Jukka Jernvall
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Jernvall received his Ph.D. in evolutionary biology in 1995. His thesis investigating the evolution and development of mammalian molar cusp patterns was supervised by Irma Thesleff and Mikael Fortelius. This led to the description of enamel knot as molecular signaling centers in teeth. He also discovered and coined the term ‘secondary enamel knot’, previously overlooked signaling centers regulating tooth cusp development. This discovery helped to mechanistically link molecular regulation of growth and differentiation to shape. Later, Jernvall has focused on the modelling of three-dimensional dentition phenotypes. He has studied why certain dentition patterns arise several times during the course of evolution, while other patterns occur only rarely. Jernvall's team has developed several methods from computer modeling of organ development to three-dimensional analysis of biological shape development and function. Current research ranges from mutant mice in the laboratory to evolutionary diversity in the fossil record and to seal genomics. Provided by Wikipedia
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Published: 1995
Superior document: Acta zoologica Fennica 198
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Published: [2006]
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