Chiral drugs : chemistry and biological action / / edited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng.

"This book overviews chiral drugs and their impact in the pharmaceutical industry. The chapters detail basics and trends in chiral drug discovery and development, as well as techniques / skills and trends of asymmetric synthesis. The first section introduces the general concept of chirality and...

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Year of Publication:2011
Language:English
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Physical Description:x, 456 p. :; ill.
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Table of Contents:
  • Machine generated contents note: Chapter 1. Overview of chirality and chiral drugs (Guo-Qiang Lin, Jiange Zhang and Jie-Fei Cheng).
  • Chapter 2. Chiral drugs through asymmetric synthesis (Guo-Quiang Lin and Xing-Wen Sun).
  • Chapter 3. Chiral drugs via biocatalytical approaches (Jianqiang Wang and Wenya Lu).
  • Chapter 4. Chiral resolution (Qi-Dong You).
  • Chapter 5. Fluorine-containing chiral drugs (Xiao-Long Qiu, Xuyi Yue and Feng-Ling Qing).
  • Chapter 6. Industrial application of chiral technologies (Hui-Ying (Harry) Li, Rui Liu, Carl Behrens, and Chao-Ying Ni).
  • Chapter 7. Computation modeling study on mechanism-of-action of chiral drugs (Deping Wang and Eric Gu).
  • Chapter 8. Pharmacology of chiral drugs (Yongge Liu and Xiao-Hui Gu).
  • Chapter 9. Pharmacokinetics of chiral drugs (Hanqing Dong, Xiaochuan Guo and Zengbiao Li).
  • Chapter 10. Toxicology of chiral drugs (Guang Yang and Hai-Zhi Bu).
  • Chapter 11. Representative chiral drugs (Jiangqin Sun, Dingguo Liu and Zhimin Wang).