Contact
Email: victor.sanchez(at)gmi.oeaw.ac.at
Telephone: +43 1 79044/9838
https://orcid.org/0000-0001-5320-6633
FORMER AND CURRENT POSITIONS
since 2019 - PhD candidate in the Dagdas Group
2019 - MSc in Molecular Genetics and Biotechnology at the University of Sevilla, Spain
2018 - BSc in Biochemistry at the University of Sevilla, Spain
Research Projects
Evolution of Selective Autophagy Receptors in Plants
Together with the PhD student Marintia Nava and the Postdoc Marion Clavel, we are working on the discovery and mechanistic characterization of selective autophagy players.
C53 and Ufmylation Regulation in Endoplasmic Reticulum Autophagy (ER-phagy)
Led by PhD Student Lorenzo Picchianti and Postdoc Ni Zhan, we want to understand the molecular basis of selective cargo recruitment of C53-mediated autophagy and its regulation by UFMylation.
Research interests
I find it fascinating that autophagy, a major cellular quality control pathway, can selectively target a specific substrate for its degradation. I am interested in the mechanistic characterization of selective autophagy players that fulfill this role.
Publications
Journal Publication (4)
Clavel, M; Bianchi, A; Kobylinska, R; Groh, R; Ma, J et al. [..] (2024) PREPRINT: Metabolic enzymes moonlight as selective autophagy receptors to protect plants against viral-induced cellular damage. biorXiv.
Otegui, Marisa; Steelheart, Charlotte; Ma, Wenlong; Ma, Juncai; Kang, Byung-Ho et al. [..] (2024) Vacuolar Degradation of Plant Organelles. Plant Cell.
De la Concepcion, JC; Fujisaki, K; Bentham, AR; Cruz Mireles, N; Sanchez de Medina Hernandez, V et al. [..] (2022) PREPRINT: Binding of a blast fungus Zinc-finger fold effector to a hydrophobic pocket in the host exocyst subunit Exo70 modulates immune recognition in rice. biorXiv.
Picchianti, L; Sanchez de Medina Hernandez, V; Zhan, N; Irwin, NAT; Stephani, M et al. [..] (2022) PREPRINT: Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and C53-mediated autophagy. biorXiv.
More Publications
- Serrano-Bueno, G., de los Reyes, P., Chini, A., Ferreras-Garrucho, G., Sánchez de Medina Hernández, V., … & Valverde, F. (2022). Regulation of floral senescence in Arabidopsis by coordinated action of CONSTANS and jasmonate signaling. Mol. Plant15 (11), 1710-1724, doi: doi.org/10.1016/j.molp.2022.09.017
- Aniento, F., Sánchez de Medina Hernández, V., Dagdas, Y., Rojas-Pierce, M., & Russinova, E. (2022). Molecular mechanisms of endomembrane trafficking in plants. The Plant Cell, 34(1), 146-173.
- Serrano-Bueno, G., Sánchez de Medina Hernández, V., & Valverde, F. (2021). Photoperiodic Signaling and Senescence, an Ancient Solution to a Modern Problem?. Frontiers in Plant Science, 12, 342
- Stephani, M., Picchianti, L., Gajic, A., Beveridge, R., Skarwan, E., de Medina Hernandez, V. S., ... & Dagdas, Y. (2020). A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress. Elife, 9, e58396.
