Jürgen Knoblich
Full Member of the Division of Mathematics and Natural Sciences since 2013
- IMBA – Institute of Molecular Biotechnology of the OAW , stellvertretender Direktor
- Institute of Artificial Intelligence, Center for Medical Data Science, Medical University of Vienna
Contact:
juergen.knoblich(at)imba.oeaw.ac.at
Research Areas:
- Biology
- Developmental biology
- Genetics
- Molecular biology
- Stem cell research
- Cell biology
Profile:
Publications:
Selected Memberships:
- Päpstliche Akademie der Wissenschaften
- International Society for Stem Cell Research ISSCR, board of directors
- Academia Europaea
- European Molecular Biology Organization EMBO
- American Society for Cell Biology ASCB
Selected Prizes:
- Preis der Stadt Wien für herausragende Leistungen im Bereich Mathematik, Informatik, Naturwissenschaft, Technik
- Wittgenstein-Preis des Wissenschaftsfonds FWF
- 2 ERC Advanced Grants
- Erwin Schrödinger-Preis der ÖAW
- 2023 Alfred Hauptmann Preis (Kategorie Grundlagenforschung) der Deutschen und Österreichischen Gesellschaften für Epileptologie (DGfE & ÖGfE) und der Schweizerischen Epilepsie-Liga
Selected Publications:
- Eichmüller, Oliver; Corsini, Nina; Vértesy, Ábel; Morassut, Ilaria; Scholl, Theresa et al. [..] (2022) Amplification of human interneuron progenitors promotes brain tumors and neurological defects. Science, Bd. 375 (6579), S. eabf5546.
- Esk C., Lindenhofer D., Haendeler S., Wester R.A., Pflug F., Schroeder B., Bagley J.A., Elling U., Zuber J., von Haeseler A., Knoblich J.A. (2020) A human tissue screen identifies a regulator of ER secretion as a brain-size determinant. Science 370(6519), 935-941.
- Bonnay F., Veloso A., Steinmann V., Köcher T., Abdusselamoglu M.D., Bajaj S., Rivelles E., Landskron L., Esterbauer H., Zinzen R.P. and Knoblich J.A. (2020). Oxidative metabolism drives immortalization of neural stem cells during tumorigenesis. Cell 182(6), 1490-1507.
- Eroglu, E., Burkard, T. R., Jiang, Y., Saini, N., Homem, C. C., Reichert, H., and Knoblich, J. A. (2014). SWI/SNF Complex Prevents Lineage Reversion and Induces Temporal Patterning in Neural Stem Cells. Cell 156, 1259-1273.
- Lancaster, M. A., Renner, M., Martin, C. A., Wenzel, D., Bicknell, L. S., Hurles, M. E., Homfray, T., Penninger, J. M., Jackson, A. P., and Knoblich, J. A. (2013). Cerebral organoids model human brain development and microcephaly. Nature 501, 373-379.