The Molecular Switch : : Signaling and Allostery /

The Molecular Switch : : Signaling and Allostery / / Rob Phillips.

A signature feature of living organisms is their ability to carry out purposeful actions by taking stock of the world around them. To that end, cells have an arsenal of signaling molecules linked together in signaling pathways, which switch between inactive and active conformations. The Molecular Sw...

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Bibliographic Details
Superior document:Title is part of eBook package: De Gruyter EBOOK PACKAGE COMPLETE 2020 English
VerfasserIn:
Phillips, Rob,
Place / Publishing House:Princeton, NJ : : Princeton University Press, , [2020]
©2020
Year of Publication:2020
Language:English
Online Access:
Physical Description:1 online resource (440 p.) :; 351 color illus.
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Table of Contents:
  • Frontmatter
  • CONTENTS
  • PREFACE
  • PART I. THE MAKING OF MOLECULAR SWITCHES
  • 1. IT’S AN ALLOSTERIC WORLD
  • 2. THE ALLOSTERICIAN’S TOOLKIT
  • PART II. THE LONG REACH OF ALLOSTERY
  • 3. SIGNALING AT THE CELL MEMBRANE: ION CHANNELS
  • 4. HOW BACTERIA NAVIGATE THE WORLD AROUND THEM
  • 5. THE WONDERFUL WORLD OF G PROTEINS AND G PROTEIN–COUPLED RECEPTORS
  • 6. DYNAMICS OF MWC MOLECULES: ENZYME ACTION AND ALLOSTERY
  • 7. HEMOGLOBIN, NATURE’S HONORARY ENZYME
  • 8. HOW CELLS DECIDE WHAT TO BE: SIGNALING AND GENE REGULATION
  • 9. BUILDING LOGIC FROM ALLOSTERY
  • 10. DNA PACKING AND ACCESS: THE PHYSICS OF COMBINATORIAL CONTROL
  • PART III. BEYOND ALLOSTERY
  • 11. ALLOSTERY EXTENDED
  • 12. MAXWELL DEMONS, PROOFREADING, AND ALLOSTERY
  • 13. A FAREWELL TO ALLOSTERY
  • INDEX

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