Eicosanoids in Invertebrate Signal Transduction Systems / / David W. Stanley.

• Superior document: Title is part of eBook package: De Gruyter Princeton Legacy Lib. eBook Package 1980-1999
• VerfasserIn: Stanley, David W.,
• MitwirkendeR: Howard, Ralph W.,
• Place / Publishing House: Princeton, NJ : : Princeton University Press, , [2014]; ©1999
• Year of Publication: 2014
• Edition: Core Textbook
• Language: English
• Series: Princeton Legacy Library ; 86
• Physical Description: 1 online resource (290 p.) :; 5 tables 2 line illus. 5 halftones 28 figures

This volume generates a new paradigm for researching and understanding the biological meaning of eicosanoids. Eicosanoid is a general term for oxygenated metabolites of certain polyunsaturated fatty acids. The compounds are extremely important in human biology, in which they are well understood. Their importance to humans, however, has tended to overshadow their broader biological significance. David Stanley seeks to change that in this book, providing a general sketch of the medical background on eicosanoids and then developing a detailed critical treatment of eicosanoid actions in invertebrates and some lower vertebrates.Stanley looks at the role of eicosanoids in, for example, invertebrate reproduction, immunity, and ion transport physiology. As he explains, eicosanoids also mediate important ecological interactions, particularly host-parasite interactions. Drawing on these physiological and ecological actions, the book develops a "biological paradigm," under which we understand that eicosanoids probably exert important actions in most, if not all, animals. Because eicosanoids mediate crucial events in the lives of animals, they are endowed with unusual explanatory power. Research designed to increase our understanding of eicosanoids has thus yielded and will continue to yield important new information about animal biology. In addition to representing a major advance in our understanding of eicosanoids in animals, this book serves as an unusually comprehensive and accessible introduction to eicosanoid research in general.Originally published in 1999.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Table of Contents

Frontmatter -- Contents -- Foreword -- Acknowledgments -- Chapter 1. Introduction: A Theory of the Biological Significance of Eicosanoids -- Chapter 2. Eicosanoid Structures and Biosynthesis 11 The Mammalian Model of Eicosanoid Biosynthesis -- Chapter 3. Polyunsaturated Fatty Acids -- Chapter 4. Eicosanoids in the Reproductive Biology of Invertebrates -- Chapter 5. Eicosanoids in Invertebrate Immunity -- Chapter 6. Eicosanoids in Invertebrate Ion Transport Physiology -- Chapter 7. Emerging Eicosanoid Actions -- Chapter 8. Eicosanoids Mediate Ecological Interactions -- Chapter 9. A Research Prospectus: Approaching the Frontiers -- Abbreviations Used in References -- References -- Taxonomic Index -- Subject Index