Kinetics of enzyme action : essential principles for drug hunters / / Ross L. Stein.
"Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to simple, one-substrate enzyme reactions a...
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| Year of Publication: | 2011 |
| Language: | English |
| Online Access: | |
| Physical Description: | xii, 302 p. :; ill. |
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Table of Contents:
- Kinetics of single-substrate enzymatic reactions
- Kinetics of single-substrate enzymatic reactions : special topics
- Enzyme inhibition : the phenomenon and mechanistic analysis
- Kinetic mechanism of inhibition of one-substrate enzymatic reactions
- Tight-binding, slow-binding, and irreversible inhibitors
- Kinetics of two-substrate enzymatic reactions
- Kinetic mechanism of inhibition of two-substrate enzymatic reactions
- Allosteric modulation of enzyme-catalyzed reactions
- Kinetics-based probes of enzyme mechanisms.