Contraceptive Risk : : The FDA, Depo-Provera, and the Politics of Experimental Medicine / / William Green.

• Superior document: Title is part of eBook package: De Gruyter New York University Press Complete eBook-Package 2017
• VerfasserIn: Green, William,
• Place / Publishing House: New York, NY : : New York University Press, , [2017]; ©2017
• Year of Publication: 2017
• Language: English
• Series: Biopolitics ; 12
• Physical Description: 1 online resource

The story of Depo-Provera joins the national struggle over the drug's FDA approval to the state legal issues raised by its contraceptive and criminal justice uses.Depo-Provera is known as an injectable hormonal birth control method, but few are familiar with its dark and complicated history. Depo-Provera was tested on women since the mid-1960s without their informed consent until it was FDA-approved in 1992, but never FDA-approved as chemical castration for male sex offenders.Contraceptive Risk is William Green's landmark study of Depo-Provera. Based on a fascinating combination of archival materials and interviews, the book is framed as three interconnected stories told by Judith Weisz, who chaired the FDA's Public Board of Inquiry on Depo-Provera, a scientific court; by Anne MacMurdo who brought a products liability suit against Upjohn, the drug's manufacturer, for the deleterious side effects she suffered from the drug's use; and by Roger Gauntlett, an Upjohn heir who, when he was convicted of sexual assault, refused to take a dose of his family's own medicine as a probation condition. Together these three stories of Depo-Provera's convoluted fifty year odyssey call for a paradigm shift in pharmaceutical drug development.Contraceptive Risk is a thoroughly researched and engrossing approach to the scientific, political and institutional forces involved in health law and policy, as well as the multifaceted politics of measuring risk.

Table of Contents

Frontmatter -- Contents -- Preface and acknowledgments -- Note to the reader -- Introduction. The odyssey of depo- provera -- 1. The Grady hospital study: the corruption of contraceptive research -- 2. The twenty- five-year fda approval controversy: cancer and the politics of acceptable risk -- 3. Contraceptive chaos: unapproved use and Upjohn v. Macmurdo -- 4. Marketing approval and litigation: osteoporosis and the realities of medical risk -- 5. Chemical castration: the johns hopkins clinic and people v. gauntlett -- Conclusion. Contraceptive drug risk failure, human dignity, and a duty to act -- Glossary of legal and medical terms -- Notes -- Index -- About the author