Foundations of comparative genomics / Arcady R. Mushegian.
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| Year of Publication: | 2007 |
| Language: | English |
| Online Access: | |
| Physical Description: | ix, 265 p. :; ill. |
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Table of Contents:
- The beginning of computational genomics
- Finding sequence similarities
- Homology: can we get it right?
- Getting ready for the era of comparative genomics: the importance of viruses
- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution
- The second fact of comparative genomics: functional convergence at the molecular level
- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches
- Prediction of function and reconstruction of metabolism: post-homology approaches
- Structural genomics: what does it tell us about life?
- How many protein families are there?
- Phylogenetic inference and the era of complete genomes
- Two stories about evolution
- Minimal and ancestral genomes
- Comparative genomics and systems biology.