The Cheating Cell : : How Evolution Helps Us Understand and Treat Cancer / / Athena Aktipis.
A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don't necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell...
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| Superior document: | Title is part of eBook package: De Gruyter EBOOK PACKAGE COMPLETE 2020 English |
|---|---|
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| Place / Publishing House: | Princeton, NJ : : Princeton University Press, , [2020] ©2019 |
| Year of Publication: | 2020 |
| Language: | English |
| Online Access: | |
| Physical Description: | 1 online resource (256 p.) :; 19 b/w illus. |
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| LEADER | 06879nam a22014535i 4500 | ||
|---|---|---|---|
| 001 | 9780691186085 | ||
| 003 | DE-B1597 | ||
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| 020 | |a 9780691186085 | ||
| 024 | 7 | |a 10.1515/9780691186085 |2 doi | |
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| 035 | |a (OCoLC)1135668643 | ||
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| 044 | |a nju |c US-NJ | ||
| 072 | 7 | |a MED062000 |2 bisacsh | |
| 100 | 1 | |a Aktipis, Athena, |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 4 | |a The Cheating Cell : |b How Evolution Helps Us Understand and Treat Cancer / |c Athena Aktipis. |
| 264 | 1 | |a Princeton, NJ : |b Princeton University Press, |c [2020] | |
| 264 | 4 | |c ©2019 | |
| 300 | |a 1 online resource (256 p.) : |b 19 b/w illus. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
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| 505 | 0 | 0 | |t Frontmatter -- |t CONTENTS -- |t Acknowledgments -- |t 1. Introduction: Evolution in the Flesh -- |t 2. Why Does Cancer Evolve? -- |t 3. Cheating in Multicellular Cooperation -- |t 4. Cancer from Womb to Tomb -- |t 5. Cancer across the Tree of Life -- |t 6. The Hidden World of Cancer Cells -- |t 7. How to Control Cancer -- |t Notes -- |t Bibliography -- |t Index |
| 506 | 0 | |a restricted access |u http://purl.org/coar/access_right/c_16ec |f online access with authorization |2 star | |
| 520 | |a A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don't necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer's evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer's ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn't mean we should give up on treating cancer-in fact evolutionary approaches offer new and promising options for the disease's prevention and treatments that aim at long-term management rather than simple eradication. Looking across species-from sponges and cacti to dogs and elephants-we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future-and that we cannot win a war against evolution-treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer's fundamental nature and our relationship to it. | ||
| 530 | |a Issued also in print. | ||
| 538 | |a Mode of access: Internet via World Wide Web. | ||
| 546 | |a In English. | ||
| 588 | 0 | |a Description based on online resource; title from PDF title page (publisher's Web site, viewed 30. Aug 2021) | |
| 650 | 7 | |a MEDICAL / Oncology. |2 bisacsh | |
| 653 | |a Adaptive Oncogenesis. | ||
| 653 | |a Azra Raza. | ||
| 653 | |a Cancer the Evolutionary Legacy. | ||
| 653 | |a Emperor of All Maladies. | ||
| 653 | |a James DeGregori. | ||
| 653 | |a Kat Arney. | ||
| 653 | |a Mel Greaves. | ||
| 653 | |a Richard Dawkins. | ||
| 653 | |a Selfish Monsters. | ||
| 653 | |a Siddhartha Mukherjee. | ||
| 653 | |a Tazmanian devil. | ||
| 653 | |a The First Cell. | ||
| 653 | |a The Selfish Gene. | ||
| 653 | |a adaptive therapy. | ||
| 653 | |a battle. | ||
| 653 | |a beat. | ||
| 653 | |a benign. | ||
| 653 | |a breast cancer. | ||
| 653 | |a cactus cancer. | ||
| 653 | |a cancer transmission. | ||
| 653 | |a cellular. | ||
| 653 | |a cheater. | ||
| 653 | |a clinical trial. | ||
| 653 | |a conflict. | ||
| 653 | |a containment. | ||
| 653 | |a cooperation theory. | ||
| 653 | |a doctor. | ||
| 653 | |a ecosystem. | ||
| 653 | |a fight. | ||
| 653 | |a free rider. | ||
| 653 | |a genomic. | ||
| 653 | |a geriatric. | ||
| 653 | |a immunity. | ||
| 653 | |a immunology. | ||
| 653 | |a immunotherapy. | ||
| 653 | |a lung cancer. | ||
| 653 | |a malignant. | ||
| 653 | |a maternal. | ||
| 653 | |a medical. | ||
| 653 | |a medicine. | ||
| 653 | |a metastasis. | ||
| 653 | |a metastasize. | ||
| 653 | |a microbial mediators. | ||
| 653 | |a multicellularity. | ||
| 653 | |a natural selection. | ||
| 653 | |a oncologist. | ||
| 653 | |a oncology. | ||
| 653 | |a paternal. | ||
| 653 | |a physician. | ||
| 653 | |a prostate cancer. | ||
| 653 | |a public health. | ||
| 653 | |a radiologist. | ||
| 653 | |a radiology. | ||
| 653 | |a regulator. | ||
| 653 | |a resistance. | ||
| 653 | |a thoracic. | ||
| 653 | |a transmissible cancer. | ||
| 653 | |a tree of life. | ||
| 653 | |a trophoblast. | ||
| 653 | |a tumor microenvironment. | ||
| 653 | |a wound healing. | ||
| 773 | 0 | 8 | |i Title is part of eBook package: |d De Gruyter |t EBOOK PACKAGE COMPLETE 2020 English |z 9783110704716 |
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| 773 | 0 | 8 | |i Title is part of eBook package: |d De Gruyter |t Princeton University Press Complete eBook-Package 2019 |z 9783110663365 |
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| 856 | 4 | 0 | |u https://doi.org/10.1515/9780691186085?locatt=mode:legacy |
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| 912 | |a 978-3-11-070471-6 EBOOK PACKAGE COMPLETE 2020 English |b 2020 | ||
| 912 | |a 978-3-11-070480-8 EBOOK PACKAGE Medicine and Life Sciences 2020 English |b 2020 | ||
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