Immunology and Evolution of Infectious Disease /

Immunology and Evolution of Infectious Disease / / Steven A. Frank.

From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecolo...

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Bibliographic Details
Superior document:Title is part of eBook package: De Gruyter Princeton University Press eBook-Package Backlist 2000-2013
VerfasserIn:
Frank, Steven A.,
Place / Publishing House:Princeton, NJ : : Princeton University Press, , [2020]
©2002
Year of Publication:2020
Language:English
Online Access:
Physical Description:1 online resource (360 p.) :; 40 line illus.
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Table of Contents:
  • Frontmatter
  • Contents
  • Acknowledgments
  • 1. Introduction
  • PART I. BACKGROUND
  • 2. Vertebrate Immunity
  • 3. Benefits of Antigenic Variation
  • PART II. MOLECULAR PROCESSES
  • 4. Specificity and Cross-Reactivity
  • 5. Generative Mechanisms
  • PART III. INDIVIDUAL INTERACTIONS
  • 6. Immunodominance within Hosts
  • 7. Parasite Escape within Hosts
  • PART IV. POPULATION CONSEQUENCES
  • 8. Genetic Variability of Hosts
  • 9. Immunological Variability of Hosts
  • 10. Genetic Structure of Parasite Populations
  • 11. Classifications by Antigenicity and Phylogeny
  • 12. Experimental Evolution: Foot-and-Mouth Disease Virus
  • 13. Experimental Evolution: Influenza
  • 14. Experimental Evolution: CTL Escape
  • 15. Measuring Selection with Population Samples
  • 16. Recap of Some Interesting Problems
  • References
  • Author Index
  • Subject Index

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