentiviral vector pseudotypes for stable gene transfer into resting hematopoietic cells -- </subfield><subfield code="t">TECHNOLOGIES - Highlights on gene-modified cell therapy -- </subfield><subfield code="t">A4-1 Cell therapy Introduction -- </subfield><subfield code="t">A4-2 Ex-vivo expansion of human mesenchymal stem cells -- </subfield><subfield code="t">A4-3 Closed bag cultivation systems for the production of gene modified dendritic cells and MSC for clinical use -- </subfield><subfield code="t">A4-4 Genetically modified NK cells for cancer treatment: facts and visions -- </subfield><subfield code="t">A4-5 Regulatory T lymphocyte depletion for cancer immunotherapies -- </subfield><subfield code="t">A4-6 Gene therapy of Fanconi’s anaemia aplastic syndrome -- </subfield><subfield code="t">TECHNOLOGIES - Adenovirus mediated gene transfer: current developments -- </subfield><subfield code="t">A5-1 Overview on adenovirus vectors -- </subfield><subfield code="t">A5-2 Tumour barriers influencing adenovirus vector delivery and therapeutic efficacy -- </subfield><subfield code="t">A5-3 Tumor imaging with adenoviral vectors -- </subfield><subfield code="t">A5-4 Treatment of brain tumors with adenoviruses: preclinical development -- </subfield><subfield code="t">A5-5 Production and purification of Ad vectors: current status and future needs for adenovirus vector production -- </subfield><subfield code="t">TECHNOLOGIES - Non-viral based gene transfer: a new era -- </subfield><subfield code="t">A6-1 Non viral plasmid delivery and imaging of transgene expression A6-1 Non viral plasmid delivery and imaging of transgene expression -- </subfield><subfield code="t">A6-2 Overview of novel plasmid vectors and preclinical applications -- </subfield><subfield code="t">A6-3 Filling a gap: S/MAR-based replicating minicircles -- </subfield><subfield code="t">A6-4 Manufacturing and QC of plasmid based vectors -- </subfield><subfield code="t">A6-5 Sleeping Beauty transposon based gene therapy -- </subfield><subfield code="t">A6-6 Development of minicircle vectors -- </subfield><subfield code="t">A6-7 Exon skipping therapy for DMD using antisense oligomer technology -- </subfield><subfield code="t">TECHNOLOGIES - Highlights on emerging technologies, iPS induction and genetic stability -- </subfield><subfield code="t">A7-1 Induction of pluripotency from adult somatic cells: a review -- </subfield><subfield code="t">A7-2 Genetic modification of adult stem cells and induced pluripotent stem cells with emerging transposon technologies -- </subfield><subfield code="t">A7-3 Targeted genome engineering approaches based on rare-cutting endonucleases: a tentative summary -- </subfield><subfield code="t">A7-4 Targeted genome modifications with designer nucleases -- </subfield><subfield code="t">PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - Preclinical assessment tools -- </subfield><subfield code="t">B1-1 Preclinical assessment tools: imaging gene transfer to the brain -- </subfield><subfield code="t">B1-2 Persistent luminescence nanoparticles for in vivo imaging: characteristics and targeting -- </subfield><subfield code="t">B1-3 Ex-vivo evaluation of gene-transfer vectors: efficacy, tropism and safety -- </subfield><subfield code="t">PRE-CLINICAL STUDIES, BIOSAFETY AND ANIMAL MODELS - General biosafety: immune responses, immunotoxicity and genotoxicity -- </subfield><subfield code="t">B2-1 Assessing and taming unwanted immune responses induced by AAV gene transfer: current status, ongoing questions and future prospects -- </subfield><subfield code="t">B2-2 Predicting immune responses to viral vectors and transgenes in gene therapy and vaccination: the coming of systems biology -- </subfield><subfield code="t">B2-3 Biosafety analysis in preclinical and clinical studies -- </subfield><subfield code="t">PART II Clinical trials and regulatory issues -- </subfield><subfield code="t">CLINICAL TRIALS -- </subfield><subfield code="t">C1-1 A clinical trial of AAV-mediated gene therapy for Leber congenital amaurosis 2 -- </subfield><subfield code="t">C1-2 Gene therapy for X-linked adrenoleukodystrophy based on lentiviral correction of hematopoietic stem cells -- </subfield><subfield code="t">C1-3 Immune reconstitution after gene therapy for adenosine deaminase severe combined immunodeficiency (ADA-SCID) -- </subfield><subfield code="t">C1-4 Gene therapy in Alzheimer disease patients -- </subfield><subfield code="t">C1-5 Cardiovascular gene therapy trials -- </subfield><subfield code="t">C1-6 AAV-mediated gene therapy for haemophilia B -- </subfield><subfield code="t">C1-7 ProSavin®: a lentiviral vector approach for the treatment of Parkinson’s disease -- </subfield><subfield code="t">ETHICAL AND REGULATORY ISSUES -- </subfield><subfield code="t">C2-1 Ethics in translation from research to therapy -- </subfield><subfield code="t">C2-2 Centralised regulation of gene therapy in Europe -- </subfield><subfield code="t">C2-3 The necessity for data sharing towards advancement of clinical translation Building up sample IMPD* and substantiating master files -- </subfield><subfield code="t">INTEGRATION AND DISSEMINATION -- </subfield><subfield code="t">C3-1 European Union support to gene transfer and gene therapy -- </subfield><subfield code="t">C3-2 Database of clinical trials -- </subfield><subfield code="t">C3-3 CliniGene and ESGCT shared vision for gene therapy in Europe: past, present and future prospects -- </subfield><subfield code="t">AUTHOR INDEX</subfield></datafield><datafield tag="506" ind1="0" ind2=" "><subfield code="a">restricted access</subfield><subfield code="u">http://purl.org/coar/access_right/c_16ec</subfield><subfield code="f">online access with authorization</subfield><subfield code="2">star</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation.</subfield></datafield><datafield tag="538" ind1=" " ind2=" "><subfield code="a">Mode of access: Internet via World Wide Web.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">In English.</subfield></datafield><datafield tag="588" ind1="0" ind2=" "><subfield code="a">Description based on online resource; title from PDF title page (publisher's Web site, viewed 01. Dez 2022)</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Genetic transformation.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Laboratory Medicine.</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Aiuti, Alessandro, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ali, Robin R., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Alici, Evren, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Almqvist, Per, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Annunziata, Patrizia, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Anton, Martina, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Artus, Alexandre, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Athanasopoulos, Takis, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Aubourg, Patrick, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Auregan, Gwennaelle, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Auricchio, Alberto, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bandeira, Vanessa, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bartholomae, Cynthia C., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Baum, Christopher, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bayart, Émilie, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bednarski, Christien, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bellier, Bertrand, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Biasco, Luca, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bigey, Pascal, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Blouin, Véronique, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bode, Juergen, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bonvento, Gilles, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bosch, Fatima, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bougnères, Pierre, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brigida, Immacolata, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Broll, Sandra, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Buchholz, Christian J., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bureau, Michel-Francis, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Bárcia, Rita N., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Callejas, David, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Carina Silva, Ana, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Carrondo, Manuel J.T., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cartier, Nathalie, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cathomen, Toni, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cavazzana-Calvo, Marina, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chuah, Marinee K.L., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cichutek, Klaus, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cohen-Haguenauer, Odile, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Colin, Angélique, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cordova, Gonzalo, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Coroadinha, Ana Sofia, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cosset, François-Loïc, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cotugno, Gabriella, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cruz, Helder J.S, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cruz, Pedro E., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Darmon, Christophe, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Davidoff, Andrew M., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dickson, George, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dittmar, Kurt E.J., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Draghia-Akli, Ruxandra, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dufour, Noëlle, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Duros, Caroline, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Déglon, Nicole, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dürner, Lydia, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Eriksdotter-Jönhagen, Maria, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Escartin, Carole, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Escriou, Virginie, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Eyjolfsdottir, Helga, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Faideau, Mathilde, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fischer, Alain, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Foster, Helen, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Foster, Keith, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gahrton, Gösta, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Galla, Melanie, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Galy, Anne, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gama-Norton, Leonor, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Garritsen, Henk S.P., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Georgiadis, Anastasios, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Giacca, Mauro, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gilljam, Mari, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gänsbacher, Bernd, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hacein-Bey-Abina, Salima, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hantraye, Philippe, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Haskins, Mark, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hassig, Raymonde, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hauser, Hansjörg, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Heinz, Niels, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Händel, Eva-Maria, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ivics, Zoltán, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Izsvák, Zsuzsanna, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Jacobs, Andreas H., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Jarmin, Susan, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Jimenez, Veronica, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kalle, Christof von, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kang, Jagjeet, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kent, Alastair, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Khalaileh, Abed, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kichler, Antoine, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">King, Nancy M.P., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Klatzmann, David, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kochanek, Stefan, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kolodkin-Gal, Dror, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Koo, Taeyoung, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kunicher, Nikolai, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lachmann, Kristina, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Laufs, Stephanie, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lemaire, Stéphanie, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lemoine, François, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lind, Göran, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lindenmaier, Werner, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Linderoth, Bengt, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lock, Martin, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lucas, Tanja, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Luzzatto, Lucio, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Macke, Lars, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Maetzig, Tobias, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Maldiney, Thomas, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Malerba, Alberto, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mann, Christopher, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Marie, Corinne, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Marques Alves, Paula, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Merten, Otto-Wilhelm, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Meyring, Wilhelm, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mignet, Nathalie, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mingozzi, Federico, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mitrophanous, Kyriacos, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Modlich, Ute, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Monfared, Parisa, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Montini, Eugenio, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Moullier, Philippe, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Naldini, Luigi, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nathwani, Amit C., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nienhuis, Arthur W., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Palfi, Stéphane, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Panet, Amos, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Peixoto, Cristina, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pohl, Susanne, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Popplewell, Linda, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pâques, Frédéric, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Raj, Deepak, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ralph, R. Scott, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Reiss, Ulrike, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Richard, Cyrille, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rischmüller, Anja, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rodrigues, Ana F., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rosenzwajg, Michelle, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Santos, Jorge M., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schambach, Axel, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schaser, Thomas, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Scherman, Daniel, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schleef, Martin, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schmeer, Marco, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schmidt, Manfred, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schweizer, Matthias, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schäfers, Sonja, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Seiger, Åke, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Simão, Daniel, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Six, Adrien, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Smith, Alexander J, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Smith, Alexander J., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Smith, Julianne, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Snyder, Richard O., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sofia Coroadinha, Ana, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sousa, Marcos F.Q., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Suerth, Julia D., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sundström, Erik, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tayeb, Shay, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Thomas, Michael, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Thomas-Vaslin, Véronique, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tuddenham, Edward G.D., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">VandenDriessche, Thierry, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Verhoeyen, Els, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Verma, Inder M., </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Viel, Thomas, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Waerzeggers, Yannic, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wahlberg, Lars, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Winkeler, Alexandra, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wirth, Dagmar, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ylä-Herttuala, Seppo, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zacchigna, Serena, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zamir, Gidi, </subfield><subfield code="e">contributor.</subfield><subfield code="4">ctb</subfield><subfield code="4">https://id.loc.gov/vocabulary/relators/ctb</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Title is part of eBook package:</subfield><subfield code="d">De Gruyter</subfield><subfield code="t">EDP Sciences Backlist eBook Package 2000-2013</subfield><subfield code="z">9783111024110</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1051/978-2-84254-237-5</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.degruyter.com/isbn/9782842542375</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="3">Cover</subfield><subfield code="u">https://www.degruyter.com/document/cover/isbn/9782842542375/original</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">978-3-11-102411-0 EDP Sciences Backlist eBook Package 2000-2013</subfield><subfield code="c">2008</subfield><subfield code="d">2013</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_BACKALL</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_CL_MDPM</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_EBACKALL</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_EBKALL</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_ECL_MDPM</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_EEBKALL</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_ESTMALL</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_PPALL</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">EBA_STMALL</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV-deGruyter-alles</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">PDA12STME</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">PDA13ENGE</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">PDA18STMEE</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">PDA5EBK</subfield></datafield></record></collection> |