Mind Thief : : The Story of Alzheimer's / / Han Yu.

• Superior document: Title is part of eBook package: De Gruyter Columbia University Press Complete eBook-Package 2021
• VerfasserIn: Yu, Han,
• Place / Publishing House: New York, NY : : Columbia University Press, , [2021]; ©2021
• Year of Publication: 2021
• Language: English
• Physical Description: 1 online resource :; 8 figures, 1 table

Alzheimer’s disease, a haunting and harrowing ailment, is one of the world’s most common causes of death. Alzheimer’s lingers for years, with patients’ outward appearance unaffected while their cognitive functions fade away. Patients lose the ability to work and live independently, to remember and recognize. There is still no proven way to treat Alzheimer’s because its causes remain unknown.Mind Thief is a comprehensive and engaging history of Alzheimer’s that demystifies efforts to understand the disease. Beginning with the discovery of “presenile dementia” in the early twentieth century, Han Yu examines over a century of research and controversy. She presents the leading hypotheses for what causes Alzheimer’s; discusses each hypothesis’s tangled origins, merits, and gaps; and details their successes and failures. Yu synthesizes a vast amount of medical literature, historical studies, and media interviews, telling the gripping stories of researchers’ struggles while situating science in its historical, social, and cultural contexts. Her chronicling of the trajectory of Alzheimer’s research deftly balances rich scientific detail with attention to the wider implications. In narrating the attempts to find a treatment, Yu also offers a critical account of research and drug development and a consideration of the philosophy of aging. Wide-ranging and accessible, Mind Thief is an important book for all readers interested in the challenge of Alzheimer’s.

Table of Contents

Frontmatter -- CONTENTS -- Preface -- Acknowledgments -- 1. Lost Wives -- 2. Cursed Inheritance -- 3. Learning to Walk -- 4. Searching for the Alzheimer’s Gene -- 5. Late-Onset Alzheimer’s -- 6. The Paradigm -- 7. Eli Lilly and Mice -- 8. Inhibitors That Can’t Inhibit -- 9. Poison or Cure: An Alzheimer’s Vaccine -- 10. Eli Lilly’s Three Expeditions -- 11. Taoism and Tau Mice -- 12. Apples, Oysters, and Underdogs -- 13. Type 3 Diabetes -- 14. Ketones: The Brain Fuel -- 15. Insulin Fixes -- 16. Bacteria in the Brain -- 17. Eat Your Vegetables (and Berries) -- 18. Blood, Heart, and Brain -- 19. A Missed Opportunity -- 20. Paradigm Shift(?) -- 21. An Enriched Life -- Epilogue -- Notes -- Bibliography -- Index