How We Age : : The Science of Longevity / / Coleen T. Murphy.

• VerfasserIn: Murphy, Coleen T.,
• Place / Publishing House: Princeton, NJ : : Princeton University Press, , [2023]; 2023
• Year of Publication: 2023
• Language: English
• Physical Description: 1 online resource (464 p.) :; 7 b/w illus.

How recent breakthroughs in longevity research offer clues about human agingAll of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar...

Table of Contents

• Frontmatter
• Contents
• Acknowledgments
• Abbreviations
• Introduction
• 1 Ethics and Economics of Longevity: is it right to study aging?
• 2 Why Do We Age?
• 3 Studying the Genetics of Human Longevity: centenarians and what we can learn from them
• 4 Long-Lived Species and Longevity Mutants of Model Organisms
• 5 What Is Aging (and How Can We Measure It)? biomarkers of aging and "quality of life" metrics
• 6 Insulin Signaling, FOXO Targets, and the Regulation of Longevity and Reproduction
• 7 Dietary Restriction: nutrient and genetic regulation of longevity and reproduction
• 8 Taking out the Trash: molecular homeostasis in the regulation of longevity
• 9 Powering Longevity: mitochondria's role in aging and longevity
• 10 Dracula and Wolverine: how DNA repair and cell replacement can help us live long
• 11 Use It or Lose It: reproductive aging, the germline, and longevity
• 12 Sex, Flies (and Worms), and Videotape: the battle of the sexes
• 13 I See Dead Flies: neurons and sensory regulation of longevity
• 14 Don't You Forget about Me: what we are learning about cognitive aging and how to slow it
• 15 Lamarck's Revenge? Transgenerational inheritance, the "molecular clock," and the epigenetic regulation of longevity
• 16 Gut Feelings: the microbiome and aging
• 17 Long Life in a Pill? the future of longevity: from bench to biotech
• Notes
• Index
• A NOTE ON THE TYPE