Females are mosaics : : X inactivation and sex differences in disease / / Barbara R. Migeon.
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Place / Publishing House: | Oxford : : Oxford University Press,, [2014] 2014 |
Year of Publication: | 2014 |
Edition: | Second edition. |
Language: | English |
Online Access: | |
Physical Description: | 1 online resource (328 pages) :; illustrations |
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Table of Contents:
- Sex differences in disease
- Evolution of the human sex chromosomes and a portrait of the human X
- X chromosome dosage compensation : an overview
- The discovery of X chromosome inactivation
- Experimental models for X inactivation studies
- Theme 1 : the initial step : creating the active and inactive X
- Theme 2 : subsequent steps : spreading and maintaining inactivation
- Variations 1 : evolution of the X inactivation center
- Variations 2 : stability of the inactive X
- Variations 3 : choice of active X
- The single active X
- Mosaicism
- Epimutations, chromatin disorders and sex differences in phenotype
- Determinants of female phenotypes.