Organic synthesis : the disconnection approach / / Stuart Warren and Paul Wyatt.
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| Year of Publication: | 2008 |
| Edition: | 2nd ed. |
| Language: | English |
| Online Access: | |
| Physical Description: | viii, 329 p. :; ill. |
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Table of Contents:
- The disconnection approach
- Basic principles : synthons and reagents synthesis of aromatic compounds
- Strategy I : the order of events
- One-group C-X disconnections
- Strategy II : chemoselectivity
- Two-group C-X disconnections
- Strategy III : reversal of polarity, cyclisations, summary of strategy
- Amine synthesis
- Strategy IV : protecting groups
- One group C-C disconnections I : alcohols
- General strategy A : choosing a disconnection
- Strategy V : stereoselectivity A
- One group C-C disconnections II : carbonyl compounds
- Strategy VI : regioselectivity
- Alkene synthesis
- Strategy VII : use of acetylenes (alkines)
- Two-group C-C disconnections I : Diels-Alder reactions
- Strategy VIII : introduction to carbonyl condensations
- Two-group C-C disconnections II : 1,3-difunctionalised compounds
- Strategy IX : control in carbonyl condensations
- Two-group C-C disconnections : 1,5-difunctionalised compounds
- Strategy X : aliphatic nitro compounds in synthesis
- Two-group disconnections IV : 1,2-difunctionalised compounds
- Strategy XI : radical reactions in synthesis
- Two-group disconnection V : 1,4-difunctionalised compounds
- Strategy XII : reconnection
- Two-group C-C disconnections VI : 1,6-diCarbonyl compounds
- General strategy B : strategy of carbonyl disconnections
- Strategy XIII : introduction to ring synthesis : saturated heterocycles
- Three-membered rings
- Strategy XIV : rearrangements in synthesis
- Four-membered rings : photochemistry in synthesis
- Strategy XV : the use of ketenes in synthesis
- Five-membered rings
- Strategy XVI : pericyclic reactions in synthesis : special methods for five-membered rings
- Six-membered rings
- General strategy C : strategy of ring synthesis
- Strategy XVII : stereoselectivity B
- Aromatic heterocycles
- General strategy D : advanced strategy.