Selling Science : : Polio and the Promise of Gamma Globulin / / Stephen E. Mawdsley.

Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephe...

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Superior document:Title is part of eBook package: De Gruyter Rutgers University Press Complete eBook-Package 2016
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Place / Publishing House:New Brunswick, NJ : : Rutgers University Press, , [2016]
©2016
Year of Publication:2016
Language:English
Series:Critical Issues in Health and Medicine
Online Access:
Physical Description:1 online resource (231 p.) :; 14 photographs, 3 maps, 4 figures
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Other title:Frontmatter --
Contents --
Illustrations --
Acknowledgments --
Abbreviations --
Introduction --
Chapter 1. Forging Momentum --
Chapter 2. Building Consent for a Clinical Trial --
Chapter 3. Marketing and Mobilization --
Chapter 4. The Pilot Study --
Chapter 5. Operation Marbles and Lollipops --
Chapter 6. The National Experiment --
Notes --
Bibliography --
Index
Summary:Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephen E. Mawdsley recounts the untold story of the first large clinical trial to control polio using healthy children—55,000 healthy children—revealing how this long-forgotten incident cleared the path for Salk’s later trial. Mawdsley describes how, in the early 1950s, Dr. William Hammon and the National Foundation for Infantile Paralysis launched a pioneering medical experiment on a previously untried scale. Conducted on over 55,000 healthy children in Texas, Utah, Iowa, and Nebraska, this landmark study assessed the safety and effectiveness of a blood component, gamma globulin, to prevent paralytic polio. The value of the proposed experiment was questioned by many prominent health professionals as it harbored potential health risks, but as Mawdsley points out, compromise and coercion moved it forward. And though the trial returned dubious results, it was presented to the public as a triumph and used to justify a federally sanctioned mass immunization study on thousands of families between 1953 and 1954. Indeed, the concept, conduct, and outcome of the GG study were sold to health professionals, medical researchers, and the public at each stage. At a time when most Americans trusted scientists, their mutual encounter under the auspices of conquering disease was shaped by politics, marketing, and at times, deception. Drawing on oral history interviews, medical journals, newspapers, meeting minutes, and private institutional records, Selling Science sheds light on the ethics of scientific conduct, and on the power of marketing to shape public opinion about medical experimentation.
Format:Mode of access: Internet via World Wide Web.
ISBN:9780813574417
9783110666144
DOI:10.36019/9780813574417
Access:restricted access
Hierarchical level:Monograph
Statement of Responsibility: Stephen E. Mawdsley.