Homology, Genes, and Evolutionary Innovation / / Günter P. Wagner.

Homology-a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird's wing-is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what ho...

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Superior document:Title is part of eBook package: De Gruyter Princeton University Press Complete eBook-Package 2014-2015
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Place / Publishing House:Princeton, NJ : : Princeton University Press, , [2014]
©2014
Year of Publication:2014
Edition:Course Book
Language:English
Online Access:
Physical Description:1 online resource (496 p.) :; 25 halftones. 105 line illus. 4 tables.
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100 1 |a Wagner, Günter P.,   |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
245 1 0 |a Homology, Genes, and Evolutionary Innovation /  |c Günter P. Wagner. 
250 |a Course Book 
264 1 |a Princeton, NJ :   |b Princeton University Press,   |c [2014] 
264 4 |c ©2014 
300 |a 1 online resource (496 p.) :  |b 25 halftones. 105 line illus. 4 tables. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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505 0 0 |t Frontmatter --   |t Contents --   |t Preface --   |t Introduction: What This Book Aims to Do and What It Is Not --   |t Part I. Concepts and Mechanisms --   |t Part II. Paradigms and Research Programs --   |t References --   |t Index 
506 0 |a restricted access  |u http://purl.org/coar/access_right/c_16ec  |f online access with authorization  |2 star 
520 |a Homology-a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird's wing-is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution.Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks-that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers.The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity. 
530 |a Issued also in print. 
538 |a Mode of access: Internet via World Wide Web. 
546 |a In English. 
588 0 |a Description based on online resource; title from PDF title page (publisher's Web site, viewed 30. Aug 2021) 
650 0 |a Developmental genetics. 
650 0 |a Evolution (Biology). 
650 0 |a Genetic regulation. 
650 7 |a SCIENCE / Life Sciences / Evolution.  |2 bisacsh 
653 |a adaptation. 
653 |a amniotes. 
653 |a angiosperms. 
653 |a autopodium. 
653 |a biological diversity. 
653 |a body parts. 
653 |a body plans. 
653 |a breasts. 
653 |a canalization. 
653 |a cell fate. 
653 |a cell type identity. 
653 |a cell types. 
653 |a cell typogenesis. 
653 |a cells. 
653 |a character identity network. 
653 |a character identity. 
653 |a character origination. 
653 |a character states. 
653 |a characters. 
653 |a cis-regulatory elements. 
653 |a class. 
653 |a common ancestor. 
653 |a common ancestry. 
653 |a cryptic genetic variation. 
653 |a development. 
653 |a developmental biology. 
653 |a developmental evolution. 
653 |a developmental genetics. 
653 |a developmental mechanisms. 
653 |a developmental pathways. 
653 |a developmental types. 
653 |a developmental variation. 
653 |a devo-evo research. 
653 |a digit identity. 
653 |a digit loss. 
653 |a digits. 
653 |a embryonic stem cells. 
653 |a evolution. 
653 |a evolutionary biology. 
653 |a evolutionary developmental biology. 
653 |a evolutionary novelties. 
653 |a feathers. 
653 |a fins. 
653 |a finЬimb transition. 
653 |a flower development. 
653 |a flower organ identity. 
653 |a flower organs. 
653 |a flowers. 
653 |a functional specialization. 
653 |a functionalism. 
653 |a gene duplication. 
653 |a gene expression. 
653 |a gene regulatory networks. 
653 |a genes. 
653 |a genetics. 
653 |a hair. 
653 |a hierarchical homology. 
653 |a homeotic genes. 
653 |a homologous genes. 
653 |a homologs. 
653 |a homology. 
653 |a individuals. 
653 |a innovation. 
653 |a limbs. 
653 |a metaphysics. 
653 |a modularity. 
653 |a molecular genetics. 
653 |a molecular structuralism. 
653 |a morphological characters. 
653 |a morphological variation. 
653 |a natural kinds. 
653 |a natural selection. 
653 |a novel characters. 
653 |a paired fins. 
653 |a pentadactyl limb. 
653 |a perianth. 
653 |a phenotypic diversity. 
653 |a phenotypic evolution. 
653 |a philosophy. 
653 |a population biology. 
653 |a positional information. 
653 |a robustness. 
653 |a scales. 
653 |a science. 
653 |a serial homology. 
653 |a signaling centers. 
653 |a skin appendages. 
653 |a skin derivatives. 
653 |a skin. 
653 |a structuralism. 
653 |a tetrapod hand. 
653 |a tetrapod limbs. 
653 |a transcription factor proteins. 
653 |a transcription factors. 
653 |a transcriptional regulation. 
653 |a transposable elements. 
653 |a typology. 
653 |a variational structuralism. 
653 |a vertebrates. 
773 0 8 |i Title is part of eBook package:  |d De Gruyter  |t Princeton University Press Complete eBook-Package 2014-2015  |z 9783110665925 
776 0 |c print  |z 9780691156460 
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