Protein Targeting and Translocation / / ed. by D. A. Phoenix.

• Superior document: Title is part of eBook package: De Gruyter Princeton Legacy Lib. eBook Package 1980-1999
• MitwirkendeR: Baker, A.,; Brink, Susanne,; Brodsky, Jeffrey L.,; Broome-Smith, Jenny K.,; Driessen, Arnold J. M.,; Hashemzadeh-Bonehit, Lida,; Hovius, Ruud,; Imamotol, Naoko,; Jacob, Jansen P.,; Kiefer, D.,; Kiel, J.A.K.W.,; Klei, I.J. van der,; Kruijff, B. de,; Kuhn, A.,; Machamer, C.E.,; Mant, Alexandra,; Marron, M.B.,; Matsuyama, S.,; Mitsopoulos, Costas,; Miyamoto, Yoichi,; Nouwen, N.,; Pinheirof, T.J.T.,; Qanbar, R.,; Robinson, Colin,; Salmond, G.P.C.,; Smith, S.G.J.,; Smyth, C.J.,; Thomas, J.D.,; Tokuda, H.,; Tommassen, J.,; Tugal, B.,; Veenhuis, M.,; Watts, A.,; Wharamf, S.D.,; Yoneda, Yoshihiro,
• HerausgeberIn: Phoenix, D. A.,
• Place / Publishing House: Princeton, NJ : : Princeton University Press, , [2014]; ©1999
• Year of Publication: 2014
• Edition: Core Textbook
• Language: English
• Series: Princeton Legacy Library ; 79
• Physical Description: 1 online resource (306 p.)

Protein targeting is a fast-moving field that has encompassed areas from biophysics to molecular biology to try to gain insight into how proteins are directed to their final functional location and how such macromolecules are able to cross semi-permeable membrane barriers during their journey. This...

Table of Contents

• Frontmatter
• Contents
• Preface
• Abbreviations
• Membrane interactions
• Biophysics of the membrane interface and its involvement in protein targeting and translocation
• Amphiphilic α-helices and lipid interactions
• Signal sequences: initiators of protein translocation
• Determinants of membrane protein topology and membrane anchoring
• Insertion of single- and multispanning proteins into the bacterial cytoplasmic membrane
• Prokaryotic protein translocation
• Protein traffic from the cytosol to the outer membrane of Escherichia coli
• sec-dependent prokaryotic protein secretion
• Targeting and assembly of fimbriae
• Targeting to and translocation across the endoplasmic reticulum membrane
• Protein localization to the endoplasmic reticulum and Golgi complex
• Import and export of proteins at the nucleus
• Mitochondrial targeting and import
• Translocation of proteins into and across the thylakoid membrane
• Principles of peroxisomal protein sorting and assembly
• Targeting of glyoxysomal proteins
• Subject index