Females are mosaics : : X inactivation and sex differences in disease / / Barbara R. Migeon.

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Bibliographic Details
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Place / Publishing House:Oxford : : Oxford University Press,, [2014]
2014
Year of Publication:2014
Edition:Second edition.
Language:English
Online Access:
Physical Description:1 online resource (328 pages) :; illustrations
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Table of Contents:
  • Sex differences in disease
  • Evolution of the human sex chromosomes and a portrait of the human X
  • X chromosome dosage compensation : an overview
  • The discovery of X chromosome inactivation
  • Experimental models for X inactivation studies
  • Theme 1 : the initial step : creating the active and inactive X
  • Theme 2 : subsequent steps : spreading and maintaining inactivation
  • Variations 1 : evolution of the X inactivation center
  • Variations 2 : stability of the inactive X
  • Variations 3 : choice of active X
  • The single active X
  • Mosaicism
  • Epimutations, chromatin disorders and sex differences in phenotype
  • Determinants of female phenotypes.