Drug efficacy, safety, and biologics discovery : emerging technologies and tools / / [edited by] Sean Ekins, Jinghai J. Xu.

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Bibliographic Details
Superior document:Wiley series on technologies for the pharmaceutical industry
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TeilnehmendeR:
Year of Publication:2009
Language:English
Series:Wiley series on technologies for the pharmaceutical industry.
Online Access:
Physical Description:xvi, 408 p., [16] p. of plates :; ill. (some col.).
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Table of Contents:
  • Focus on the fundamentals : toward better therapeutic index prediction / Jinghai J. Xu and Li J. Yu
  • High-throughput protein-based technologies and computational models for drug development, efficacy, and toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, and Christopher W. Espelin
  • Cellular systems biology applied to preclinical safety testing : a case study of CellCiphr profiling / Lawrence Vernetti ... [et al.]
  • Systems pharmacology, biomarkers, and biomolecular networks / Aram S. Adourian ... [et al.]
  • Zebrafish models for human diseases and drug discovery / Hanbing Zhong, Ning-Ai Liu, and Shuo Lin
  • Toxicity pathways and models : mining for potential side effects / Sean Ekins and Josef Scheiber
  • Computational systems biology modeling of dosimetry and cellular response pathways / Qiang Zhang ... [et al.]
  • Stem cell technology for embryotoxicity, cardiotoxicity, and hepatotoxicity evaluation / Julio C. Davila ... [et al.]
  • Telemetry technology for preclinical drug discovery and development / Yi Yang
  • Nanotechnology to improve oral drug delivery / Mayank D. Bhavsar, Shardool Jain, and Mansoor M. Amiji
  • Functional glycomics and the future of glycomic drugs / Ram Sasisekharan and Karthik Viswanathan
  • Modeling efficacy and safety of engineered biologics / Jeffrey R. Chabot and Bruce Gomes
  • Regulation of gene expression by small, non-coding RNAS : practical applications / Roman Herrara and Eric Tien
  • Future perspectives of biological engineering in pharmaceutical research : the paradigm of modeling, mining, manipulation, and measurements / Jinghai J. Xu ... [et al.].