The Quest for the Cure : : The Science and Stories Behind the Next Generation of Medicines / / Brent Stockwell.
After more than fifty years of blockbuster drug development, skeptics are beginning to fear we are reaching the end of drug discovery to combat major diseases. In this engaging book, Brent R. Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and...
Saved in:
Superior document: | Title is part of eBook package: De Gruyter Columbia University Press eBook-Package Backlist 2000-2013 |
---|---|
VerfasserIn: | |
Place / Publishing House: | New York, NY : : Columbia University Press, , [2011] ©2011 |
Year of Publication: | 2011 |
Language: | English |
Online Access: | |
Physical Description: | 1 online resource (284 p.) :; 4 color illus., 18 line drawings |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Table of Contents:
- Frontmatter
- Contents
- List of Illustrations
- Preface
- Acknowledgments
- Abbreviations
- Part One. The Vanishing Cures
- 1. The Drug Discovery Crisis
- 2. A New Science of Molecules
- 3. The Birth of the First Cancer Drugs
- 4. A New Company Creating Drug Combinations
- 5. The Undruggable RAS Protein
- 6.The Druggable Genome
- Part Two. The Path to the Next Generation of Medicines
- 7. Peering Inside Proteins
- 8. The Nature of Interactions Between Proteins
- 9. From Protein- Protein Interactions to Personalized Medicines
- 10. A Revolution in Peptide Synthesis
- 11. A Vast Array of Drug Candidates
- 12. Moving Outside the Small Molecule Box
- 13. Accelerating the Arrival of Next- Generation Drugs
- Notes
- Glossary
- Index