The Variation and Adaptive Expression of Antibodies / / George P. Smith.

During the past ten years, several theories have been proposed on the origin of the diversity of antibodies. George P. Smith presents a critical study of these theories in this detailed treatment of immunological problems from the point of view of molecular genetics. Mr. Smith uses a new and simplif...

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Bibliographic Details
Superior document:Title is part of eBook package: De Gruyter HUP e-dition: Complete eBook Package
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Place / Publishing House:Cambridge, MA : : Harvard University Press, , [2013]
©1973
Year of Publication:2013
Edition:Reprint 2014
Language:English
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Physical Description:1 online resource (219 p.)
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Table of Contents:
  • Frontmatter
  • Preface
  • Contents
  • Tables and Figures
  • Chapter 1. Introduction to the Immune Response
  • Chapter 2. The Basic Structure of Immunoglobulins
  • Chapter 3. Reconstructing Protein Evolution
  • Chapter 4. The Evolution of C Regions
  • Chapter 5. Theories of Antibody Diversity
  • Chapter 6. The Evolution of V Regions: The Case for the Germline Theory
  • Chapter 7. Species Specificity and Allotypes in V Regions: Evidence against the Germline Theory
  • Chapter 8. The Clonal Selection Theory
  • Chapter 9. The Joining of V and C Regions: Theories of Cell Commitment
  • Appendixes. References. Index
  • References
  • Index