First in Fly : : ‹i›Drosophila‹/i› Research and Biological Discovery / / Stephanie Elizabeth Mohr.
A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila’s importance as a research organism began with its short life cycle, ability to reproduce in large numbers,...
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Superior document: | Title is part of eBook package: De Gruyter Harvard University Press Complete eBook-Package 2018 |
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Place / Publishing House: | Cambridge, MA : : Harvard University Press, , [2018] ©2018 |
Year of Publication: | 2018 |
Language: | English |
Online Access: | |
Physical Description: | 1 online resource (270 p.) :; 21 line illustrations, 1 table |
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001 | 9780674984721 | ||
003 | DE-B1597 | ||
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024 | 7 | |a 10.4159/9780674984721 |2 doi | |
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035 | |a (OCoLC)1054879738 | ||
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041 | 0 | |a eng | |
044 | |a mau |c US-MA | ||
072 | 7 | |a SCI029000 |2 bisacsh | |
100 | 1 | |a Mohr, Stephanie Elizabeth, |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
245 | 1 | 0 | |a First in Fly : |b ‹i›Drosophila‹/i› Research and Biological Discovery / |c Stephanie Elizabeth Mohr. |
264 | 1 | |a Cambridge, MA : |b Harvard University Press, |c [2018] | |
264 | 4 | |c ©2018 | |
300 | |a 1 online resource (270 p.) : |b 21 line illustrations, 1 table | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
347 | |a text file |b PDF |2 rda | ||
505 | 0 | 0 | |t Frontmatter -- |t Contents -- |t Preface -- |t Introduction -- |t MAPS -- |t CHANGE -- |t COMMUNICATION -- |t SIZE -- |t DIRECTION -- |t DIFFERENCE -- |t DEFENSES -- |t BEHAVIOR -- |t COORDINATION -- |t CONTINUITY -- |t Epilogue -- |t APPENDIX A. How to Make a Flytrap -- |t APPENDIX B: Comparable Organs in Humans and Flies -- |t APPENDIX C: Selected Genetic Screens Performed in Drosophila -- |t Recommended Reading -- |t Abbreviations -- |t References -- |t Acknowledgments -- |t Index |
506 | 0 | |a restricted access |u http://purl.org/coar/access_right/c_16ec |f online access with authorization |2 star | |
520 | |a A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila’s importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these “first in fly” findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease. | ||
538 | |a Mode of access: Internet via World Wide Web. | ||
546 | |a In English. | ||
588 | 0 | |a Description based on online resource; title from PDF title page (publisher's Web site, viewed 24. Aug 2021) | |
650 | 0 | |a Animal models in research. | |
650 | 0 | |a Drosophila melanogaster |x Genetics. | |
650 | 0 | |a Drosophila melanogaster |x Physiology. | |
650 | 7 | |a SCIENCE / Life Sciences / Genetics & Genomics. |2 bisacsh | |
773 | 0 | 8 | |i Title is part of eBook package: |d De Gruyter |t Harvard University Press Complete eBook-Package 2018 |z 9783110606621 |
856 | 4 | 0 | |u https://doi.org/10.4159/9780674984721 |
856 | 4 | 0 | |u https://www.degruyter.com/isbn/9780674984721 |
856 | 4 | 2 | |3 Cover |u https://www.degruyter.com/cover/covers/9780674984721.jpg |
912 | |a 978-3-11-060662-1 Harvard University Press Complete eBook-Package 2018 |b 2018 | ||
912 | |a GBV-deGruyter-alles |